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6T59
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STRUCTURE OF RABBIT 80S RIBOSOME TRANSLATING BETA-TUBULIN IN COMPLEX WITH TETRATRICOPEPTIDE PROTEIN 5 AND NASCENT CHAIN-ASSOCIATED COMPLEX
Descriptor:Ribosomal protein L8, uL3, uL4, ...
Authors:Lin, Z., Gasic, I., Chandrasekaran, V., Peters, N., Shao, S., Ramakrishnan, V., Mitchison, T.J., Hegde, R.S.
Deposit date:2019-10-15
Release date:2019-11-27
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:TTC5 mediates autoregulation of tubulin via mRNA degradation.
Science, 367, 2020
6SGC
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RABBIT 80S RIBOSOME STALLED ON A POLY(A) TAIL
Descriptor:18S ribosomal RNA, uS2, 40S ribosomal protein S3a, ...
Authors:Chandrasekaran, V., Juszkiewicz, S., Choi, J., Puglisi, J.D., Brown, A., Shao, S., Ramakrishnan, V., Hegde, R.S.
Deposit date:2019-08-03
Release date:2019-12-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat.Struct.Mol.Biol., 26, 2019
6QG6
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL D)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL C)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL B)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG2
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL A)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG1
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 2)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG0
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 1)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6Q9A
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STRUCTURE OF TMRNA SMPB BOUND PAST E SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q98
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STRUCTURE OF TMRNA SMPB BOUND IN P SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q97
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STRUCTURE OF TMRNA SMPB BOUND IN A SITE OF E. COLI 70S RIBOSOME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6Q95
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STRUCTURE OF TMRNA SMPB BOUND IN A SITE OF T. THERMOPHILUS 70S RIBOSOME
Descriptor:16S RIBOSOMAL RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rae, C.D.
Deposit date:2018-12-17
Release date:2019-02-27
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:How a circularized tmRNA moves through the ribosome.
Science, 363, 2019
6HCQ
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STRUCTURE OF THE RABBIT COLLIDED DI-RIBOSOME (COLLIDED MONOSOME)
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S.
Deposit date:2018-08-16
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCM
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STRUCTURE OF THE RABBIT COLLIDED DI-RIBOSOME (STALLED MONOSOME)
Descriptor:18S ribosomal RNA, uS2, 40S ribosomal protein S3a, ...
Authors:Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCJ
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STRUCTURE OF THE RABBIT 80S RIBOSOME ON GLOBIN MRNA IN THE ROTATED STATE WITH A/P AND P/E TRNAS
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6HCF
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STRUCTURE OF THE RABBIT 80S RIBOSOME STALLED ON GLOBIN MRNA AT THE STOP CODON
Descriptor:18S ribosomal RNA, uS2, 40S ribosomal protein S3a, ...
Authors:Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
6GSN
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION
Descriptor:18S rRNA (1798-MER), KLLA0F09812p, KLLA0D08305p, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published
6GSM
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN CONFORMATION
Descriptor:Met-tRNAi, 18S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published
6FYY
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C2)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYX
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C1)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
5OOM
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STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA
Descriptor:16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ...
Authors:Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V.
Deposit date:2017-08-08
Release date:2017-09-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
5OOL
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STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA
Descriptor:16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ...
Authors:Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V.
Deposit date:2017-08-08
Release date:2017-09-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
5NWX
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INSIGHT INTO THE MOLECULAR RECOGNITION MECHANISM OF THE COACTIVATOR NCOA1 BY STAT6
Descriptor:Nuclear receptor coactivator 1, Signal transducer and activator of transcription 6
Authors:Russo, L., Giller, K., Pfitzner, E., Griesinger, C., Becker, S.
Deposit date:2017-05-08
Release date:2017-12-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6.
Sci Rep, 7, 2017
5MRF
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STRUCTURE OF THE YEAST MITOCHONDRIAL RIBOSOME - CLASS C
Descriptor:21S ribosomal RNA, uL2m, uL3m, ...
Authors:Desai, N., Brown, A., Amunts, A., Ramakrishnan, V.
Deposit date:2016-12-22
Release date:2017-02-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.97 Å)
Cite:The structure of the yeast mitochondrial ribosome.
Science, 355, 2017
5MRE
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STRUCTURE OF THE YEAST MITOCHONDRIAL RIBOSOME - CLASS B
Descriptor:21S ribosomal RNA, uL2m, uL3m, ...
Authors:Desai, N., Brown, A., Amunts, A., Ramakrishnan, V.
Deposit date:2016-12-22
Release date:2017-02-15
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:The structure of the yeast mitochondrial ribosome.
Science, 355, 2017