8DK4

Peroxisome proliferator-activated receptor gamma in complex with VSP-51-2

Summary for 8DK4

• Entry DOI: 10.2210/pdb8dk4/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, 5-(benzylcarbamoyl)-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid, ... (4 entities in total)
• Functional Keywords: peroxisome proliferator-activated receptor gamma, modulator, vsp-51-2, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 33125.93

Authors

Ma, L.,Zhou, X.E.,Suino-Powell, K.,Hou, N.,Zhou, Z.,Luo, J.,Xu, H.E.,Yi, W. (deposition date: 2022-07-02, release date: 2023-07-05, Last modification date: 2023-10-25)

• Primary citation: Ma, L.,Zhou, X.E.,Suino-Powell, K.,Hou, N.,Zhou, Z.,Luo, J.,Xu, H.E.,Yi, W.; Identification of VSP-51-2 as the Novel and Safe PPAR gamma Modulator: Structure-Based Design, Biological Validation and Crystal Analysis; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.6 Å)