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5HKV
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH LINCOMYCIN
Descriptor:23s ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2016-01-14
Release date:2017-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5NRG
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH RB02
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A., Matzov, D., Eyal, Z., Ben Hamou, R., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M.
Deposit date:2017-04-23
Release date:2017-08-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.442 Å)
Cite:Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
5JVH
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THE CRYSTAL STRUCTURE LARGE RIBOSOMAL SUBUNIT (50S) OF DEINOCOCCUS RADIODURANS IN COMPLEX WITH EVERNIMICIN
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Yonath, A.
Deposit date:2016-05-11
Release date:2016-11-09
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
1I94
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CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1I95
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH EDEINE
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1I96
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE TRANSLATION INITIATION FACTOR IF3 (C-TERMINAL DOMAIN)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1I97
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TETRACYCLINE
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Pioletti, M., Schluenzen, F., Harms, J., Zarivach, R., Gluehmann, M., Avila, H., Bartels, H., Jacobi, C., Hartsch, T., Yonath, A., Franceschi, F.
Deposit date:2001-03-18
Release date:2001-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
1NKW
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CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Schluenzen, F., Zarivach, R., Bashan, A., Gat, S., Agmon, I., Bartels, H., Franceschi, F., Yonath, A.
Deposit date:2003-01-05
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:High resolution structure of the large ribosomal subunit from a mesophilic eubacterium
Cell(Cambridge,Mass.), 107, 2001
1OND
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TROLEANDOMYCIN MACROLIDE ANTIBIOTIC
Descriptor:23S RIBOSOMAL RNA, 50S ribosomal protein L22, 50S ribosomal protein L32, ...
Authors:Berisio, R., Schluenzen, F., Harms, J., Bashan, A., Auerbach, T., Baram, D., Yonath, A.
Deposit date:2003-02-27
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into the role of the ribosomal tunnel in cellular regulation
Nat.Struct.Biol., 10, 2003
1P9X
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC
Descriptor:23S RIBOSOMAL RNA, TELITHROMYCIN
Authors:Berisio, R., Harms, J., Schluenzen, F., Zarivach, R., Hansen, H.A., Fucini, P., Yonath, A.
Deposit date:2003-05-13
Release date:2003-08-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insight into the antibiotic action of telithromycin against resistant mutants
J.Bacteriol., 185, 2003
1FKA
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STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Schluenzen, F., Tocilj, A., Zarivach, R., Harms, J., Gluehmann, M., Janell, D., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., Yonath, A.
Deposit date:2000-08-09
Release date:2000-09-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Cell(Cambridge,Mass.), 102, 2000
1DV4
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PARTIAL STRUCTURE OF 16S RNA OF THE SMALL RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS
Descriptor:16S RIBOSOMAL RNA, RIBOSOMAL PROTEIN S5, RIBOSOMAL PROTEIN S7, ...
Authors:Tocilj, A., Schlunzen, F., Janell, D., Gluhmann, M., Hansen, H., Harms, J., Bashan, A., Bartels, H., Agmon, I., Franceschi, F., Yonath, A.
Deposit date:2000-01-19
Release date:2000-02-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The small ribosomal subunit from Thermus thermophilus at 4.5 A resolution: pattern fittings and the identification of a functional site.
Proc.Natl.Acad.Sci.USA, 96, 1999
1J5A
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STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Descriptor:23S RRNA, RIBOSOMAL PROTEIN L4, RIBOSOMAL PROTEIN L22, ...
Authors:Schluenzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., Franceschi, F.
Deposit date:2002-03-06
Release date:2002-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1JZX
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STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Descriptor:23S rRNA, Ribosomal Protein L4, Ribosomal Protein L22, ...
Authors:Schluenzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., Franceschi, F.
Deposit date:2001-09-17
Release date:2001-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1JZY
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STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Descriptor:23S rRNA, Ribosomal Protein L4, Ribosomal Protein L22, ...
Authors:Schluenzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., Franceschi, F.
Deposit date:2001-09-17
Release date:2001-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1JZZ
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STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Descriptor:23S rRNA, Ribosomal Protein L4, Ribosomal Protein L22, ...
Authors:Schluenzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., Franceschi, F.
Deposit date:2001-09-17
Release date:2001-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1K01
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STRUCTURAL BASIS FOR THE INTERACTION OF ANTIBIOTICS WITH THE PEPTIDYL TRANSFERASE CENTER IN EUBACTERIA
Descriptor:23S rRNA, Ribosomal Protein L4, Ribosomal Protein L22, ...
Authors:Schluenzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., Franceschi, F.
Deposit date:2001-09-17
Release date:2001-10-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria.
Nature, 413, 2001
1NJM
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A TRNA ACCEPTOR STEM MIMIC (ASM) AND THE ANTIBIOTIC SPARSOMYCIN
Descriptor:23S ribosomal RNA, tRNA acceptor stem mimic, 50S ribosomal protein L16, ...
Authors:Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
1NJN
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE ANTIBIOTIC SPARSOMYCIN
Descriptor:23S ribosomal RNA, SPARSOMYCIN
Authors:Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
1NJO
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A SHORT SUBSTRATE ANALOG ACCPUROMYCIN (ACCP)
Descriptor:23S ribosomal RNA, RNA ACC(Puromycin)
Authors:Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
1NJP
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THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH A TRNA ACCEPTOR STEM MIMIC (ASM)
Descriptor:23S ribosomal RNA, tRNA acceptor stem mimic, 50S ribosomal protein L16, ...
Authors:Bashan, A., Agmon, I., Zarivatch, R., Schluenzen, F., Harms, J.M., Berisio, R., Bartels, H., Hansen, H.A., Yonath, A.
Deposit date:2003-01-02
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of the ribosomal machinery for Peptide bond formation, translocation, and nascent chain progression
Mol.Cell, 11, 2003
1Z58
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CRYSTAL STRUCTURE OF A COMPLEX OF THE RIBOSOME LARGE SUBUNIT WITH RAPAMYCIN
Descriptor:23S RIBOSOMAL RNA, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Amit, M., Berisio, R., Baram, D., Harms, J., Bashan, A., Yonath, A.
Deposit date:2005-03-17
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A crevice adjoining the ribosome tunnel: Hints for cotranslational folding.
Febs Lett., 579, 2005
2AAR
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STRUCTURE OF TRIGGER FACTOR BINDING DOMAIN IN BIOLOGICALLY HOMOLOGOUS COMPLEX WITH EUBACTERIAL RIBOSOME.
Descriptor:23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L29, ...
Authors:Baram, D., Pyetan, E., Sittner, A., Auerbach-Nevo, T., Bashan, A., Yonath, A.
Deposit date:2005-07-14
Release date:2005-08-23
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of trigger factor binding domain in biologically homologous complex with eubacterial ribosome reveals its chaperone action
Proc.Natl.Acad.Sci.Usa, 102, 2005
2OGM
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE PLEUROMUTILIN DERIVATIVE SB-571519
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE
Authors:Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGN
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THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH THE PLEUROMUTILIN DERIVATIVE SB-280080
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL (PIPERIDIN-4-YLTHIO)ACETATE
Authors:Davidovich, C., Bashan, A., Auerbach-Nevo, T., Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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