4WT8
Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A2 | mRNA | polymer | 9 | 2840.8 | 1 | Thermus thermophilus | ||
2 | AA, BA | 30S ribosomal protein S2 | polymer | 234 | 26987.3 | 2 | UniProt (P80371) Pfam (PF00318) In PDB | Thermus thermophilus | |
3 | AC | 30S ribosomal protein S3 | polymer | 238 | 26622.0 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB | Thermus thermophilus | |
4 | AD, BD | 30S ribosomal protein S4 | polymer | 208 | 24242.3 | 2 | UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB | Thermus thermophilus | |
5 | AE, BE | 30S ribosomal protein S5 | polymer | 150 | 16331.1 | 2 | UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) In PDB | Thermus thermophilus | |
6 | AF, BF | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 2 | UniProt (Q5SLP8) Pfam (PF01250) In PDB | Thermus thermophilus | TS9 |
7 | AG, BG | 30S ribosomal protein S7 | polymer | 155 | 17919.8 | 2 | UniProt (P17291) Pfam (PF00177) In PDB | Thermus thermophilus | |
8 | AH, BH | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 2 | UniProt (Q5SHQ2) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9) In PDB | Thermus thermophilus | |
9 | AI, BI | 30S ribosomal protein S9 | polymer | 127 | 14298.5 | 2 | UniProt (P62669) UniProt (P80374) Pfam (PF00380) In PDB | Thermus thermophilus | |
10 | AJ, BJ | 30S ribosomal protein S10 | polymer | 98 | 11299.2 | 2 | UniProt (Q5SHN7) Pfam (PF00338) In PDB | Thermus thermophilus | |
11 | AK, BK | 30S ribosomal protein S11 | polymer | 119 | 12606.4 | 2 | UniProt (P80376) Pfam (PF00411) In PDB | Thermus thermophilus | |
12 | AL, BL | 30S ribosomal protein S12 | polymer | 124 | 13804.3 | 2 | UniProt (Q5SHN3) Pfam (PF00164) In PDB | Thermus thermophilus | |
13 | AM, BM | 30S ribosomal protein S13 | polymer | 124 | 14078.5 | 2 | UniProt (P80377) Pfam (PF00416) In PDB | Thermus thermophilus | |
14 | AN, BN | 30S ribosomal protein S14 type Z | polymer | 60 | 7027.5 | 2 | UniProt (Q5SHQ1) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6) In PDB | Thermus thermophilus | |
15 | AO, BO | 30S ribosomal protein S15 | polymer | 88 | 10447.2 | 2 | UniProt (Q5SJ76) Pfam (PF00312) In PDB | Thermus thermophilus | |
16 | AP, BP | 30S ribosomal protein S16 | polymer | 83 | 9924.5 | 2 | UniProt (Q5SJH3) Pfam (PF00886) In PDB | Thermus thermophilus | |
17 | AR, BR | 30S ribosomal protein S17 | polymer | 99 | 11722.9 | 2 | UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7) In PDB | Thermus thermophilus | |
18 | AS, BS | 30S ribosomal protein S18 | polymer | 70 | 8155.8 | 2 | UniProt (Q5SLQ0) Pfam (PF01084) In PDB | Thermus thermophilus | |
19 | AT, BT | 30S ribosomal protein S19 | polymer | 78 | 8949.4 | 2 | UniProt (Q5SHP2) Pfam (PF00203) In PDB | Thermus thermophilus | |
20 | AU, BU | 30S ribosomal protein S20 | polymer | 99 | 10921.1 | 2 | UniProt (P80380) Pfam (PF01649) In PDB | Thermus thermophilus | |
21 | AW, BW | 30S ribosomal protein Thx | polymer | 24 | 2960.5 | 2 | UniProt (Q5SIH3) Pfam (PF17070) In PDB | Thermus thermophilus | S31 |
22 | Ab, Bb | RNA (1504-MER) | polymer | 1504 | 488391.2 | 2 | GenBank (55771382) GenBank (155076) | Thermus thermophilus | |
23 | B2 | mRNA | polymer | 10 | 3170.0 | 1 | Thermus thermophilus | ||
24 | BC | 30S ribosomal protein S3 | polymer | 206 | 22862.4 | 1 | UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB | Thermus thermophilus | |
