Author results

2QFB
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CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN RIG-I WITH BOUND ZN
分子名称:Probable ATP-dependent RNA helicase DDX58, ZINC ION
著者Cui, S., Lammens, A., Lammens, K., Hopfner, K.P.
登録日2007-06-27
公開日2008-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
2QFD
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CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN RIG-I WITH BOUND HG
分子名称:Probable ATP-dependent RNA helicase DDX58, MERCURY (II) ION
著者Cui, S., Lammens, A., Lammens, K., Hopfner, K.P.
登録日2007-06-27
公開日2008-02-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I.
Mol.Cell, 29, 2008
3EIK
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DOUBLE STRANDED DNA BINDING PROTEIN
分子名称:TATA-box-binding protein, 1,2-ETHANEDIOL
著者Cui, S., Wollmann, P., Moldt, M., Hopfner, K.-P.
登録日2008-09-16
公開日2009-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献structural studies of ecTBP
To be Published
3OCI
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CRYSTAL STRUCTURE OF TBP (TATA BOX BINDING PROTEIN)
分子名称:TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 1,2-ETHANEDIOL
著者Cui, S., Wollmann, P., Moldt, M., Hopfner, K.-P.
登録日2010-08-10
公開日2011-07-13
最終更新日2015-01-14
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
3OSY
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HUMAN ENTEROVIRUS 71 3C PROTEASE
分子名称:3C protease
著者Wang, J., Fan, T., Wang, M., Cui, S.
登録日2010-09-10
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9923 Å)
主引用文献Crystal Structure of Human Enterovirus 71 3C Protease.
J.Mol.Biol., 408, 2011
2W4R
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CRYSTAL STRUCTURE OF THE REGULATORY DOMAIN OF HUMAN LGP2
分子名称:PROBABLE ATP-DEPENDENT RNA HELICASE DHX58, MERCURY (II) ION, SULFATE ION
著者Pippig, D.A., Hellmuth, J.C., Cui, S., Kirchhofer, A., Lammens, K., Lammens, A., Schmidt, A., Rothenfusser, S., Hopfner, K.P.
登録日2008-12-01
公開日2009-02-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Regulatory Domain of the Rig-I Family ATPase Lgp2 Senses Double-Stranded RNA.
Nucleic Acids Res., 37, 2009
3G9A
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GREEN FLUORESCENT PROTEIN BOUND TO MINIMIZER NANOBODY
分子名称:Green fluorescent protein, Minimizer
著者Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U.
登録日2009-02-13
公開日2009-12-08
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (1.614 Å)
主引用文献Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
3K1K
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GREEN FLUORESCENT PROTEIN BOUND TO ENHANCER NANOBODY
分子名称:Green Fluorescent Protein, Enhancer
著者Kirchhofer, A., Helma, J., Schmidthals, K., Frauer, C., Cui, S., Karcher, A., Pellis, M., Muyldermans, S., Delucci, C.C., Cardoso, M.C., Leonhardt, H., Hopfner, K.-P., Rothbauer, U.
登録日2009-09-28
公開日2009-12-08
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Modulation of protein properties in living cells using nanobodies
Nat.Struct.Mol.Biol., 17, 2010
3VGX
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STRUCTURE OF GP41 T21/CP621-652
分子名称:Envelope glycoprotein gp160, ACETIC ACID, GLYCEROL
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2011-08-22
公開日2012-04-25
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Discovery of critical residues for viral entry and inhibition through structural Insight of HIV-1 fusion inhibitor CP621-652.
J.Biol.Chem., 287, 2012
3VGY
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P321
分子名称:Envelope glycoprotein gp160, CP32M, SULFATE ION
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-08-22
公開日2012-06-13
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.034 Å)
主引用文献Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VH7
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STRUCTURE OF HIV-1 GP41 NHR/FUSION INHIBITOR COMPLEX P21
分子名称:Envelope glycoprotein gp160, CP32M, MAGNESIUM ION
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-08-23
公開日2012-06-13
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.019 Å)
主引用文献Structural basis of potent and broad HIV-1 fusion inhibitor CP32M
J.Biol.Chem., 287, 2012
3VIE
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HIV-GP41 FUSION INHIBITOR SIFUVIRTIDE
分子名称:Envelope glycoprotein gp160, Sifuvirtide
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2011-09-29
公開日2012-01-18
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Broad antiviral activity and crystal structure of HIV-1 fusion inhibitor sifuvirtide
J.Biol.Chem., 287, 2012
3VTP
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HIV FUSION INHIBITOR MT-C34
分子名称:Transmembrane protein gp41
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2012-06-02
公開日2012-08-22
最終更新日2014-01-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The M-T hook structure is critical for design of HIV-1 fusion inhibitors.
