2A07

Crystal Structure of Foxp2 bound Specifically to DNA.

Functional Information from GO Data

Chain	GOid	namespace	contents
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription
F	0043565	molecular_function	sequence-specific DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006355	biological_process	regulation of DNA-templated transcription
G	0043565	molecular_function	sequence-specific DNA binding
H	0003700	molecular_function	DNA-binding transcription factor activity
H	0006355	biological_process	regulation of DNA-templated transcription
H	0043565	molecular_function	sequence-specific DNA binding
I	0003700	molecular_function	DNA-binding transcription factor activity
I	0006355	biological_process	regulation of DNA-templated transcription
I	0043565	molecular_function	sequence-specific DNA binding
J	0003700	molecular_function	DNA-binding transcription factor activity
J	0006355	biological_process	regulation of DNA-templated transcription
J	0043565	molecular_function	sequence-specific DNA binding
K	0003700	molecular_function	DNA-binding transcription factor activity
K	0006355	biological_process	regulation of DNA-templated transcription
K	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 601

Chain	Residue
F	SER557
F	LEU558
F	HIS559
F	HOH613

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG H 602

Chain	Residue
H	HOH397
H	LEU556
H	HIS559
H	PHE562

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG I 603

Chain	Residue
I	LEU558
I	HIS559
I	SER557

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG G 604

Chain	Residue
G	LEU556
G	HIS559
G	PHE562

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG J 605

Chain	Residue
J	LEU556
J	SER557
J	HIS559
J	PHE562
J	HOH673

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG K 606

Chain	Residue
D	HOH24
K	LEU556
K	SER557
K	HIS559
K	PHE562
K	HOH645

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Functional Information from PROSITE/UniProt

site_id	PS00658
Number of Residues	7
Details	FORK_HEAD_2 Fork head domain signature 2. WKNAVRH

Chain	Residue	Details
F	TRP548-HIS554

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