25 | C2, C3, D3 | A site tNA, E site tNA | polymer | 76 | 24485.5 | 3 | Thermus thermophilus | ||
26 | C4 | P site trNA | polymer | 77 | 24802.8 | 1 | Thermus thermophilus | ||
27 | CA | 50S ribosomal protein L1 | polymer | 206 | 19880.5 | 1 | UniProt (Q5SLP7) Pfam (PF00687) In PDB | Thermus thermophilus | |
28 | CB, DB | 50S ribosomal protein L2 | polymer | 271 | 29828.6 | 2 | UniProt (P60405) Pfam (PF00181) Pfam (PF03947) In PDB | Thermus thermophilus | |
29 | CC, DC | 50S ribosomal protein L3 | polymer | 204 | 22250.0 | 2 | UniProt (Q5SHN8) Pfam (PF00297) In PDB | Thermus thermophilus | |
30 | CD, DD | 50S ribosomal protein L4 | polymer | 207 | 23014.7 | 2 | UniProt (Q5SHN9) Pfam (PF00573) In PDB | Thermus thermophilus | L1e |
31 | CE, DE | 50S ribosomal protein L5 | polymer | 181 | 20930.4 | 2 | UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673) In PDB | Thermus thermophilus | |
32 | CF, DF | 50S ribosomal protein L6 | polymer | 159 | 17363.1 | 2 | UniProt (Q5SHQ3) Pfam (PF00347) UniProt (by SIFTS) (P0DOY8) In PDB | Thermus thermophilus | |
33 | CI, DI | 50S ribosomal protein L9 | polymer | 145 | 16093.9 | 2 | UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948) In PDB | Thermus thermophilus | |
34 | CJ, DJ | ribosomal L10 protein | polymer | 130 | 11081.7 | 2 | Thermus thermophilus | ||
35 | CM, DM | 50S ribosomal protein L13 | polymer | 138 | 15699.7 | 2 | UniProt (P60488) Pfam (PF00572) In PDB | Thermus thermophilus | |
36 | CN, DN | 50S ribosomal protein L14 | polymer | 122 | 13323.6 | 2 | UniProt (Q5SHP8) Pfam (PF00238) In PDB | Thermus thermophilus | |
37 | CO, DO | 50S ribosomal protein L15 | polymer | 146 | 15858.5 | 2 | UniProt (Q5SHQ7) Pfam (PF00828) In PDB | Thermus thermophilus | |
38 | CP, DP | 50S ribosomal protein L16 | polymer | 141 | 15993.9 | 2 | UniProt (P60489) Pfam (PF00252) In PDB | Thermus thermophilus | |
39 | CQ, DQ | 50S ribosomal protein L17 | polymer | 117 | 13619.0 | 2 | UniProt (Q9Z9H5) UniProt (Q72I33) Pfam (PF01196) In PDB | Thermus thermophilus | |
40 | CR, DR | 50S ribosomal protein L18 | polymer | 98 | 10941.9 | 2 | UniProt (Q5SHQ4) Pfam (PF00861) In PDB | Thermus thermophilus | TL24 |
41 | CS, DS | 50S ribosomal protein L19 | polymer | 137 | 16218.8 | 2 | UniProt (P60490) Pfam (PF01245) In PDB | Thermus thermophilus | |
42 | CT, DT | 50S ribosomal protein L20 | polymer | 117 | 13572.0 | 2 | UniProt (P60491) Pfam (PF00453) In PDB | Thermus thermophilus | |
43 | CU, DU | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 2 | UniProt (P60492) Pfam (PF00829) In PDB | Thermus thermophilus | |
44 | CW | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 1 | UniProt (Q5SHP3) Pfam (PF00237) In PDB | Thermus thermophilus | |
45 | CX, DX | 50S ribosomal protein L23 | polymer | 92 | 10273.1 | 2 | UniProt (Q5SHP0) Pfam (PF00276) In PDB | Thermus thermophilus | |
46 | CY, DY | 50S ribosomal protein L24 | polymer | 100 | 11078.5 | 2 | UniProt (Q5SHP9) Pfam (PF00467) Pfam (PF17136) In PDB | Thermus thermophilus | |
47 | CZ, DZ | 50S ribosomal protein L25 | polymer | 176 | 19892.9 | 2 | UniProt (Q5SHZ1) Pfam (PF01386) Pfam (PF14693) In PDB | Thermus thermophilus | TL5 |
48 | Ca, Da | 50S ribosomal protein L27 | polymer | 84 | 9397.9 | 2 | UniProt (P60493) Pfam (PF01016) In PDB | Thermus thermophilus | |
