2VC9

Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin

Summary for 2VC9

Related2VCA 2VCB 2VCC
DescriptorALPHA-N-ACETYLGLUCOSAMINIDASE, 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, GLYCEROL, ... (5 entities in total)
Functional Keywordsmucopolysaccharidosis, 2-acetamido-1, 2-dideoxynojirmycin, gh89, naglu, sanfilippo disease, hydrolase, alpha-n-acetylglucosaminidase, family 89 glycoside hydrolase
Biological sourceCLOSTRIDIUM PERFRINGENS
Total number of polymer chains1
Total molecular weight102701.71
Authors
Ficko-Blean, E.,Stubbs, K.A.,Berg, O.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2007-09-19, release date: 2008-03-18, Last modification date: 2011-07-13)
Primary citation
Ficko-Blean, E.,Stubbs, K.A.,Nemirovsky, O.,Vocadlo, D.J.,Boraston, A.B.
Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105:6560-, 2008
PubMed: 18443291 (PDB entries with the same primary citation)
DOI: 10.1073/PNAS.0711491105
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.36 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23870.2%5.3%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vc9
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Molmil generated image of 2vc9
rotated about x axis by 90°
Molmil generated image of 2vc9
rotated about y axis by 90°