5WWP

Crystal structure of Middle East respiratory syndrome coronavirus helicase (MERS-CoV nsp13)

Summary for 5WWP

DescriptorORF1ab, ZINC ION, SULFATE ION (3 entities in total)
Functional Keywordsmiddle east respiratory syndrome coronavirus, nidovirales, coronavirus, mers, nsp13, helicase, sf1 superfamily, atp hydrolysis, atpase, rna 5'-triphosphatase, unwinding, upf1 helicase, arterivirus nsp10, zinc binding domain, ch domain, 1b beta-barrel domain, viral rna synthesis, reca-like domain, cov replication and transcription, hydrolase
Biological sourceHuman betacoronavirus 2c EMC/2012
Cellular locationHost cytoplasm, host perinuclear region . Host membrane ; Multi-pass membrane protein  K0BWD0
Total number of polymer chains2
Total molecular weight133548.54
Authors
Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S. (deposition date: 2017-01-03, release date: 2017-07-05)
Primary citation
Hao, W.,Wojdyla, J.A.,Zhao, R.,Han, R.,Das, R.,Zlatev, I.,Manoharan, M.,Wang, M.,Cui, S.
Crystal structure of Middle East respiratory syndrome coronavirus helicase
PLoS Pathog., 13:e1006474-e1006474, 2017
PubMed: 28651017 (PDB entries with the same primary citation)
DOI: 10.1371/journal.ppat.1006474
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.283150.9%3.4%1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5wwp
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Molmil generated image of 5wwp
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Molmil generated image of 5wwp
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More Biological unit images

Molmil generated image of 5wwp
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Molmil generated image of 5wwp
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Molmil generated image of 5wwp
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5wwp.pdb1.gz [96.33 KB])
Coordinate files for Biological unit (5wwp.pdb2.gz [84.03 KB])