Author results

1AVG
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THROMBIN INHIBITOR FROM TRIATOMA PALLIDIPENNIS
Descriptor:THROMBIN, TRIABIN
Authors:Fuentes-Prior, P., Huber, R., Bode, W.
Deposit date:1997-09-16
Release date:1998-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug.
Proc.Natl.Acad.Sci.USA, 94, 1997
1DX5
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CRYSTAL STRUCTURE OF THE THROMBIN-THROMBOMODULIN COMPLEX
Descriptor:Thrombin light chain, Thrombomodulin, Thrombin heavy chain, ...
Authors:Fuentes-Prior, P., Iwanaga, Y., Huber, R., Pagila, R., Rumennik, G., Seto, M., Morser, J., Light, D.R., Bode, W.
Deposit date:1999-12-20
Release date:2000-04-10
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
1E0F
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CRYSTAL STRUCTURE OF THE HUMAN ALPHA-THROMBIN-HAEMADIN COMPLEX: AN EXOSITE II-BINDING INHIBITOR
Descriptor:THROMBIN, HAEMADIN
Authors:Richardson, J.L., Kroeger, B., Hoefken, W., Pereira, P., Huber, R., Bode, W., Fuentes-Prior, P.
Deposit date:2000-03-27
Release date:2000-11-03
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor
Embo J., 19, 2000
1NU7
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STAPHYLOCOAGULASE-THROMBIN COMPLEX
Descriptor:Thrombin light chain, Thrombin heavy chain, Staphylocoagulase, ...
Authors:Friedrich, R., Bode, W., Fuentes-Prior, P., Panizzi, P., Bock, P.E.
Deposit date:2003-01-31
Release date:2003-10-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
NATURE, 425, 2003
1NU9
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STAPHYLOCOAGULASE-PRETHROMBIN-2 COMPLEX
Descriptor:Thrombin light and heavy chains, Staphylocoagulase, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Friedrich, R., Bode, W., Fuentes-Prior, P., Panizzi, P., Bock, P.E.
Deposit date:2003-01-31
Release date:2003-10-07
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation
NATURE, 425, 2003
2A1D
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STAPHYLOCOAGULASE BOUND TO BOVINE THROMBIN
Descriptor:thrombin, Staphylocoagulase, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Friedrich, R., Panizzi, P., Kawabata, S., Bode, W., Bock, P.E., Fuentes-Prior, P.
Deposit date:2005-06-20
Release date:2005-09-27
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis for Reduced Staphylocoagulase-mediated Bovine Prothrombin Activation
J.Biol.Chem., 281, 2006
1CZS
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: COMPLEX WITH PHENYLMERCURY
Descriptor:PROTEIN (COAGULATION FACTOR V), PHENYLMERCURY
Authors:Macedo-Ribeiro, S., Bode, W., Huber, R., Kane, W.H., Fuentes-Prior, P.
Deposit date:1999-09-07
Release date:1999-11-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
1CZT
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V
Descriptor:PROTEIN (COAGULATION FACTOR V)
Authors:Macedo-Ribeiro, S., Bode, W., Huber, R., Kane, W.H., Fuentes-Prior, P.
Deposit date:1999-09-07
Release date:1999-11-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
1CZV
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CRYSTAL STRUCTURE OF THE C2 DOMAIN OF HUMAN COAGULATION FACTOR V: DIMERIC CRYSTAL FORM
Descriptor:PROTEIN (COAGULATION FACTOR V)
Authors:Macedo-Ribeiro, S., Bode, W., Huber, R., Kane, W.H., Fuentes-Prior, P.
Deposit date:1999-09-07
Release date:1999-11-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the membrane-binding C2 domain of human coagulation factor V.
Nature, 402, 1999
1FQ3
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CRYSTAL STRUCTURE OF HUMAN GRANZYME B
Descriptor:GRANZYME B, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Estebanez-Perpina, E., Fuentes-Prior, P., Belorgey, D., Rubin, H., Bode, W.
Deposit date:2000-09-03
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue.
