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1ALI
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BU of 1ali by Molmil
ALKALINE PHOSPHATASE MUTANT (H412N)
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-06-02
Release date:1995-11-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
1ALJ
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BU of 1alj by Molmil
ALKALINE PHOSPHATASE MUTANT (H412N)
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ma, L, Tibbitts, T.T, Kantrowitz, E.R.
Deposit date:1995-06-02
Release date:1995-11-14
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Escherichia coli alkaline phosphatase: X-ray structural studies of a mutant enzyme (His-412-->Asn) at one of the catalytically important zinc binding sites.
Protein Sci., 4, 1995
1HQA
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BU of 1hqa by Molmil
ALKALINE PHOSPHATASE (H412Q)
Descriptor: ALKALINE PHOSPHATASE, ZINC ION
Authors:Ma, L, Kantrowitz, E.R.
Deposit date:1995-11-30
Release date:1996-03-08
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Kinetic and X-ray structural studies of a mutant Escherichia coli alkaline phosphatase (His-412-->Gln) at one of the zinc binding sites.
Biochemistry, 35, 1996
1FA4
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BU of 1fa4 by Molmil
ELUCIDATION OF THE PARAMAGNETIC RELAXATION OF HETERONUCLEI AND PROTONS IN CU(II) PLASTOCYANIN FROM ANABAENA VARIABILIS
Descriptor: COPPER (II) ION, PLASTOCYANIN
Authors:Ma, L, Jorgensen, A.M, Sorensen, G.O, Ulstrup, J, Led, J.J.
Deposit date:2000-07-12
Release date:2000-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Elucidation of the Paramagnetic R1 Relaxation of Heteronuclei and Protons in Cu(II) Plastocyanin from Anabaena Variabilis
J.Am.Chem.Soc., 122, 2000
1R6R
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BU of 1r6r by Molmil
Solution Structure of Dengue Virus Capsid Protein Reveals a New Fold
Descriptor: Genome polyprotein
Authors:Ma, L, Jones, C.T, Groesch, T.D, Kuhn, R.J, Post, C.B.
Deposit date:2003-10-16
Release date:2004-02-17
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of dengue virus capsid protein reveals another fold
Proc.Natl.Acad.Sci.USA, 101, 2004
6K8I
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BU of 6k8i by Molmil
Crystal structure of Arabidopsis thaliana CRY2
Descriptor: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Ma, L, Wang, X, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
8DK4
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BU of 8dk4 by Molmil
Peroxisome proliferator-activated receptor gamma in complex with VSP-51-2
Descriptor: 5-(benzylcarbamoyl)-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Authors:Ma, L, Zhou, X.E, Suino-Powell, K, Hou, N, Zhou, Z, Luo, J, Xu, H.E, Yi, W.
Deposit date:2022-07-02
Release date:2023-07-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of VSP-51-2 as the Novel and Safe PPAR gamma Modulator: Structure-Based Design, Biological Validation and Crystal Analysis
To Be Published
6M79
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BU of 6m79 by Molmil
Cryo-EM structure of Arabidopsis CRY under blue light-mediated activation
Descriptor: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Ma, L, Guan, Z.Y, Yin, P.
Deposit date:2020-03-18
Release date:2020-10-14
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the photoactivation of Arabidopsis CRY2.
Nat.Plants, 6, 2020
7XTQ
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BU of 7xtq by Molmil
Cryo-EM structure of the R399-bound GPBAR-Gs complex
Descriptor: G-protein coupled bile acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Ma, L, Yang, F, Wu, X, Mao, C, Sun, J, Yu, X, Zhang, Y, Zhang, P.
Deposit date:2022-05-17
Release date:2022-07-06
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VJS
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BU of 7vjs by Molmil
Human AlkB homolog ALKBH6 in complex with Tris and Ni
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, NICKEL (II) ION
Authors:Ma, L, Chen, Z.
Deposit date:2021-09-28
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6.
J.Biol.Chem., 298, 2022
7VJV
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BU of 7vjv by Molmil
Human AlkB homolog ALKBH6 in complex with alpha-katoglutarate and Mn
Descriptor: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6, MANGANESE (II) ION
Authors:Ma, L, Chen, Z.
Deposit date:2021-09-29
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6.
J.Biol.Chem., 298, 2022
5WLX
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BU of 5wlx by Molmil
Solution structure of kappa-theraphotoxin-Aa1a
Descriptor: Kappa-theraphotoxin-Aa1a
Authors:Chin, Y.K.Y, Ma, L, King, G.F.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
6K8K
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BU of 6k8k by Molmil
Crystal structure of Arabidopsis thaliana BIC2-CRY2 complex
Descriptor: ADENOSINE MONOPHOSPHATE, Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Wang, X, Ma, L, Guan, Z, Yin, P.
