2NLL

RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA

Summary for 2NLL

DescriptorDNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*GP*AP*AP*AP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (RETINOIC ACID RECEPTOR), ... (6 entities in total)
Functional Keywordscomplex (transcription regulation-dna), dna-binding, nuclear protein, zinc- finger, multigene family, alternative splicing, receptor, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P19793 P10828
Total number of polymer chains4
Total molecular weight31357.99
Authors
Rastinejad, F.,Perlmann, T.,Evans, R.M.,Sigler, P.B. (deposition date: 1996-11-20, release date: 1997-03-12, Last modification date: 2011-07-13)
Primary citation
Rastinejad, F.,Perlmann, T.,Evans, R.M.,Sigler, P.B.
Structural determinants of nuclear receptor assembly on DNA direct repeats.
Nature, 375:203-211, 1995
PubMed: 7746322 (PDB entries with the same primary citation)
DOI: 10.1038/375203a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers184.2%11.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2nll
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Molmil generated image of 2nll
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Molmil generated image of 2nll
rotated about y axis by 90°