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5C3E
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CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Barnes, C.O., Calero, M., Malik, I., Spahr, H., Zhang, Q., Pullara, F., Kaplan, C.D., Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C44
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CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Barnes, C.O., Calero, M., Malik, I., Spahr, H., Zhang, Q., Pullara, F., Kaplan, C.D., Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4A
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CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Barnes, C.O., Calero, M., Malik, I., Saphr, H., Zhang, Q., Pullara, F., Kaplan, C.D., Calero, G.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4J
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CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Barnes, C.O., Calero, M., Malik, I., Spahr, H., Zhang, Q., Pullara, F., Kaplan, C.D., Calero, G.
Deposit date:2015-06-18
Release date:2015-08-26
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
5C4X
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CRYSTAL STRUCTURE OF A TRANSCRIBING RNA POLYMERASE II COMPLEX REVEALS A COMPLETE TRANSCRIPTION BUBBLE
Descriptor:DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Barnes, C.O., Calero, M., Malik, I., Spahr, H., Zhang, Q., Pullara, F., Kaplan, C.D., Calero, G.
Deposit date:2015-06-18
Release date:2015-08-26
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
Mol.Cell, 59, 2015
6CH7
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XFEL CRYSTAL STRUCTURE OF A NATIVELY-GLYCOSYLATED BG505 SOSIP.664 HIV-1 ENVELOPE TRIMER IN COMPLEX WITH THE BROADLY-NEUTRALIZING ANTIBODIES BG18 AND 35O22
Descriptor:Envelope glycoprotein gp41, 35O22 Heavy Chain, 35O22 Light Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH8
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CRYSTAL STRUCTURE OF A NATIVELY-GLYCOSYLATED BG505 SOSIP.664 HIV-1 ENVELOPE TRIMER IN COMPLEX WITH THE BROADLY-NEUTRALIZING ANTIBODIES BG18 AND 35O22
Descriptor:Envelope glycoprotein gp41, 35O22 Heavy Chain, 35O22 Light Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CH9
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CRYSTAL STRUCTURE OF A NATIVELY-GLYCOSYLATED B41 SOSIP.664 HIV-1 ENVELOPE TRIMER IN COMPLEX WITH THE BROADLY-NEUTRALIZING ANTIBODIES BG18 AND 35O22
Descriptor:Envelope glycoprotein gp41, 35O22 Heavy Chain, 35O22 Light Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (4.85 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6CHB
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CRYSTAL STRUCTURE OF A NATIVELY-GLYCOSYLATED BG505 SOSIP.664 HIV-1 ENVELOPE TRIMER IN COMPLEX WITH THE BROADLY-NEUTRALIZING ANTIBODIES BG18 AND IOMA
Descriptor:Envelope glycoprotein gp41, Envelope glycoprotein gp120, BG18 Heavy Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2018-02-22
Release date:2018-05-02
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (6.801 Å)
Cite:Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope.
Nat Commun, 9, 2018
6OIV
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XFEL STRUCTURE OF ESCHERICHIA COLI DGTPASE
Descriptor:Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION, SULFATE ION
Authors:Barnes, C.O., Wu, Y., Calero, G.
Deposit date:2019-04-09
Release date:2019-06-05
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIW
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STRUCTURE OF ESCHERICHIA COLI DGTPASE BOUND TO DGTP-1-THIOL
Descriptor:Deoxyguanosinetriphosphate triphosphohydrolase, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Barnes, C.O., Wu, Y., Calero, G.
Deposit date:2019-04-09
Release date:2019-05-15
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIX
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STRUCTURE OF ESCHERICHIA COLI DGTPASE BOUND TO GTP
Descriptor:Deoxyguanosinetriphosphate triphosphohydrolase, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
Authors:Barnes, C.O., Wu, Y., Calero, G.
Deposit date:2019-04-09
Release date:2019-05-08
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OIY
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STRUCTURE OF ESCHERICHIA COLI BOUND TO DGTP
Descriptor:Deoxyguanosinetriphosphate triphosphohydrolase, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
Authors:Barnes, C.O., Wu, Y., Calero, G.
