7CQC

The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 181 and 184

Summary for 7CQC

• Entry DOI: 10.2210/pdb7cqc/pdb
• Descriptor: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, Fab of NZ-1, Putative zinc metalloprotease aq_1964,PA14 from Podoplanin,Putative zinc metalloprotease aq_1964, ... (4 entities in total)
• Functional Keywords: soluble domain, fab complex, membrane protein, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 3
• Total formula weight: 67892.78

Authors

Aruga, R.,Tamura-Sakaguchi, R.,Nogi, T. (deposition date: 2020-08-10, release date: 2021-05-19, Last modification date: 2023-11-29)

• Primary citation: Tamura-Sakaguchi, R.,Aruga, R.,Hirose, M.,Ekimoto, T.,Miyake, T.,Hizukuri, Y.,Oi, R.,Kaneko, M.K.,Kato, Y.,Akiyama, Y.,Ikeguchi, M.,Iwasaki, K.,Nogi, T.; Moving toward generalizable NZ-1 labeling for 3D structure determination with optimized epitope-tag insertion.; Acta Crystallogr D Struct Biol, 77:645-662, 2021; PubMed: 33950020; DOI: 10.1107/S2059798321002527

Experimental method

X-RAY DIFFRACTION (2.5 Å)