2VCB

Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc

Summary for 2VCB

Related2VC9 2VCA 2VCC
DescriptorALPHA-N-ACETYLGLUCOSAMINIDASE, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, CALCIUM ION, ... (4 entities in total)
Functional Keywordsmucopolysaccharidosis, alpha-n-acetylglucosaminidase, family 89 glycoside hydrolase, hydrolase, gh89, naglu, pugnac, sanfilippo disease
Biological sourceCLOSTRIDIUM PERFRINGENS
Total number of polymer chains1
Total molecular weight102666.62
Authors
Ficko-Blean, E.,Stubbs, K.A.,Berg, O.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2007-09-19, release date: 2008-03-18, Last modification date: 2011-08-24)
Primary citation
Ficko-Blean, E.,Stubbs, K.A.,Nemirovsky, O.,Vocadlo, D.J.,Boraston, A.B.
Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105:6560-, 2008
PubMed: 18443291 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.0711491105
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25060.1%5.9%1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vcb
no rotation
Molmil generated image of 2vcb
rotated about x axis by 90°
Molmil generated image of 2vcb
rotated about y axis by 90°