Author results

2LSP
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SOLUTION STRUCTURES OF BRD4 SECOND BROMODOMAIN WITH NF-KB-K310AC PEPTIDE
分子名称:NF-kB-K310ac peptide, Bromodomain-containing protein 4
著者Zhang, G., Liu, R., Zhong, Y., Plotnikov, A.N., Zhang, W., Rusinova, E., Gerona-Nevarro, G., Moshkina, N., Joshua, J., Chuang, P.Y., Ohlmeyer, M., He, J., Zhou, M.-M.
登録日2012-05-03
公開日2012-07-18
最終更新日2013-08-28
実験手法SOLUTION NMR
主引用文献Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
J.Biol.Chem., 287, 2012
1SWV
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CRYSTAL STRUCTURE OF THE D12A MUTANT OF PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM
分子名称:phosphonoacetaldehyde hydrolase, MAGNESIUM ION
著者Zhang, G., Morais, M.C., Dai, J., Zhang, W., Dunaway-Mariano, D., Allen, K.N.
登録日2004-03-30
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
1SWW
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CRYSTAL STRUCTURE OF THE PHOSPHONOACETALDEHYDE HYDROLASE D12A MUTANT COMPLEXED WITH MAGNESIUM AND SUBSTRATE PHOSPHONOACETALDEHYDE
分子名称:phosphonoacetaldehyde hydrolase, MAGNESIUM ION, PHOSPHONOACETALDEHYDE
著者Zhang, G., Morais, M.C., Dai, J., Zhang, W., Dunaway-Mariano, D., Allen, K.N.
登録日2004-03-30
公開日2004-10-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
1AB8
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RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX
分子名称:ADENYLYL CYCLASE, FORSKOLIN
著者Zhang, G., Hurley, J.H.
登録日1997-02-04
公開日1997-05-15
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the adenylyl cyclase catalytic core.
Nature, 386, 1997
1BDF
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STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE ALPHA SUBUNIT N-TERMINAL DOMAIN
分子名称:RNA POLYMERASE ALPHA SUBUNIT
著者Zhang, G., Darst, S.A.
登録日1998-05-08
公開日1999-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Escherichia coli RNA polymerase alpha subunit amino-terminal domain.
Science, 281, 1998
1PTQ
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PROTEIN KINASE C DELTA CYS2 DOMAIN
分子名称:PROTEIN KINASE C DELTA TYPE, ZINC ION
著者Zhang, G., Hurley, J.H.
登録日1995-05-11
公開日1995-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
Cell(Cambridge,Mass.), 81, 1995
1PTR
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PROTEIN KINASE C DELTA CYS2 DOMAIN COMPLEXED WITH PHORBOL-13-ACETATE
分子名称:PROTEIN KINASE C DELTA TYPE, ZINC ION, 13-ACETYLPHORBOL
著者Zhang, G., Hurley, J.H.
登録日1995-05-11
公開日1995-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
Cell(Cambridge,Mass.), 81, 1995
1ZOL
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NATIVE BETA-PGM
分子名称:beta-phosphoglucomutase, MAGNESIUM ION
著者Zhang, G., Tremblay, L.W., Dai, J., Wang, L., Dunaway-Mariano, D., Allen, K.N.
登録日2005-05-13
公開日2005-08-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis
Biochemistry, 44, 2005
1OQD
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CRYSTAL STRUCTURE OF STALL-1 AND BCMA
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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CRYSTAL STRUCTURE OF STALL-1 WITH BAFF-R
分子名称:Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1HSJ
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SARR MBP FUSION STRUCTURE
分子名称:FUSION PROTEIN CONSISTING OF STAPHYLOCOCCUS ACCESSORY REGULATOR PROTEIN R AND MALTOSE BINDING PROTEIN, ALPHA-D-GLUCOSE
著者Zhang, G.
登録日2000-12-26
公開日2001-06-06
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the SarR protein from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 98, 2001
2P5B
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THE COMPLEX STRUCTURE OF JMJD2A AND TRIMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ...
著者Zhang, G., Chen, Z., Zang, J., Hong, X., Shi, Y.
登録日2007-03-14
公開日2007-06-12
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
1FEZ
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THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG
分子名称:PHOSPHONOACETALDEHYDE HYDROLASE, MAGNESIUM ION, TUNGSTATE(VI)ION
著者Morais, M.C., Zhang, W., Baker, A.S., Zhang, G., Dunaway-Mariano, D., Allen, K.N.
登録日2000-07-24
公開日2000-10-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily.
Biochemistry, 39, 2000
1RQL
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CRYSTAL STRUCTURE OF PHOSPONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM AND THE INHIBITOR VINYL SULFONATE
分子名称:Phosphonoacetaldehyde Hydrolase, MAGNESIUM ION, VINYLSULPHONIC ACID
著者Morais, M.C., Zhang, G., Zhang, W., Olsen, D.B., Dunaway-Mariano, D., Allen, K.N.
登録日2003-12-05
公開日2004-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis
J.Biol.Chem., 279, 2004
1RQN
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PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH MAGNESIUM
分子名称:Phosphonoacetaldehyde Hydrolase, MAGNESIUM ION
著者Morais, M.C., Zhang, G., Zhang, W., Olsen, D.B., Dunaway-Mariano, D., Allen, K.N.