Deposit date:2019-06-12
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into BIC-mediated inactivation of Arabidopsis cryptochrome 2.
Nat.Struct.Mol.Biol., 27, 2020
8IFF
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BU of 8iff by Molmil
Cryo-EM structure of Arabidopsis phytochrome A.
Descriptor: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A
Authors:Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P.
Deposit date:2023-02-17
Release date:2023-08-02
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Plant phytochrome A in the Pr state assembles as an asymmetric dimer.
Cell Res., 33, 2023
4ORB
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BU of 4orb by Molmil
Crystal structure of mouse calcineurin
Descriptor: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ...
Authors:Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.108 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
4ORC
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BU of 4orc by Molmil
Crystal structure of mammalian calcineurin
Descriptor: CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ...
Authors:Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
2KKZ
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BU of 2kkz by Molmil
Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R].
Descriptor: Non-structural protein NS1
Authors:Aramini, J.M, Ma, L, Lee, H, Zhao, L, Cunningham, K, Ciccosanti, C, Janjua, H, Fang, Y, Xiao, R, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-29
Release date:2009-07-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution NMR structure of the monomeric W187R mutant of A/Udorn NS1 effector domain. Northeast Structural Genomics target OR8C[W187R].
To be Published
3KB2
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BU of 3kb2 by Molmil
Crystal Structure of YorR protein in complex with phosphorylated GDP from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR256
Descriptor: GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, MAGNESIUM ION, SPBc2 prophage-derived uncharacterized protein yorR
Authors:Forouhar, F, Friedman, D, Seetharaman, J, Janjua, J, Xiao, R, Cunningham, K, Ma, L, Ho, C, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-20
Release date:2009-10-27
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Northeast Structural Genomics Consortium Target SR256
To be Published
5XF1
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BU of 5xf1 by Molmil
Structure of the Full-length glucagon class B G protein-coupled receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B.
Deposit date:2017-04-06
Release date:2017-05-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure of the full-length glucagon class B G-protein-coupled receptor.
Nature, 546, 2017
9J23
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BU of 9j23 by Molmil
Structure of a triple-helix region of human Collagen type II from Trautec
Descriptor: Triple-helix region of human collagen type II
Authors:Fan, X, Zhai, Y, Chu, Y, Fu, S, Li, D, Feng, P, Cao, K, Li, J, Si, Y, Ma, L, Qian, S.
Deposit date:2024-08-06
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of a triple-helix region of human Collagen type II from Trautec
To Be Published
9J26
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BU of 9j26 by Molmil
Structure of a triple-helix region of human Collagen type IV from Trautec
Descriptor: Triple-helix region of human collagen type IV
Authors:Fan, X, Zhai, Y, Chu, Y, Fu, S, Li, D, Cao, K, Feng, P, Wu, X, Cai, H, Ma, L, Qian, S.
Deposit date:2024-08-06
Release date:2024-08-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of a triple-helix region of human Collagen type IV from Trautec
To Be Published
6F02
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BU of 6f02 by Molmil
Crystal structure of human glycosylated kallistatin at 3.0 Angstrom resolution
Descriptor: Kallistatin, SULFATE ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Zhou, A, Ma, L.
Deposit date:2017-11-17
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human Kallistatin
To Be Published
3KVP
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BU of 3kvp by Molmil
Crystal Structure of Uncharacterized protein ymzC Precursor from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR378A
Descriptor: ACETIC ACID, Uncharacterized protein ymzC
Authors:Kuzin, A.P, Chen, Y, Seetharaman, J, Afonine, P, Fang, F, Xiao, R, Cunningham, K, Ma, L, Chen, C.X, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-11-30
Release date:2010-02-02
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Northeast Structural Genomics Consortium Target SR378A
To be Published
3LM6
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BU of 3lm6 by Molmil
Crystal Structure of Stage V sporulation protein AD (spoVAD) from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR525
Descriptor: Stage V sporulation protein AD
Authors:Forouhar, F, Su, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-01-29
Release date:2010-02-16
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Northeast Structural Genomics Consortium Target SR525
To be Published
1NY1
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BU of 1ny1 by Molmil
CRYSTAL STRUCTURE OF B. SUBTILIS POLYSACCHARIDE DEACETYLASE NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR127.
Descriptor: Probable polysaccharide deacetylase pdaA
Authors:Forouhar, F, Edstrom, W, Khan, J, Ma, L, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-02-11
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Polysaccharide Deacetylase (PDAA_BACSU) from B. Subtilis (Pdaa_Bacsu) Northeast Structural Genomics Research Consortium (Nesg) Target Sr127
To be Published

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