1H6M | | COVALENT GLYCOSYL-ENZYME INTERMEDIATE OF HEN EGG WHITE LYSOZYME | | Descriptor: | LYSOZYME C, SODIUM ION, 2-deoxy-2-fluoro-alpha-D-glucopyranose, ... | | Authors: | Vocadlo, D.J., Davies, G.J., Laine, R., Withers, S.G. | | Deposit date: | 2001-06-19 | | Release date: | 2001-08-30 | | Last modified: | 2019-03-13 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate
Nature, 412, 2001
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1JAK | | STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE IN COMPLEX WITH (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINIUM CHLORIDE (IFG) | | Descriptor: | Beta-N-acetylhexosaminidase, SULFATE ION, CHLORIDE ION, ... | | Authors: | Mark, B.L., Vocadlo, D.J., Zhao, D., Knapp, S., Withers, S.G., James, M.N. | | Deposit date: | 2001-05-30 | | Release date: | 2001-11-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor.
J.Biol.Chem., 276, 2001
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1M01 | | WILDTYPE STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE IN COMPLEX WITH PRODUCT (GLCNAC) | | Descriptor: | Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ... | | Authors: | J Williams, S., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G. | | Deposit date: | 2002-06-11 | | Release date: | 2003-01-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical
role in substrate-assisted catalysis by orienting the 2-acetamido group
and stabilizing the transition state.
J.Biol.Chem., 277, 2002
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1M03 | | MUTANT STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE (D313A) IN COMPLEX WITH PRODUCT (GLCNAC) | | Descriptor: | Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ... | | Authors: | Williams, S.J., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G. | | Deposit date: | 2002-06-11 | | Release date: | 2002-12-11 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical
role in substrate-assisted catalysis by orienting the 2-acetamido group
and stabilizing the transition state.
J.Biol.Chem., 277, 2002
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1M04 | | MUTANT STREPTOMYCES PLICATUS BETA-HEXOSAMINIDASE (D313N) IN COMPLEX WITH PRODUCT (GLCNAC) | | Descriptor: | Beta-N-acetylhexosaminidase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ... | | Authors: | Williams, S.J., Mark, B.L., Vocadlo, D.J., James, M.N.G., Withers, S.G. | | Deposit date: | 2002-06-11 | | Release date: | 2002-12-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical
role in substrate-assisted catalysis by orienting the 2-acetamido group
and stabilizing the transition state.
J.Biol.Chem., 277, 2002
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1PX8 | | CRYSTAL STRUCTURE OF BETA-D-XYLOSIDASE FROM THERMOANAEROBACTERIUM SACCHAROLYTICUM, A FAMILY 39 GLYCOSIDE HYDROLASE | | Descriptor: | Beta-xylosidase, BETA-D-XYLOPYRANOSE | | Authors: | Yang, J.K., Yoon, H.J., Ahn, H.J., Il Lee, B., Pedelacq, J.D., Liong, E.C., Berendzen, J., Laivenieks, M., Vieille, C., Zeikus, G.J., Vocadlo, D.J., Withers, S.G., Suh, S.W. | | Deposit date: | 2003-07-03 | | Release date: | 2003-12-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase.
J.Mol.Biol., 335, 2004
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1UHV | | CRYSTAL STRUCTURE OF BETA-D-XYLOSIDASE FROM THERMOANAEROBACTERIUM SACCHAROLYTICUM, A FAMILY 39 GLYCOSIDE HYDROLASE | | Descriptor: | Beta-xylosidase, 1,2-DEOXY-2-FLUORO-XYLOPYRANOSE | | Authors: | Yang, J.K., Yoon, H.J., Ahn, H.J., Il Lee, B., Pedelacq, J.D., Liong, E.C., Berendzen, J., Laivenieks, M., Vieille, C., Zeikus, G.J., Vocadlo, D.J., Withers, S.G., Suh, S.W. | | Deposit date: | 2003-07-11 | | Release date: | 2003-12-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of beta-D-xylosidase from Thermoanaerobacterium saccharolyticum, a family 39 glycoside hydrolase.
J.Mol.Biol., 335, 2004
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1ZUN | | CRYSTAL STRUCTURE OF A GTP-REGULATED ATP SULFURYLASE HETERODIMER FROM PSEUDOMONAS SYRINGAE | | Descriptor: | Sulfate adenylyltransferase subunit 2, sulfate adenylate transferase, subunit 1/adenylylsulfate kinase, ... | | Authors: | Mougous, J.D., Lee, D.H., Hubbard, S.C., Schelle, M.W., Vocadlo, D.J., Berger, J.M., Bertozzi, C.R. | | Deposit date: | 2005-05-31 | | Release date: | 2006-01-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis for g protein control of the prokaryotic ATP sulfurylase.
