Author results

1DSZ
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STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1
Descriptor:DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*G)-3'), RETINOIC ACID RECEPTOR ALPHA, ...
Authors:Rastinejad, F., Wagner, T., Zhao, Q., Khorasanizadeh, S.
Deposit date:2000-01-10
Release date:2000-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
EMBO J., 19, 2000
2NLL
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RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Descriptor:DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*GP*AP*AP*AP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (RETINOIC ACID RECEPTOR), ...
Authors:Rastinejad, F., Perlmann, T., Evans, R.M., Sigler, P.B.
Deposit date:1996-11-20
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of nuclear receptor assembly on DNA direct repeats.
Nature, 375, 1995
2AF9
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, OLEIC ACID, MYRISTIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-25
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG2
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, CHLORIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG4
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CRYSTAL STRUCTURE ANALYSIS OF GM2-ACTIVATOR PROTEIN COMPLEXED WITH PHOSPHATIDYLCHOLINE
Descriptor:Ganglioside GM2 activator, (7R)-4,7-DIHYDROXY-N,N,N-TRIMETHYL-10-OXO-3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM 4-OXIDE, OLEIC ACID, ...
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AG9
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CRYSTAL STRUCTURE OF THE Y137S MUTANT OF GM2-ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator, ISOPROPYL ALCOHOL, MYRISTIC ACID
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
2AGC
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CRYSTAL STRUCTURE OF MOUSE GM2- ACTIVATOR PROTEIN
Descriptor:Ganglioside GM2 activator, MYRISTIC ACID, LAURIC ACID
Authors:Wright, C.S., Mi, L.Z., Lee, S., Rastinejad, F.
Deposit date:2005-07-26
Release date:2005-10-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure Analysis of Phosphatidylcholine-GM2-Activator Product Complexes: Evidence for Hydrolase Activity.
Biochemistry, 44, 2005
1GA5
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CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
Descriptor:5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*(5IT)P*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ...
Authors:Sierk, M.L., Zhao, Q., Rastinejad, F.
Deposit date:2000-11-29
Release date:2001-11-16
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:DNA Deformability as a Recognition Feature in the RevErb Response Element
Biochemistry, 40, 2001
1HLZ
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CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
Descriptor:5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ...
Authors:Sierk, M.L., Zhao, Q., Rastinejad, F.
Deposit date:2000-12-04
Release date:2001-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Deformability as a Recognition Feature in the RevErb Response Element
Biochemistry, 40, 2001
1A62
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CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE TRANSCRIPTIONAL TERMINATOR PROTEIN RHO
Descriptor:RHO
Authors:Allison, T.J., Wood, T.C., Briercheck, D.M., Rastinejad, F., Richardson, J.P., Rule, G.S.
Deposit date:1998-03-05
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the RNA-binding domain from transcription termination factor rho.
Nat.Struct.Biol., 5, 1998
1A6Y
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REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*(5IT)P*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3'), ORPHAN NUCLEAR RECEPTOR NR1D1, ...
Authors:Zhao, Q., Khorasanizadeh, S., Rastinejad, F.
Deposit date:1998-03-04
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural elements of an orphan nuclear receptor-DNA complex.
Mol.Cell, 1, 1998
1BY4
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STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA
Descriptor:DNA (5'-D(*C*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*A)-3'), PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA), ...
Authors:Zhao, Q., Chasse, S.A., Devarakonda, S., Sierk, M.L., Ahvazi, B., Sigler, P.B., Rastinejad, F.
Deposit date:1998-10-22
Release date:2000-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of RXR-DNA interactions.
J.Mol.Biol., 296, 2000
1G13
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HUMAN GM2 ACTIVATOR STRUCTURE
Descriptor:GANGLIOSIDE M2 ACTIVATOR PROTEIN, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Wright, C.S., Li, S.C., Rastinejad, F.
Deposit date:2000-10-10
Release date:2001-04-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human GM2-activator protein with a novel beta-cup topology.