Deposit date:2019-04-09
Release date:2019-05-15
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6XCM
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STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE C105 NEUTRALIZING ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, C105 Fab Heavy Chain, C105 Fab Light Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
Cell(Cambridge,Mass.), 2020
6XCN
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STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE C105 NEUTRALIZING ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, C105 Fab Heavy Chain, C105 Fab Light Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
Cell(Cambridge,Mass.), 2020
6EDU
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B41 SOSIP.664 IN COMPLEX WITH SOLUBLE CD4 (D1-D2), THE CO-RECEPTOR MIMICKING ANTIBODY 21C AND THE BROADLY NEUTRALIZING ANTIBODY 8ANC195
Descriptor:Envelope glycoprotein gp160, T-cell surface glycoprotein CD4, 21c Fab VH domain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2018-08-11
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion.
Cell Host Microbe, 24, 2018
6OI7
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SE-MET STRUCTURE OF APO- ESCHERICHIA COLI DGTPASE
Descriptor:Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION, SULFATE ION
Authors:Calero, G., Barnes, C.O., Wu, Y.
Deposit date:2019-04-08
Release date:2019-05-29
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OKP
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B41 SOSIP.664 IN COMPLEX WITH THE SILENT-FACE ANTIBODY SF12 AND V3-TARGETING ANTIBODY 10-1074
Descriptor:Envelope glycoprotein gp41, Envelope glycoprotein gp120, 10-1074 Heavy Chain,10-1074 Heavy Chain, ...
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6OKQ
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CRYSTAL STRUCTURE OF THE SF12 FAB
Descriptor:SF12 Fab Heavy Chain,SF12 Fab Heavy Chain, SF12 Fab Light Chain,SF12 Fab Light Chain
Authors:Barnes, C.O., Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6XCA
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CRYSTAL STRUCTURE OF AN ANTI-SARS-COV-2 HUMAN NEUTRALIZING ANTIBODY FAB FRAGMENT, C105
Descriptor:C105 Heavy Chain, C105 Light Chain, SULFATE ION
Authors:Sharaf, N.G., Barnes, C.O., Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
Cell(Cambridge,Mass.), 2020
6UDJ
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HIV-1 BNAB 1-18 IN COMPLEX WITH BG505 SOSIP.664 AND 10-1074
Descriptor:10-1074 Fab Heavy Chain, 1-18 Fab Light Chain, 10-1074 Fab Light Chain, ...
Authors:Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J.
Deposit date:2019-09-19
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
6UDK
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HIV-1 BNAB 1-55 IN COMPLEX WITH MODIFIED BG505 SOSIP-BASED IMMUNOGEN RC1 AND 10-1074
Descriptor:RC1 variant of HIV-1 Env glycoprotein gp120, 10-1074 Fab Heavy Chain, 10-1074 Fab Light Chain, ...
Authors:Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J.
Deposit date:2019-09-19
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Cell, 180, 2020
4PNJ
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RECOMBINANT SPERM WHALE P6 MYOGLOBIN SOLVED WITH SINGLE PULSE FREE ELECTRON LASER DATA
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Cohen, A., Gonzalez, A., Lam, W., Lyubimov, A., Sauter, N., Tsai, Y., Uervirojnangkoorn, M., Brunger, A., Soltis, M.
Deposit date:2014-05-23
Release date:2014-11-05
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 111, 2014
5JK7
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THE X-RAY STRUCTURE OF THE DDB1-DCAF1-VPR-UNG2 COMPLEX
Descriptor:DNA damage-binding protein 1, Protein VPRBP, Uracil-DNA glycosylase, ...
Authors:Calero, G., Ahn, J., Wu, Y.
Deposit date:2016-04-26
Release date:2016-10-05
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction.
Nat.Struct.Mol.Biol., 23, 2016
5TX2
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MINIATURE TGF-BETA2 3-MUTANT MONOMER
Descriptor:Transforming growth factor beta-2
Authors:Taylor, A.B., Kim, S.K., Hart, P.J., Hinck, A.P.
Deposit date:2016-11-15
Release date:2017-03-01
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling.
J. Biol. Chem., 292, 2017
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