Author results

3B44
  • Download 3b44
  • View 3b44
Molmil generated image of 3b44
CRYSTAL STRUCTURE OF GLPG W136A MUTANT
分子名称:glpG, B-NONYLGLUCOSIDE
著者Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
登録日2007-10-23
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
3B45
  • Download 3b45
  • View 3b45
Molmil generated image of 3b45
CRYSTAL STRUCTURE OF GLPG AT 1.9A RESOLUTION
分子名称:glpG, B-NONYLGLUCOSIDE
著者Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
登録日2007-10-23
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
6A8U
  • Download 6a8u
  • View 6a8u
Molmil generated image of 6a8u
PHOQ SENSOR DOMAIN (WILD TYPE): ANALYSIS OF INTERNAL CAVITY
分子名称:Sensor protein PhoQ
著者Yoshitani, K., Ishii, E., Taniguchi, K., Sugimoto, H., Shiro, Y., Mori, H., Akiyama, Y., Kato, A., Utsumi, R., Eguchi, Y.
登録日2018-07-10
公開日2019-01-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
Biosci. Biotechnol. Biochem., 83, 2019
6A8V
  • Download 6a8v
  • View 6a8v
Molmil generated image of 6a8v
PHOQ SENSOR DOMAIN (D179R MUTANT): ANALYSIS OF INTERNAL CAVITY
分子名称:Sensor protein PhoQ
著者Yoshitani, K., Ishii, E., Taniguchi, K., Sugimoto, H., Shiro, Y., Mori, H., Akiyama, Y., Kato, A., Utsumi, R., Eguchi, Y.
登録日2018-07-10
公開日2019-01-30
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of an internal cavity in the PhoQ sensor domain for PhoQ activity and SafA-mediated control.
Biosci. Biotechnol. Biochem., 83, 2019
1WLF
  • Download 1wlf
  • View 1wlf
Molmil generated image of 1wlf
STRUCTURE OF THE N-TERMINAL DOMAIN OF PEX1 AAA-ATPASE: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN
分子名称:Peroxisome biogenesis factor 1, SULFATE ION
著者Shiozawa, K., Maita, N., Tomii, K., Seto, A., Goda, N., Tochio, H., Akiyama, Y., Shimizu, T., Shirakawa, M., Hiroaki, H.
登録日2004-06-25
公開日2004-09-07
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the N-terminal Domain of PEX1 AAA-ATPase: CHARACTERIZATION OF A PUTATIVE ADAPTOR-BINDING DOMAIN
J.Biol.Chem., 279, 2004
5B1S
  • Download 5b1s
  • View 5b1s
Molmil generated image of 5b1s
CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH 2-(2-FLUOROPHENYL)ETHANAMINE
分子名称:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
著者Amano, Y., Tateishi, Y.
登録日2015-12-17
公開日2016-12-21
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease
Sci Rep, 7, 2017
5Y4P
  • Download 5y4p
  • View 5y4p
Molmil generated image of 5y4p
CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH 5-METHOXY-2-(5-METHYL-4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOL
分子名称:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
著者Amano, Y., Tateishi, Y.
登録日2017-08-04
公開日2018-08-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
To Be Published
5Y4Q
  • Download 5y4q
  • View 5y4q
Molmil generated image of 5y4q
CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI SPERMIDINE SYNTHASE IN COMPLEX WITH N-(4-METHOXYPHENYL)QUINOLIN-4-AMINE
分子名称:Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, ...
著者Amano, Y., Tateishi, Y.
登録日2017-08-04
公開日2018-08-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
To Be Published
3UBB
  • Download 3ubb
  • View 3ubb
Molmil generated image of 3ubb
THE CRYSTAL STRUCTURE OF GLPG IN COMPLEX WITH A PHOSPHONOFLUORIDATE INHIBITOR
分子名称:Rhomboid protease glpG, propan-2-yl hydrogen (S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl]phosphonate
著者Xue, Y., Ha, Y.
登録日2011-10-24
公開日2012-06-13
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.
Biochemistry, 51, 2012
6AIT
  • Download 6ait
  • View 6ait
Molmil generated image of 6ait
CRYSTAL STRUCTURE OF E. COLI BEPA
分子名称:Beta-barrel assembly-enhancing protease, ZINC ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Umar, M.S.M., Tanaka, Y., Kamikubo, H., Tsukazaki, T.