Biol.Chem., 381, 2000
1GQF
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CRYSTAL STRUCTURE OF HUMAN PROCASPASE-7
Descriptor:Caspase-7, SULFATE ION
Authors:Riedl, S., Bode, W., Fuentes-Prior, P.
Deposit date:2001-11-23
Release date:2002-01-04
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for the activation of human procaspase-7.
Proc. Natl. Acad. Sci. U.S.A., 98, 2001
1GT9
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HIGH RESOLUTION CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE-CARBOXYL TYPE PROTEINASE, KUMAMOLISIN (KSCP)
Descriptor:KUMAMOLYSIN, CALCIUM ION, SULFATE ION
Authors:Comellas-Bigler, M., Fuentes-Prior, P., Maskos, K., Huber, R., Oyama, H., Uchida, K., Dunn, B.M., Oda, K., Bode, W.
Deposit date:2002-01-14
Release date:2002-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase
Structure, 10, 2002
1GTG
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CRYSTAL STRUCTURE OF THE THERMOSTABLE SERINE-CARBOXYL TYPE PROTEINASE, KUMAMOLYSIN (KSCP)
Descriptor:KUMAMOLYSIN, CALCIUM ION
Authors:Comellas-Bigler, M., Fuentes-Prior, P., Maskos, K., Huber, R., Oyama, H., Uchida, K., Dunn, B.M., Oda, K., Bode, W.
Deposit date:2002-01-15
Release date:2002-06-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase
Structure, 10, 2002
1GTJ
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CRYSTAL STRUCTURE OF THE THERMOSTABLE SERINE-CARBOXYL TYPE PROTEINASE, KUMAMOLISIN (KSCP) - COMPLEX WITH AC-ILE-ALA-PHE-CHO
Descriptor:KUMAMOLYSIN, ALDEHYDE INHIBITOR, SULFATE ION, ...
Authors:Comellas-Bigler, M., Fuentes-Prior, P., Maskos, K., Huber, R., Oyama, H., Uchida, K., Dunn, B.M., Oda, K., Bode, W.
Deposit date:2002-01-15
Release date:2002-06-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase
Structure, 10, 2002
1GTL
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THE THERMOSTABLE SERINE-CARBOXYL TYPE PROTEINASE, KUMAMOLISIN (KSCP) - COMPLEX WITH AC-ILE-PRO-PHE-CHO
Descriptor:KUMAMOLYSIN, ALDEHYDE INHIBITOR, CALCIUM ION, ...
Authors:Comellas-Bigler, M., Fuentes-Prior, P., Maskos, K., Huber, R., Oyama, H., Uchida, K., Dunn, B.M., Oda, K., Bode, W.
Deposit date:2002-01-16
Release date:2002-06-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase
Structure, 10, 2002
1JC9
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TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB)
Descriptor:techylectin-5A, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
Authors:Kairies, N., Beisel, H.-G., Fuentes-Prior, P., Tsuda, R., Muta, T., Iwanaga, S., Bode, W., Huber, R., Kawabata, S.
Deposit date:2001-06-08
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems.
Proc.Natl.Acad.Sci.USA, 98, 2001
1MZA
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CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYME K
Descriptor:pro-granzyme K
Authors:Hink-Schauer, C., Estebanez-Perpina, E., Wilharm, E., Fuentes-Prior, P., Klinkert, W., Bode, W., Jenne, D.E.
Deposit date:2002-10-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:The 2.2-A Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features
J.BIOL.CHEM., 277, 2002
1MZD
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CRYSTAL STRUCTURE OF HUMAN PRO-GRANZYME K
Descriptor:pro-granzyme K
Authors:Hink-Schauer, C., Estebanez-Perpina, E., Wilharm, E., Fuentes-Prior, P., Klinkert, W., Bode, W., Jenne, D.E.