J.Mol.Biol., 304, 2000
1MT6
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9 WITH ADOHCY
Descriptor:SET9, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-20
Release date:2002-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1MUF
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STRUCTURE OF HISTONE H3 K4-SPECIFIC METHYLTRANSFERASE SET7/9
Descriptor:SET9
Authors:Jacobs, S.A., Harp, J.M., Devarakonda, S., Kim, Y., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2002-09-23
Release date:2002-11-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The active site of the SET domain is constructed on a knot
Nat.Struct.Biol., 9, 2002
1OSV
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STRUCTURAL BASIS FOR BILE ACID BINDING AND ACTIVATION OF THE NUCLEAR RECEPTOR FXR
Descriptor:Bile acid receptor, Nuclear receptor coactivator 2, 6-ETHYL-CHENODEOXYCHOLIC ACID
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-20
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1OT7
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STRUCTURAL BASIS FOR 3-DEOXY-CDCA BINDING AND ACTIVATION OF FXR
Descriptor:Bile Acid Receptor, dodecamer peptide fragment of RPGR-interacting protein 1, 6-ETHYL-CHENODEOXYCHOLIC ACID, ...
Authors:Mi, L.Z., Devarakonda, S., Harp, J.M., Han, Q., Pellicciari, R., Willson, T.M., Khorasanizadeh, S., Rastinejad, F.
Deposit date:2003-03-21
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Bile Acid Binding and Activation of the Nuclear Receptor FXR
Mol.Cell, 11, 2003
1P9P
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THE CRYSTAL STRUCTURE OF A M1G37 TRNA METHYLTRANSFERASE, TRMD
Descriptor:tRNA (Guanine-N(1)-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Elkins, P.A., Watts, J.M., Zalacain, M., Van Thiel, A., Vitaszka, P.R., Redlak, M., Andraos-Selim, C., Rastinejad, F., Holmes, W.M.
Deposit date:2003-05-12
Release date:2004-05-18
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into Catalysis by a Knotted TrmD tRNA Methyltransferase.
J.Mol.Biol., 333, 2003
1PU5
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GM2-ACTIVATOR PROTEIN CRYSTAL STRUCTURE
Descriptor:Ganglioside GM2 activator, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Wright, C.S., Zhao, Q., Rastinejad, F.
Deposit date:2003-06-24
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of lipid complexes of GM2-activator protein.
J.Mol.Biol., 331, 2003
1PUB
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GM2-ACTIVATOR PROTEIN CRYSTAL STRUCTURE
Descriptor:GM2-activator protein, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE
Authors:Wright, C.S., Zhao, Q., Rastinejad, F.
Deposit date:2003-06-24
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural analysis of lipid complexes of GM2-activator protein.
J.Mol.Biol., 331, 2003
1R0N
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CRYSTAL STRUCTURE OF HETERODIMERIC ECDSYONE RECEPTOR DNA BINDING COMPLEX
Descriptor:Ecdsyone Response Element, Ecdysone Response Element, Retinoic acid receptor RXR-alpha, ...
Authors:Devarakonda, S., Harp, J.M., Kim, Y., Ozyhar, A., Rastinejad, F.
Deposit date:2003-09-22
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the heterodimeric Ecdysone Receptor DNA-binding complex
Embo J., 22, 2003
1R0O
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CRYSTAL STRUCTURE OF THE HETERODIMERIC ECDYSONE RECEPTOR DNA-BINDING COMPLEX
Descriptor:Ecdysone Response Element, Ultraspiracle protein, Ecdysone receptor, ...
Authors:Devarakonda, S., Harp, J.M., Kim, Y., Ozyhar, A., Rastinejad, F.
Deposit date:2003-09-22
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structure of the Heterodimeric Ecdysone Receptor DNA-binding Complex
Embo J., 22, 2003
1TJJ
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HUMAN GM2 ACTIVATOR PROTEIN PAF COMPLEX
Descriptor:Ganglioside GM2 activator, ACETATE ION, CHLORIDE ION, ...
Authors:Wright, C.S., Mi, L.-Z., Rastinejad, F.
Deposit date:2004-06-04
Release date:2004-12-07
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor
J.Mol.Biol., 342, 2004
2B2T
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND PHOSPHOTHREONINE 3
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3 tail
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
2B2U
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TANDEM CHROMODOMAINS OF HUMAN CHD1 COMPLEXED WITH HISTONE H3 TAIL CONTAINING TRIMETHYLLYSINE 4 AND DIMETHYLARGININE 2
Descriptor:Chromodomain-helicase-DNA-binding protein 1, Histone H3
Authors:Flanagan IV, J.F., Mi, L.-Z., Chruszcz, M., Cymborowski, M., Clines, K.L., Kim, Y., Minor, W., Rastinejad, F., Khorasanizadeh, S.
Deposit date:2005-09-19
Release date:2005-12-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
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