Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 250 |
| Chain | Residue |
| A | CYS135 |
| A | CYS138 |
| A | CYS152 |
| A | CYS155 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 251 |
| Chain | Residue |
| A | CYS171 |
| A | CYS177 |
| A | CYS187 |
| A | CYS190 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 450 |
| Chain | Residue |
| B | CYS306 |
| B | CYS320 |
| B | CYS323 |
| B | CYS303 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 451 |
| Chain | Residue |
| B | CYS341 |
| B | CYS347 |
| B | CYS357 |
| B | CYS360 |
Functional Information from PROSITE/UniProt
| site_id | PS00031 |
| Number of Residues | 27 |
| Details | NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CvvCg.Dkatgy.HYrcitCegCkgFFrR |
| Chain | Residue | Details |
| B | CYS303-ARG329 | |
| A | CYS135-ARG161 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 139 |
| Details | DNA binding: {"description":"Nuclear receptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00407","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 88 |
| Details | Zinc finger: {"description":"NR C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00407","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Region: {"description":"Nuclear localization signal","evidences":[{"source":"PubMed","id":"12145331","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10669605","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BY4","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine; by EP300","evidences":[{"source":"PubMed","id":"17761950","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"7746322","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2NLL","evidenceCode":"ECO:0007744"}]} |