Deposit date:2002-10-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The 2.2-A Crystal Structure of Human Pro-granzyme K Reveals a Rigid Zymogen with Unusual Features
J.BIOL.CHEM., 277, 2002
2ODY
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THROMBIN-BOUND BOOPHILIN DISPLAYS A FUNCTIONAL AND ACCESSIBLE REACTIVE-SITE LOOP
Descriptor:Prothrombin (EC 3.4.21.5), Boophilin, PHOSPHATE ION, ...
Authors:Macedo-Ribeiro, S., Fuentes-Prior, P., Pereira, P.J.B.
Deposit date:2006-12-27
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
Plos One, 3, 2008
3P6Z
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STRUCTURAL BASIS OF THROMBIN MEDIATED FACTOR V ACTIVATION: ESSENTIAL ROLE OF THE HIRUDIN-LIKE SEQUENCE GLU666-GLU672 FOR PROCESSING AT THE HEAVY CHAIN-B DOMAIN JUNCTION
Descriptor:Thrombin light chain, Thrombin heavy chain, Coagulation factor V, ...
Authors:Corral-Rodriguez, M.A., Bock, P.E., Hernandez-Carvajal, E., Gutierrez-Gallego, R., Fuentes-Prior, P.
Deposit date:2010-10-11
Release date:2011-06-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Blood, 117, 2011
3P70
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STRUCTURAL BASIS OF THROMBIN-MEDIATED FACTOR V ACTIVATION: ESSENTIAL ROLE OF THE HIRUDIN-LIKE SEQUENCE GLU666-GLU672 FOR PROCESSING AT THE HEAVY CHAIN-B DOMAIN JUNCTION
Descriptor:HUMAN ALPHA-THROMBIN, LIGHT CHAIN, HEAVY CHAIN, ...
Authors:Corral-Rodriguez, M.A., Bock, P.E., Hernandez-Carvajal, E., Gutierrez-Gallego, R., Fuentes-Prior, P.
Deposit date:2010-10-11
Release date:2011-09-28
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Blood, 117, 2011
4E05
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ANOPHELIN FROM THE MALARIA VECTOR INHIBITS THROMBIN THROUGH A NOVEL REVERSE-BINDING MECHANISM
Descriptor:Thrombin, Salivary anti-thrombin peptide anophelin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Figueiredo, A.C., de Sanctis, D., Gutierrez-Gallego, R., Cereija, T.B., Macedo-Ribeiro, S., Fuentes-Prior, P., Pereira, P.J.B.
Deposit date:2012-03-02
Release date:2012-12-05
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E06
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ANOPHELIN FROM THE MALARIA VECTOR INHIBITS THROMBIN THROUGH A NOVEL REVERSE-BINDING MECHANISM
Descriptor:Thrombin, Salivary anti-thrombin peptide anophelin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Figueiredo, A.C., de Sanctis, D., Gutierrez-Gallego, R., Cereija, T.B., Macedo-Ribeiro, S., Fuentes-Prior, P., Pereira, P.J.B.
Deposit date:2012-03-02
Release date:2012-12-05
Last modified:2013-01-09
Method:X-RAY DIFFRACTION (3.196 Å)
Cite:Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector.
Proc.Natl.Acad.Sci.USA, 109, 2012
5JJM
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CRYSTAL STRUCTURE OF HOMODIMERIC ANDROGEN RECEPTOR LIGAND-BINDING DOMAIN BOUND TO DHT AND LXXLL PEPTIDE
Descriptor:Androgen receptor, Unknown peptide, uba3-derived peptide, ...
Authors:Estebanez-Perpina, E., Fuentes-Prior, P.
Deposit date:2016-04-24
Release date:2017-03-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure of the homodimeric androgen receptor ligand-binding domain.
Nat Commun, 8, 2017
1EAW
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CRYSTAL STRUCTURE OF THE MTSP1 (MATRIPTASE)-BPTI (APROTININ) COMPLEX
Descriptor:SUPPRESSOR OF TUMORIGENICITY 14, PANCREATIC TRYPSIN INHIBITOR
Authors:Friedrich, R., Bode, W.
Deposit date:2001-07-17
Release date:2002-01-28
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase.
J.Biol.Chem., 277, 2002
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