3UBB

The crystal structure of GlpG in complex with a phosphonofluoridate inhibitor

Summary for 3UBB

• Entry DOI: 10.2210/pdb3ubb/pdb
• Descriptor: Rhomboid protease glpG, propan-2-yl hydrogen (S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}ethyl]phosphonate (3 entities in total)
• Functional Keywords: helix bundle, membrane, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 20829.59

Authors

Xue, Y.,Ha, Y. (deposition date: 2011-10-24, release date: 2012-06-13, Last modification date: 2019-07-17)

• Primary citation: Xue, Y.,Chowdhury, S.,Liu, X.,Akiyama, Y.,Ellman, J.,Ha, Y.; Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S' Subsites.; Biochemistry, 51:3723-3731, 2012; PubMed: 22515733; DOI: 10.1021/bi300368b

Experimental method

X-RAY DIFFRACTION (2.601 Å)