Author results

1ZFL
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SOLUTION STRUCTURE OF III-A, THE MAJOR INTERMEDIATE IN THE OXIDATIVE FOLDING OF LEECH CARBOXYPEPTIDASE INHIBITOR
Descriptor:Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L., D'Silva, L., Popowicz, G.M., Aviles, F.X., Holak, T.A., Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
2ABZ
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CRYSTAL STRUCTURE OF C19A/C43A MUTANT OF LEECH CARBOXYPEPTIDASE INHIBITOR IN COMPLEX WITH BOVINE CARBOXYPEPTIDASE A
Descriptor:Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L., Popowicz, G.M., Bronsoms, S., Aviles, F.X., Huber, R., Holak, T.A., Ventura, S.
Deposit date:2005-07-18
Release date:2006-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
2BOA
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HUMAN PROCARBOXYPEPTIDASE A4.
Descriptor:CARBOXYPEPTIDASE A4, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Garcia-Castellanos, R., Bonet-Figueredo, R., Pallares, I., Ventura, S., Aviles, F.X., Vendrell, J., Gomis-Ruth, F.X.
Deposit date:2005-04-08
Release date:2005-12-13
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Detailed Molecular Comparison between the Inhibition Mode of A/B-Type Carboxypeptidases in the Zymogen State and by the Endogenous Inhibitor Latexin.
Cell.Mol.Life Sci., 62, 2005
6FWW
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GFP/KKK. A REDESIGNED GFP WITH IMPROVED SOLUBILITY
Descriptor:Green fluorescent protein
Authors:Varejao, N., Lascorz, J., Gil-Garcia, M., Diaz-Caballero, M., Navarro, S., Ventura, S., Reverter, D.
Deposit date:2018-03-07
Release date:2018-08-01
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.131 Å)
Cite:Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.
Mol. Pharm., 15, 2018
1H20
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SOLUTION STRUCTURE OF THE POTATO CARBOXYPEPTIDASE INHIBITOR
Descriptor:METALLOCARBOXYPEPTIDASE INHIBITOR
Authors:Gonzalez, C., Neira, J.L., Ventura, S., Bronsoms, S., Aviles, F.X., Rico, M.
Deposit date:2002-07-29
Release date:2003-05-09
Last modified:2011-12-28
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Potato Carboxypeptidase Inhibitor by 1H and 15N NMR.
Proteins, 50, 2003
5FO2
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STRUCTURE OF HUMAN TRANSTHYRETIN MUTANT A108I
Descriptor:TRANSTHYRETIN
Authors:Varejao, N., Santanna, R., Saraiva, M.J., Gallego, P., Ventura, S., Reverter, D.
Deposit date:2015-11-17
Release date:2016-11-30
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
5FW6
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STRUCTURE OF HUMAN TRANSTHYRETIN MUTANT A108V
Descriptor:TRANSTHYRETIN
Authors:Gallego, P., Varejao, N., Santanna, R., Saraiva, M.J., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
5FW9
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HUMAN SPECTRIN SH3 DOMAIN D48G, E7Y, K60Y
Descriptor:SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P., Navarro, S., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Human Spectrin SH3 Domain D48G, E7Y, K60Y
To be Published
5FWB
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HUMAN SPECTRIN SH3 DOMAIN D48G, E7F, K60F
Descriptor:SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1
Authors:Gallego, P., Navarro, S., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human Spectrin SH3 Domain D48G, E7F, K60F
To be Published
5FWC
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HUMAN SPECTRIN SH3 DOMAIN D48G, E7A, K60A
Descriptor:SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1, 1,2-ETHANEDIOL, ...
Authors:Gallego, P., Navarro, S., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
6FWD
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN DOUBLE MUTANT R34G/T119M AT PH 5.5
Descriptor:Transthyretin
Authors:Esperante, S., Ventura, S., Reverter, D., Varejao, N.
Deposit date:2018-03-06
Release date:2019-03-20
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Crystal structure of human transthyretin double mutant R34G/T119M at pH 5.5
To Be Published
6FXU
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN MUTANT T119M AT PH 5.5
Descriptor:Transthyretin
Authors:Varejao, N., Esperante, S., Ventura, S., Reverter, D.
Deposit date:2018-03-09
Release date:2019-03-20
Method:X-RAY DIFFRACTION (1.359 Å)
Cite:Crystal structure of human transthyretin mutant T119M at pH 5.5
To Be Published
6FZL
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN DOUBLE MUTANT K35T/T119M
Descriptor:Transthyretin
Authors:Esperante, S., Ventura, S., Reverter, D., Varejao, N.