登録日2003-12-05
公開日2004-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis
J.Biol.Chem., 279, 2004
1LVH
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THE STRUCTURE OF PHOSPHORYLATED BETA-PHOSPHOGLUCOMUTASE FROM LACTOCCOCUS LACTIS TO 2.3 ANGSTROM RESOLUTION
分子名称:beta-phosphoglucomutase, MAGNESIUM ION
著者Lahiri, S.D., Zhang, G., Dunaway-Mariano, D., Allen, K.N.
登録日2002-05-28
公開日2002-08-14
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis.
Biochemistry, 41, 2002
2HFR
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SOLUTION STRUCTURE OF ANTIMICROBIAL PEPTIDE FOWLICIDIN 3
分子名称:Fowlicidin-3
著者Bommineni, Y.R., Dai, H., Gong, Y., Prakash, O., Zhang, G.
登録日2006-06-26
公開日2007-04-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities.
Febs J., 274, 2007
2LQV
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YEBF
分子名称:Protein yebF
著者Prehna, G., Zhang, G., Gong, X., Duszyk, M., Okon, M., Mcintosh, L.P., Weiner, J.H., Strynadka, N.C.J.
登録日2012-03-16
公開日2012-06-13
最終更新日2012-07-25
実験手法SOLUTION NMR
主引用文献A Protein Export Pathway Involving Escherichia coli Porins.
Structure, 20, 2012
6AVS
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC MONOMETHYL-ARGININE (MMA)
分子名称:Lysine-specific demethylase 8, ZINC ION, (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid
著者Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
登録日2017-09-04
公開日2018-02-28
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6AX3
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COMPLEX STRUCTURE OF JMJD5 AND SYMMETRIC DIMETHYL-ARGININE (SDMA)
分子名称:Lysine-specific demethylase 8, N3, N4-DIMETHYLARGININE, ...
著者Lee, S., Liu, H., Wang, Y., Dai, S., Zhang, G.
登録日2017-09-06
公開日2018-02-28
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7.
Sci Rep, 8, 2018
6MEV
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STRUCTURE OF JMJD6 BOUND TO MONO-METHYL ARGININE.
分子名称:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, 2-OXOGLUTARIC ACID, FE (III) ION, ...
著者Lee, S., Zhang, G.
登録日2018-09-07
公開日2019-09-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献JMJD6 bridges BRD4, CDK9, and RNA Polymerase II
To Be Published
6R8I
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PP4R3A EVH1 DOMAIN BOUND TO FXXP MOTIF
分子名称:Serine/threonine-protein phosphatase 4 regulatory subunit 3A, SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER
著者Ueki, Y., Kruse, T., Weisser, M.B., Sundell, G.N., Yoo Larsen, M.S., Lopez Mendez, B., Jenkins, N.P., Garvanska, D.H., Cressey, L., Zhang, G., Davey, N., Montoya, G., Ivarsson, Y., Kettenbach, A., Nilsson, J.
登録日2019-04-02
公開日2019-10-16
実験手法X-RAY DIFFRACTION (1.517 Å)
主引用文献A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 2019
2W7X
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CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019
分子名称:SERINE/THREONINE-PROTEIN KINASE CHK2, N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide, MAGNESIUM ION, ...
著者Jobson, A.G., Lountos, G.T., Lorenzi, P.L., Llamas, J., Connelly, J., Tropea, J.E., Onda, A., Kondapaka, S., Zhang, G., Caplen, N.J., Caredellina, J.H., Monks, A., Self, C., Waugh, D.S., Shoemaker, R.H., Pommier, Y.
登録日2009-01-06
公開日2009-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Cellular Inhibition of Chk2 Kinase and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor Pv1019.
J.Pharmacol.Exp.Ther., 331, 2009
2YIQ
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STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322
分子名称:SERINE/THREONINE-PROTEIN KINASE CHK2, (E)-5-(1-(2-CARBAMIMIDOYLHYDRAZONO)ETHYL)-N-(1H-INDOL-6-YL)-1H-INDOLE-2-CARBOXAMIDE, NITRATE ION
著者Lountos, G.T., Jobson, A.G., Tropea, J.E., Self, C., Zhang, G., Pommier, Y., Shoemaker, R.H., Waugh, D.S.
登録日2011-05-16
公開日2011-09-07
最終更新日2011-10-26
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献X-Ray Structures of Checkpoint Kinase 2 in Complex with Inhibitors that Target its Gatekeeper-Dependent Hydrophobic Pocket.
FEBS Lett., 585, 2011
2YIR
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STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1352
分子名称:SERINE/THREONINE-PROTEIN KINASE CHK2, (E)-N-(5-(2-CARBAMIMIDOYLHYDRAZONO)-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-7-NITRO-1H-INDOLE-2-CARBOXAMIDE, NITRATE ION
著者Lountos, G.T., Jobson, A.G., Tropea, J.E., Self, C., Zhang, G., Pommier, Y., Shoemaker, R.H., Waugh, D.S.
登録日2011-05-16
公開日2011-09-07
最終更新日2011-10-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-Ray Structures of Checkpoint Kinase 2 in Complex with Inhibitors that Target its Gatekeeper-Dependent Hydrophobic Pocket.
FEBS Lett., 585, 2011