Mol.Cell, 21, 2006
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2CHN | | BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY- NAG-THIAZOLINE COMPLEX | | Descriptor: | GLUCOSAMINIDASE, CALCIUM ION, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ... | | Authors: | Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J. | | Deposit date: | 2006-03-15 | | Release date: | 2006-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
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2CHO | | BACTEROIDES THETAIOTAOMICRON HEXOSAMINIDASE WITH O-GLCNACASE ACTIVITY | | Descriptor: | GLUCOSAMINIDASE, CALCIUM ION, ACETATE ION, ... | | Authors: | Dennis, R.J., Taylor, E.J., Macauley, M.S., Stubbs, K.A., Turkenburg, J.P., Hart, S.J., Black, G.N., Vocadlo, D.J., Davies, G.J. | | Deposit date: | 2006-03-16 | | Release date: | 2006-06-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
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2VC9 | | FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN | | Descriptor: | ALPHA-N-ACETYLGLUCOSAMINIDASE, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, GLYCEROL, ... | | Authors: | Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2VCA | | FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH BETA-N-ACETYL-D-GLUCOSAMINE | | Descriptor: | ALPHA-N-ACETYLGLUCOSAMINIDASE, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ... | | Authors: | Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2VCB | | FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS IN COMPLEX WITH PUGNAC | | Descriptor: | ALPHA-N-ACETYLGLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, CALCIUM ION | | Authors: | Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-18 | | Last modified: | 2011-08-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2VCC | | FAMILY 89 GLYCOSIDE HYDROLASE FROM CLOSTRIDIUM PERFRINGENS | | Descriptor: | ALPHA-N-ACETYLGLUCOSAMINIDASE, GLYCEROL, SULFATE ION, ... | | Authors: | Ficko-Blean, E., Stubbs, K.A., Berg, O., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
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2VVS | | BTGH84 STRUCTURE IN COMPLEX WITH PUGNAC | | Descriptor: | O-GLCNACASE BT_4395, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE | | Authors: | Macauley, M.S., Bubb, A., Martinez-Fleites, C., Davies, G.J., Vocadlo, D.J. | | Deposit date: | 2008-06-11 | | Release date: | 2008-09-30 | | Last modified: | 2011-08-24 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Elevation of Global O-Glcnac Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-Glcnacase Does not Induce Insulin Resistance
J.Biol.Chem., 283, 2008
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2W91 | | STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE FAMILY 85 GLYCOSIDE HYDROLASE, ENDO-D. | | Descriptor: | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D, PENTAETHYLENE GLYCOL | | Authors: | Abbott, D.W., Macauley, M.S., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-01-21 | | Release date: | 2009-01-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Streptococcus Pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight Into Substrate-Assisted Catalysis in Family 85 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2W92 | | STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE FAMILY 85 GLYCOSIDE HYDROLASE, ENDO-D, IN COMPLEX WITH NAG-THIAZOLINE. | | Descriptor: | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D, PENTAETHYLENE GLYCOL, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL | | Authors: | Abbott, D.W., Macauley, M.S., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-01-21 | | Release date: | 2009-01-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Streptococcus Pneumoniae Endohexosaminidase D, Structural and Mechanistic Insight Into Substrate-Assisted Catalysis in Family 85 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WAR | |
2WMF | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 (SP4GH98) IN ITS NATIVE FORM. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WMG | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 (SP4GH98) IN COMPLEX WITH THE LEWISY PENTASACCHARIDE BLOOD GROUP ANTIGEN. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ... | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WMH | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 IN COMPLEX WITH THE H- DISACCHARIDE BLOOD GROUP ANTIGEN. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, BETA-D-GALACTOSE, ALPHA-L-FUCOSE | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WMI | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 IN COMPLEX WITH THE A-TRISACCHARIDE BLOOD GROUP ANTIGEN. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ... | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2012-11-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WMJ | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 (SP3GH98) IN COMPLEX WITH THE B-TRISACCHARIDE BLOOD GROUP ANTIGEN. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, ALPHA D-GALACTOSE, BETA-D-GALACTOSE, ... | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2WMK | | CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLYCOSIDE HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE SP3-BS71 (SP3GH98) IN COMPLEX WITH THE A-LEWISY PENTASACCHARIDE BLOOD GROUP ANTIGEN. | | Descriptor: | FUCOLECTIN-RELATED PROTEIN, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ... | | Authors: | Higgins, M.A., Whitworth, G.E., El Warry, N., Randriantsoa, M., Samain, E., Burke, R.D., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2012-11-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Differential Recognition and Hydrolysis of Host Carbohydrate-Antigens by Streptococcus Pneumoniae Family 98 Glycoside Hydrolases.
J.Biol.Chem., 284, 2009
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2YA0 | | CATALYTIC MODULE OF THE MULTI-MODULAR GLYCOGEN-DEGRADING PNEUMOCOCCAL VIRULENCE FACTOR SPUA | | Descriptor: | PUTATIVE ALKALINE AMYLOPULLULANASE, CALCIUM ION, GLYCEROL, ... | | Authors: | Lammerts van Bueren, A., Ficko-Blean, E., Pluvinage, B., Hehemann, J.H., Higgins, M.A., Deng, L., Ogunniyi, A.D., Stroeher, U.H., Warry, N.E., Burke, R.D., Czjzek, M., Paton, J.C., Vocadlo, D.J., Boraston, A.B. | | Deposit date: | 2011-02-17 | | Release date: | 2011-04-20 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Conformation and Function of a Multimodular Glycogen-Degrading Pneumococcal Virulence Factor.
Structure, 19, 2011
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