5JVH

The crystal structure large ribosomal subunit (50S) of Deinococcus radiodurans in complex with evernimicin

Summary for 5JVH

Entry DOI	10.2210/pdb5jvh/pdb
Descriptor	23S ribosomal RNA, 50S ribosomal protein L15, 50S ribosomal protein L16, ... (30 entities in total)
Functional Keywords	ribosome, antibiotics
Biological source	Deinococcus radiodurans R1 More
Total number of polymer chains	28
Total formula weight	1349716.82
Authors	Yonath, A. (deposition date: 2016-05-11, release date: 2016-11-09, Last modification date: 2024-01-10)
Primary citation	Krupkin, M.,Wekselman, I.,Matzov, D.,Eyal, Z.,Diskin Posner, Y.,Rozenberg, H.,Zimmerman, E.,Bashan, A.,Yonath, A. Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding. Proc.Natl.Acad.Sci.USA, 113:E6796-E6805, 2016 Cited by PubMed: 27791159 DOI: 10.1073/pnas.1614297113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.58 Å)

Structure validation