Deposit date:2018-03-15
Release date:2019-03-27
Method:X-RAY DIFFRACTION (1.446 Å)
Cite:Crystal structure of human transthyretin double mutant K35T/T119M
To Be Published
1ZFI
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SOLUTION STRUCTURE OF THE LEECH CARBOXYPEPTIDASE INHIBITOR
Descriptor:Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L., D'Silva, L., Popowicz, G.M., Aviles, F.X., Holak, T.A., Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
2BO9
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HUMAN CARBOXYPEPTIDASE A4 IN COMPLEX WITH HUMAN LATEXIN.
Descriptor:CARBOXYPEPTIDASE A4, HUMAN LATEXIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Pallares, I., Bonet, R., Garcia-Castellanos, R., Ventura, S., Aviles, F.X., Vendrell, J., Gomis-Rueth, F.X.
Deposit date:2005-04-08
Release date:2005-04-15
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of Human Carboxypeptidase A4 with its Endogenous Protein Inhibitor, Latexin.
Proc.Natl.Acad.Sci.USA, 102, 2005
2V77
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CRYSTAL STRUCTURE OF HUMAN CARBOXYPEPTIDASE A1
Descriptor:CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ZINC ION, ...
Authors:Pallares, I., Fernandez, D., Comellas-Bigler, M., Fernandez-Recio, J., Ventura, S., Aviles, F.X., Vendrell, J.
Deposit date:2007-07-27
Release date:2008-07-01
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Acta Crystallogr. D Biol. Crystallogr., D64, 2008
4D7B
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STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH TOLCAPONE
Descriptor:TRANSTHYRETIN, Tolcapone
Authors:Gallego, P., Sant'anna, R.O., Ventura, S., Reverter, D.
Deposit date:2014-11-21
Release date:2016-01-20
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
5A6I
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V122I TRANSTHYRETIN STRUCTURE IN COMPLEX WITH TOLCALPONE
Descriptor:TRANSTHYRETIN, Tolcapone
Authors:Reverter, D., Gallego, P., Santana, R., Ventura, S.
Deposit date:2015-06-26
Release date:2016-02-24
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Repositioning Tolcapone as a Potent Inhibitor of Transthyretin Amyloidogenesis and its Associated Cellular Toxicity
Nat.Commun., 7, 2016
5AEK
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CRYSTAL STRUCTURE OF THE HUMAN SENP2 C548S IN COMPLEX WITH THE HUMAN SUMO1 K48M F66W
Descriptor:SENTRIN-SPECIFIC PROTEASE 2, SMALL UBIQUITIN-RELATED MODIFIER 1
Authors:Gallego, P., Grana-Montes, R., Espargaro, A., Castillo, V., Torrent, J., Lange, R., Papaleo, E., Lindorff-Larsend, K., Ventura, S., Reverter, D.
Deposit date:2014-12-23
Release date:2016-01-20
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Stepping Back and Forward on Sumo Folding Evolution
To be Published
5AQ0
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THE STRUCTURE OF THE TRANSTHYRETIN-LIKE DOMAIN OF THE FIRST CATALYTIC DOMAIN OF THE HUMAN CARBOXYPEPTIDASE D
Descriptor:CARBOXYPEPTIDASE D, GLYCEROL
Authors:Gallego, P., Garcia-Pardo, J., Lorenzo, J., Aviles, F.X., Ventura, S., Reverter, D.
Deposit date:2015-09-18
Release date:2016-09-28
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:The Structure of the Ttldomain of the Human Carboxypeptidase D
To be Published
5FW7
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STRUCTURE OF HUMAN TRANSTHYRETIN MUTANT A109V
Descriptor:TRANSTHYRETIN
Authors:Gallego, P., Varejao, N., Santanna, R., Saraiva, M.J., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW8
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STRUCTURE OF HUMAN TRANSTHYRETIN MUTANT E89K
Descriptor:TRANSTHYRETIN
Authors:Gallego, P., Varejao, N., Santanna, R., Saraiva, M.J., Ventura, S., Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
1E6G
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A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
Descriptor:SPECTRIN ALPHA CHAIN, SULFATE ION
Authors:Vega, M.C., Serrano, L.
Deposit date:2000-08-15
Release date:2002-05-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6H
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A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2000-08-17
Release date:2002-05-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1H8K
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A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
Descriptor:SPECTRIN ALPHA CHAIN
Authors:Vega, M.C., Serrano, L.
Deposit date:2001-02-09
Release date:2002-05-23
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
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