2A07
Crystal Structure of Foxp2 bound Specifically to DNA.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0043565 | molecular_function | sequence-specific DNA binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0043565 | molecular_function | sequence-specific DNA binding |
| H | 0003700 | molecular_function | DNA-binding transcription factor activity |
| H | 0006355 | biological_process | regulation of DNA-templated transcription |
| H | 0043565 | molecular_function | sequence-specific DNA binding |
| I | 0003700 | molecular_function | DNA-binding transcription factor activity |
| I | 0006355 | biological_process | regulation of DNA-templated transcription |
| I | 0043565 | molecular_function | sequence-specific DNA binding |
| J | 0003700 | molecular_function | DNA-binding transcription factor activity |
| J | 0006355 | biological_process | regulation of DNA-templated transcription |
| J | 0043565 | molecular_function | sequence-specific DNA binding |
| K | 0003700 | molecular_function | DNA-binding transcription factor activity |
| K | 0006355 | biological_process | regulation of DNA-templated transcription |
| K | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG F 601 |
| Chain | Residue |
| F | SER557 |
| F | LEU558 |
| F | HIS559 |
| F | HOH613 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG H 602 |
| Chain | Residue |
| H | HOH397 |
| H | LEU556 |
| H | HIS559 |
| H | PHE562 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG I 603 |
| Chain | Residue |
| I | LEU558 |
| I | HIS559 |
| I | SER557 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG G 604 |
| Chain | Residue |
| G | LEU556 |
| G | HIS559 |
| G | PHE562 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG J 605 |
| Chain | Residue |
| J | LEU556 |
| J | SER557 |
| J | HIS559 |
| J | PHE562 |
| J | HOH673 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG K 606 |
| Chain | Residue |
| D | HOH24 |
| K | LEU556 |
| K | SER557 |
| K | HIS559 |
| K | PHE562 |
| K | HOH645 |
Functional Information from PROSITE/UniProt
| site_id | PS00658 |
| Number of Residues | 7 |
| Details | FORK_HEAD_2 Fork head domain signature 2. WKNAVRH |
| Chain | Residue | Details |
| F | TRP548-HIS554 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 540 |
| Details | DNA_BIND: Fork-head => ECO:0000255|PROSITE-ProRule:PRU00089 |
| Chain | Residue | Details |
| F | ARG504-LEU594 | |
| G | ARG504-LEU594 | |
| H | ARG504-LEU594 | |
| I | ARG504-LEU594 | |
| J | ARG504-LEU594 | |
| K | ARG504-LEU594 |