J.Biol.Chem., 287, 2012
3VTQ
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NOVEL HIV FUSION INHIBITOR
分子名称:Envelope glycoprotein gp160, fusion inhibitor MT-Sifuvirtide
著者Yao, X., Waltersperger, S., Wang, M., Cui, S.
登録日2012-06-02
公開日2013-06-26
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Crystal structure of a novel HIV fusion inhibitor
To be Published
3VU5
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SHORT PEPTIDE HIV ENTRY INHIBITOR SC22EK
分子名称:Transmembrane protein gp41, SC22, SULFATE ION, ...
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-06-19
公開日2012-12-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VU6
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SHORT PEPTIDE HIV ENTRY INHIBITOR MT-SC22EK WITH A M-T HOOK
分子名称:Transmembrane protein gp41, MTSC22, SULFATE ION
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-06-19
公開日2012-12-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2.324 Å)
主引用文献Short-peptide fusion inhibitors with high potency against wild-type and enfuvirtide-resistant HIV-1
Faseb J., 27, 2013
3VWB
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN (SE-MET DERIVATIVE) COMPLEXED WITH THE CIS-ACTING SITE (5-BRU MODIFICATIONS) UPSTREAM ICSB PROMOTER
分子名称:Virulence regulon transcriptional activator virB, DNA (26-MER)
著者Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
登録日2012-08-21
公開日2013-08-21
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (2.416 Å)
主引用文献Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W19
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POTENT HIV FUSION INHIBITOR CP32M-2
分子名称:Transmembrane protein gp41, fusion inhibitor CP32M-2
著者Yao, X., Waltersperger, S., Wang, M.T., Cui, S.
登録日2012-11-13
公開日2013-12-11
実験手法X-RAY DIFFRACTION (1.278 Å)
主引用文献Optimization of novel anti-HIV fusion inhibitor
To be Published
3W2A
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSP PROMOTER
分子名称:Virulence regulon transcriptional activator VirB, DNA (31-mer)
著者Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
登録日2012-11-27
公開日2013-09-04
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (2.775 Å)
主引用文献Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
3W3C
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CRYSTAL STRUCTURE OF VIRB CORE DOMAIN COMPLEXED WITH THE CIS-ACTING SITE UPSTREAM ICSB PROMOTER
分子名称:Virulence regulon transcriptional activator VirB, DNA (26-MER)
著者Gao, X.P., Waltersperger, S., Wang, M.T., Cui, S.
登録日2012-12-19
公開日2013-09-04
最終更新日2013-12-25
実験手法X-RAY DIFFRACTION (2.431 Å)
主引用文献Structural insights into VirB-DNA complexes reveal mechanism of transcriptional activation of virulence genes
Nucleic Acids Res., 41, 2013
4I2L
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NEW HIV ENTRY INHIBITOR MTSFT/T23 COMPLEX
分子名称:GP41, inhibitor MTSFT
著者Yao, X., Chong, H.H., Waltersperger, S., Wang, M.T., He, Y.X., Cui, S.
登録日2012-11-22
公開日2014-01-22
実験手法X-RAY DIFFRACTION (1.426 Å)
主引用文献Potent antiviral activity of the novel HIV entry inhibitor MTSFT
To be Published
5GMQ
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STRUCTURE OF MERS-COV RBD IN COMPLEX WITH A FULLY HUMAN ANTIBODY MCA1
分子名称:S protein, MCA1 heavy chain, MCA1 light chain, ...
著者Chen, C., Wang, J.M., Zou, T.T., Gao, X.P., Cui, S., Jin, Q.
登録日2016-07-15
公開日2017-05-31
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.
J. Infect. Dis., 215, 2017
3OC3
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CRYSTAL STRUCTURE OF THE MOT1 N-TERMINAL DOMAIN IN COMPLEX WITH TBP
分子名称:HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
著者Wollmann, P., Cui, S., Viswanathan, R., Berninghausen, O., Wells, M.N., Moldt, M., Witte, G., Butryn, A., Wendler, P., Beckmann, R., Auble, D.T., Hopfner, K.-P.
登録日2010-08-09
公開日2011-07-13
最終更新日2011-07-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.
Nature, 475, 2011
3QZQ
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71D IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.7001 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
3QZR
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HUMAN ENTEROVIRUS 71 3C PROTEASE MUTANT E71A IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, 1,2-ETHANEDIOL
著者Wang, J., Fan, T., Yao, X., Wu, Z., Guo, L., Lei, X., Wang, J., Wang, M., Jin, Q., Cui, S.
登録日2011-03-07
公開日2011-08-10
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (1.039 Å)
主引用文献Crystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important Residues.
J.Virol., 85, 2011
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