登録日2018-08-24
公開日2018-12-26
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Structural Basis for the Function of the beta-Barrel Assembly-Enhancing Protease BepA.
J. Mol. Biol., 431, 2019
5XI8
  • Download 5xi8
  • View 5xi8
Molmil generated image of 5xi8
STRUCTURE AND FUNCTION OF THE TPR DOMAIN
分子名称:Beta-barrel assembly-enhancing protease
著者Tanaka, Y., Tsukazaki, T.
登録日2017-04-26
公開日2017-10-18
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The TPR domain of BepA is required for productive interaction with substrate proteins and the beta-barrel assembly machinery complex.
Mol. Microbiol., 106, 2017
3WKL
  • Download 3wkl
  • View 3wkl
Molmil generated image of 3wkl
THE PERIPLASMIC PDZ TANDEM FRAGMENT OF THE RSEP HOMOLOGUE FROM AQUIFEX AEOLICUS
分子名称:Putative Zinc Metalloprotease AQ_1964
著者Nogi, T., Tabata, S., Tamura-kawakami, K., Takagi, J.
登録日2013-10-28
公開日2013-12-18
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A Structure-Based Model of Substrate Discrimination by a Noncanonical PDZ Tandem in the Intramembrane-Cleaving Protease RseP
Structure, 22, 2013
3WKM
  • Download 3wkm
  • View 3wkm
Molmil generated image of 3wkm
THE PERIPLASMIC PDZ TANDEM FRAGMENT OF THE RSEP HOMOLOGUE FROM AQUIFEX AEOLICUS IN COMPLEX WITH THE FAB FRAGMENT
分子名称:Putative zinc metalloprotease aq_1964, MOUSE IGG1-KAPPA FAB (HEAVY CHAIN), MOUSE IGG1-KAPPA FAB (LIGHT CHAIN)
著者Nogi, T., Tabata, S., Tamura-kawakami, K., Takagi, J.
登録日2013-10-28
公開日2013-12-18
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Structure-Based Model of Substrate Discrimination by a Noncanonical PDZ Tandem in the Intramembrane-Cleaving Protease RseP
Structure, 22, 2013
2ZPL
  • Download 2zpl
  • View 2zpl
Molmil generated image of 2zpl
CRYSTAL STRUCTURE ANALYSIS OF PDZ DOMAIN A
分子名称:Regulator of sigma E protease, NICKEL (II) ION, GLYCEROL
著者Inaba, K., Suzuki, M.
登録日2008-07-17
公開日2008-10-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure analysis of PDZ-domain A
To be Published
2ZPM
  • Download 2zpm
  • View 2zpm
Molmil generated image of 2zpm
CRYSTAL STRUCTURE ANALYSIS OF PDZ DOMAIN B
分子名称:Regulator of sigma E protease
著者Inaba, K., Suzuki, M.
登録日2008-07-17
公開日2008-10-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Crystal Structure analysis of PDZ-domain B
To be Published
5AZT
  • Download 5azt
  • View 5azt
Molmil generated image of 5azt
TERNARY COMPLEX OF HPPARALPHA LIGAND BINDING DOMAIN, 17-OXODHA AND A SRC1 PEPTIDE
分子名称:Peroxisome proliferator-activated receptor alpha, 15-meric peptide from Nuclear receptor coactivator 1, (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid
著者Egawa, D., Itoh, T., Yamamoto, K.
登録日2015-10-23
公開日2016-07-06
最終更新日2016-07-13
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016
5AZV
  • Download 5azv
  • View 5azv
Molmil generated image of 5azv
CRYSTAL STRUCTURE OF HPPARGAMMA LIGAND BINDING DOMAIN COMPLEXED WITH 17-OXODHA
分子名称:Peroxisome proliferator-activated receptor gamma, (4~{Z},7~{Z},10~{Z},13~{Z},19~{Z})-17-oxidanylidenedocosa-4,7,10,13,19-pentaenoic acid
著者Egawa, D., Itoh, T., Yamamoto, K.
登録日2015-10-23
公開日2016-07-06
最終更新日2016-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献17-OxoDHA Is a PPAR alpha/gamma Dual Covalent Modifier and Agonist
Acs Chem.Biol., 2016