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5VD6
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CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH BISUBSTRATE ANALOG 6
Descriptor:acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,23S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14-dioxo-23-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatetracosan-24-oic acid 3,5-dioxide (non-preferred name)
Authors:Majorek, K.A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
5VDB
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CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH BISUBSTRATE ANALOG 3
Descriptor:acetyltransferase PA4794, SULFATE ION, (3R,5S,9R,26S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,20-trioxo-26-({[(phenylacetyl)amino]acetyl}amino)-2,4,6-trioxa-18-thia-11,15,21-triaza-3,5-diphosphaheptacosan-27-oic acid 3,5-dioxide (non-preferred name)
Authors:Majorek, K.A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2017-04-01
Release date:2017-07-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
FEBS Lett., 591, 2017
6BZY
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE 22D11 BROADLY NEUTRALIZING ANTIBODY
Descriptor:22D11 Heavy Chain, 22D11 Light Chain, E2 AS412 peptide
Authors:Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4N0Y
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STRUCTURE OF THE HEPATITIS C ENVELOPE GLYCOPROTEIN E1 ANTIGENIC REGION 314-324 BOUND TO THE CROSS-NEUTRALIZING ANTIBODY IGH526
Descriptor:IGH526 Heavy Chain, IGH526 Light Chain, HCV E1 peptide, ...
Authors:Kong, L., Wilson, I.A.
Deposit date:2013-10-02
Release date:2015-04-01
Last modified:2015-08-26
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structure of Hepatitis C Virus Envelope Glycoprotein E1 Antigenic Site 314-324 in Complex with Antibody IGH526.
J.Mol.Biol., 427, 2015
4EVY
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE ANTIBIOTIC 6'-N-ACETYLTRANSFERASE AAC(6')-IG FROM ACINETOBACTER HAEMOLYTICUS IN COMPLEX WITH TOBRAMYCIN
Descriptor:Aminoglycoside N(6')-acetyltransferase type 1, TOBRAMYCIN, POTASSIUM ION, ...
Authors:Stogios, P.J., Evdokimova, E., Minasov, G., Yim, V., Courvalin, P., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-04-26
Release date:2012-05-09
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (1.768 Å)
Cite:Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
4DGY
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HCV1, C2 FORM
Descriptor:HCV1 Heavy Chain, HCV1 Light Chain, E2 peptide, ...
Authors:Kong, L., Wilson, I.A., Law, M.
Deposit date:2012-01-27
Release date:2012-05-23
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DGV
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HCV1, P2(1) FORM
Descriptor:HCV1 Heavy Chain, HCV1 Light Chain, E2 peptide, ...
Authors:Kong, L., Wilson, I.A., Law, M.
Deposit date:2012-01-26
Release date:2012-05-23
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (1.805 Å)
Cite:Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E8O
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE ANTIBIOTIC 6'-N-ACETYLTRANSFERASE AAC(6')-IH FROM ACINETOBACTER BAUMANNII
Descriptor:Aac(6')-Ih protein, CHLORIDE ION
Authors:Stogios, P.J., Minasov, G., Dong, A., Evdokimova, E., Yim, V., Courvalin, P., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-03-20
Release date:2012-04-04
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.138 Å)
Cite:Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
6BZW
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE GL PRECURSOR OF THE BROADLY NEUTRALIZING ANTIBODY AP33
Descriptor:AP33 GL Heavy Chain, AP33 GL Light Chain, E2 AS412 peptide
Authors:Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4G6A
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY AP33
Descriptor:E2 peptide, AP33 Heavy Chain, AP33 Light chain
Authors:Kong, L., Wilson, I.A., Law, M.
Deposit date:2012-07-18
Release date:2012-09-26
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33.
J.Virol., 86, 2012
4F0Y
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE ANTIBIOTIC 6'-N-ACETYLTRANSFERASE AAC(6')-IG FROM ACINETOBACTER HAEMOLYTICUS, APO
Descriptor:Aminoglycoside N(6')-acetyltransferase type 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Stogios, P.J., Evdokimova, E., Dong, A., Minasov, G., Yim, V., Courvalin, P., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-05-05
Release date:2012-05-16
Last modified:2017-02-22
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
ACS Infect Dis., 3, 2017
6BKC
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3B
Descriptor:Fab AR3B heavy chain, Fab AR3B light chain, Polyprotein, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019
4MWF
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3C
Descriptor:Fab AR3C heavy chain, Fab AR3C light chain, Envelope glycoprotein E2, ...
Authors:Kong, L., Wilson, I.A., Law, M.
Deposit date:2013-09-24
Release date:2013-12-11
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:Hepatitis C virus e2 envelope glycoprotein core structure.
Science, 342, 2013
6BZV
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE GL PRECURSOR OF THE BROADLY NEUTRALIZING ANTIBODY 19B3
Descriptor:19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide
Authors:Tzarum, N., Alemn, F., Wilson, I.A., Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.654 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BZU
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STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY 19B3
Descriptor:19B3 Heavy Chain, 19B3 Light Chain, E2 AS412 peptide
Authors:Tzarum, N., Alemn, F., Kong, L., Wilson, I.A., Law, M.
Deposit date:2017-12-26
Release date:2018-06-20
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BKB
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3A
Descriptor:Fab AR3A heavy chain, Polyprotein, Fab AR3A light chain, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019
6BKD
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STRUCTURE OF HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 CORE FROM GENOTYPE 6A BOUND TO BROADLY NEUTRALIZING ANTIBODY AR3D
Descriptor:Polyprotein, Fab AR3D heavy chain, Fab AR3D light chain, ...
Authors:Tzarum, N., Wilson, I.A., Law, M.
Deposit date:2017-11-08
Release date:2018-12-26
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structures of HCV genotype 6 E2 core and human VH1-69 broadly neutralizing antibodies
Sci Adv, 2019