49 | CH, DH | 50S ribosomal protein L28 | polymer | 93 | 10458.4 | 2 | UniProt (Q72G84) UniProt (P60494) Pfam (PF00830) In PDB | Thermus thermophilus | |
50 | CK, DK | 50S ribosomal protein L29 | polymer | 71 | 8539.1 | 2 | UniProt (Q5SHP6) Pfam (PF00831) In PDB | Thermus thermophilus | |
51 | CL, DL | 50S ribosomal protein L30 | polymer | 59 | 6670.0 | 2 | UniProt (Q5SHQ6) Pfam (PF00327) In PDB | Thermus thermophilus | |
52 | C5, D5 | 50S ribosomal protein L31 | polymer | 30 | 3278.9 | 2 | UniProt (Q5SJE1) Pfam (PF01197) In PDB | Thermus thermophilus | |
53 | C6, D6 | 50S ribosomal protein L32 | polymer | 59 | 6590.9 | 2 | UniProt (P80339) Pfam (PF01783) In PDB | Thermus thermophilus | |
54 | C7, D7 | 50S ribosomal protein L33 | polymer | 44 | 5473.4 | 2 | UniProt (P35871) Pfam (PF00471) In PDB | Thermus thermophilus | |
55 | C8, D8 | 50S ribosomal protein L34 | polymer | 48 | 5975.3 | 2 | UniProt (P80340) Pfam (PF00468) In PDB | Thermus thermophilus | |
56 | C9, D9 | 50S ribosomal protein L35 | polymer | 63 | 7245.9 | 2 | UniProt (Q5SKU1) Pfam (PF01632) In PDB | Thermus thermophilus | |
57 | C0, D0 | 50S ribosomal protein L36 | polymer | 36 | 4304.2 | 2 | UniProt (Q5SHR2) Pfam (PF00444) In PDB | Thermus thermophilus | Ribosomal protein B |
58 | C1, D1 | 23S rRNA (2899-MER) | polymer | 2899 | 942978.4 | 2 | Thermus thermophilus | ||
59 | Cs, Ds | 5S rRNA (119-MER) | polymer | 119 | 38553.0 | 2 | GenBank (55771382) | Thermus thermophilus | |
60 | D2 | tRNA (5'-D(*AP*UP*CP*CP*CP*CP*GP*UP*GP*UP*CP*CP*UP*UP*GP*GP*UP*UP*CP*G)-3') | polymer | 20 | 6289.7 | 1 | Thermus thermophilus | ||
61 | D4 | tRNA (76-MER) | polymer | 76 | 24497.6 | 1 | Thermus thermophilus | ||
62 | DA | 50S ribosomal protein L1 | polymer | 206 | 19866.5 | 1 | UniProt (Q5SLP7) Pfam (PF00687) In PDB | Thermus thermophilus | |
63 | DW | 50S ribosomal protein L22 | polymer | 113 | 12750.0 | 1 | UniProt (Q5SHP3) Pfam (PF00237) In PDB | Thermus thermophilus | |
64 | DV | DNA (55-MER) | polymer | 55 | 17821.7 | 1 | Thermus thermophilus | ||
65 | Ab, Bb | PAROMOMYCIN | non-polymer | 615.6 | 2 | Chemie (PAR) | |||
66 | C1, D1 | Bactobolin A | non-polymer | 381.3 | 2 | Chemie (3V6) | |||
67 | C1, D1 | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
AI, BI: 2 - 128 (UniProt: P80374)
Ab, Bb: 6 - 1509 (GenBank: 55771382)
CA: 18 - 110 (UniProt: Q5SLP7)
CA: 119 - 233 (PDB: 4WT8)
CQ, DQ: 2 - 118 (UniProt: Q9Z9H5)
CT, DT: 2 - 118 (UniProt: P60491)
CH, DH: 3 - 95 (UniProt: Q72G84)
Cs, Ds: 1 - 119 (PDB: 4WT8)
DA: 18 - 110 (UniProt: Q5SLP7)
DA: 119 - 233 (PDB: 4WT8)
DW: 1 - 112 (UniProt: Q5SHP3)
PDB | External Database | Details |
---|---|---|
Arg 58 | His 58 | conflict |
CA: 18 - 110 (UniProt: Q5SLP7)
PDB | External Database | Details |
---|---|---|
Ala 106 | Gly 107 | conflict |
CQ, DQ: 2 - 118 (UniProt: Q9Z9H5)
CT, DT: 2 - 118 (UniProt: P60491)
PDB | External Database | Details |
---|---|---|
Ala 32 | Phe 32 | conflict |
Cs, Ds: 1 - 119 (PDB: 4WT8)
DA: 18 - 110 (UniProt: Q5SLP7)
DA: 119 - 233 (PDB: 4WT8)
DW: 1 - 112 (UniProt: Q5SHP3)
PDB | External Database | Details |
---|---|---|
Ala 113 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 117 |
Total formula weight | 4458654.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2042.4 | |
All* | Total formula weight | 4460697.0 |