4WT8

Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex

This is a large structure.

Summary for 4WT8

Integrates4WUS 4WWE 4WWT
DescriptormRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... (67 entities in total)
Functional Keywordsribosome
Biological sourceThermus thermophilus
Total number of polymer chains117
Total molecular weight4460697.04
Authors
Amunts, A.,Fiedorczuk, K.,Ramakrishnan, V. (deposition date: 2014-10-29, release date: 2015-01-21, Last modification date: 2018-07-18)
Primary citation
Amunts, A.,Fiedorczuk, K.,Truong, T.T.,Chandler, J.,Peter Greenberg, E.,Ramakrishnan, V.
Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics.
J.Mol.Biol., 427:753-755, 2015
PubMed: 25562208 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2014.12.018
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.24196.9%14.1%4.7%0.39MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4wt8
no rotation
Molmil generated image of 4wt8
rotated about x axis by 90°
Molmil generated image of 4wt8
rotated about y axis by 90°