2VCA

Family 89 glycoside hydrolase from Clostridium perfringens in complex with beta-N-acetyl-D-glucosamine

Summary for 2VCA

Related2VC9 2VCB 2VCC
DescriptorALPHA-N-ACETYLGLUCOSAMINIDASE, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ... (6 entities in total)
Functional Keywordsmucopolysaccharidosis, beta-n-acetyl-d-glucosamine, gh89, naglu, sanfilippo disease, hydrolase, alpha-n-acetylglucosaminidase, family 89 glycoside hydrolase
Biological sourceCLOSTRIDIUM PERFRINGENS
Total number of polymer chains1
Total molecular weight102906.85
Authors
Ficko-Blean, E.,Stubbs, K.A.,Berg, O.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2007-09-19, release date: 2008-03-18, Last modification date: 2011-07-13)
Primary citation
Ficko-Blean, E.,Stubbs, K.A.,Nemirovsky, O.,Vocadlo, D.J.,Boraston, A.B.
Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105:6560-, 2008
PubMed: 18443291 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.0711491105
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23050.6%5.1%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vca
no rotation
Molmil generated image of 2vca
rotated about x axis by 90°
Molmil generated image of 2vca
rotated about y axis by 90°