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1F3F
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STRUCTURE OF THE H122G NUCLEOSIDE DIPHOSPHATE KINASE / D4T-TRIPHOSPHATE.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, ...
Authors:Meyer, P., Schneider, B., Sarfati, S., Deville-Bonne, D., Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B.
Deposit date:2000-06-02
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1F6T
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STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE/ALPHA-BORANO(RP)-TDP.MG COMPLEX
Descriptor:PROTEIN (NUCLEOSIDE DIPHOSPHATE KINASE), MAGNESIUM ION, 2*-DEOXY-THYMIDINE-5*-ALPHA BORANO DIPHOSPHATE (ISOMER RP)
Authors:Guerreiro, C., Boretto, J., Janin, J., Veron, M., Canard, B., Schneider, B., Sarfati, S., Deville-Bonne, D.
Deposit date:2000-06-23
Release date:2000-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
EMBO J., 19, 2000
1L9K
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DENGUE METHYLTRANSFERASE
Descriptor:RNA-DIRECTED RNA POLYMERASE, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Egloff, M.P., Benarroch, D., Selisko, B., Romette, J.L., Canard, B.
Deposit date:2002-03-25
Release date:2003-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:An RNA cap (nucleoside-2'-O-) methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
Embo J., 21, 2002
1MN9
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NDP KINASE MUTANT (H122G) COMPLEX WITH RTP
Descriptor:NDP kinase, MAGNESIUM ION, RIBAVIRIN TRIPHOSPHATE
Authors:Gallois-montbrun, S., Chen, Y., Dutartre, H., Morera, S., Guerreiro, C., Mulard, L., Schneider, B., Janin, J., Canard, B., Veron, M., Deville-bonne, D.
Deposit date:2002-09-05
Release date:2003-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
MOL.PHARMACOL., 63, 2003
1OKS
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CRYSTAL STRUCTURE OF THE MEASLES VIRUS PHOSPHOPROTEIN XD DOMAIN
Descriptor:RNA POLYMERASE ALPHA SUBUNIT, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
Authors:Johansson, K., Bourhis, J.-M., Campanacci, V., Cambillau, C., Canard, B., Longhi, S.
Deposit date:2003-07-29
Release date:2003-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Measles Virus Phosphoprotein Domain Responsible for the Induced Folding of the C-Terminal Domain of the Nucleoprotein
J.Biol.Chem., 278, 2003
1QZ8
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS NSP9
Descriptor:polyprotein 1ab, SULFATE ION
Authors:Egloff, M.P., Ferron, F., Campanacci, V., Longhi, S., Rancurel, C., Dutartre, H., Snijder, E.J., Gorbalenya, A.E., Cambillau, C., Canard, B.
Deposit date:2003-09-16
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world.
Proc.Natl.Acad.Sci.USA, 101, 2004
1R6A
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STRUCTURE OF THE DENGUE VIRUS 2'O METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYL HOMOCYSTEINE AND RIBAVIRIN 5' TRIPHOSPHATE
Descriptor:Genome polyprotein, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Benarroch, D., Egloff, M.P., Mulard, L., Romette, J.L., Canard, B.
Deposit date:2003-10-15
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate.
J.Biol.Chem., 279, 2004
2CKW
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THE 2.3 A RESOLUTION STRUCTURE OF THE SAPPORO VIRUS RNA DEPENDANT RNA POLYMERASE.
Descriptor:RNA-DIRECTED RNA POLYMERASE
Authors:Fullerton, S.W.B., Tucker, P.A., Rohayem, J., Coutard, B., Gebhardt, J., Gorbalenya, A., Canard, B.
Deposit date:2006-04-24
Release date:2006-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase.
J.Virol., 81, 2007
2FAV
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CRYSTAL STRUCTURE OF SARS MACRO DOMAIN IN COMPLEX WITH ADP-RIBOSE AT 1.8 A RESOLUTION
Descriptor:Replicase polyprotein 1ab (pp1ab) (ORF1AB), ADENOSINE-5-DIPHOSPHORIBOSE
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2005-12-08
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.
J.Virol., 80, 2006
2H85
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CRYSTAL STRUCTURE OF NSP 15 FROM SARS
Descriptor:Putative orf1ab polyprotein
Authors:Ricagno, S., Egloff, M.P., Ulferts, R., Coutard, B., Nurizzo, D., Campanacci, V., Cambillau, C., Ziebuhr, J., Canard, B.
Deposit date:2006-06-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2HCN
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), CALCIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-17
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HCS
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CRYSTAL STRUCTURE OF RNA DEPENDANT RNA POLYMERASE DOMAIN OF WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase (NS5), ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-18
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2HFZ
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CRYSTAL STRUCTURE OF RNA DEPENDENT RNA POLYMERASE DOMAIN FROM WEST NILE VIRUS
Descriptor:RNA-directed RNA polymerase(NS5), MAGNESIUM ION, ZINC ION
Authors:Egloff, M.P., Malet, H., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2006-06-26
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
J.Biol.Chem., 282, 2007
2J7U
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN
Descriptor:RNA DEPENDENT RNA POLYMERASE, ZINC ION, MAGNESIUM ION, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7W
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN COMPLEXED WITH 3' DGTP
Descriptor:POLYPROTEIN, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2L8K
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NMR STRUCTURE OF THE ARTERIVIRUS NONSTRUCTURAL PROTEIN 7 ALPHA (NSP7 ALPHA)
Descriptor:Non-structural protein 7
Authors:Conte, M.R., Gaudin, C., Manolaridis, I., Tucker, P.W., Kelly, G.
Deposit date:2011-01-19
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Genetic Analysis of the Arterivirus Nonstructural Protein 7{alpha}.
J.Virol., 85, 2011
2OXT
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CRYSTAL STRUCTURE OF MEABAN VIRUS NUCLEOSIDE-2'-O-METHYLTRANSFERASE
Descriptor:NUCLEOSIDE-2'-O-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Mastrangelo, E., Milani, M., Bollati, M., Bolognesi, M.
Deposit date:2007-02-21
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase
Protein Sci., 16, 2007
2P1D
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GTP AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Benarooch, D., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-05
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An RNA cap (nucleoside-2'-O)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
EMBO J., 21, 2002
2P3L
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3O
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P3Q
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH GPPPG AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, DIGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-09
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P40
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG
Descriptor:type II methyltransferase, SULFATE ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2P41
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CRYSTAL STRUCTURE OF DENGUE METHYLTRANSFERASE IN COMPLEX WITH 7MEGPPPG2'OME AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:type II methyltransferase, SULFATE ION, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-GUANOSINE, ...
Authors:Egloff, M.P., Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2007-03-11
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5
J.Mol.Biol., 372, 2007
2QEQ
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CRYSTAL STRUCTURE OF KUNJIN VIRUS NS3 HELICASE
Descriptor:Flavivirin protease NS3 catalytic subunit
Authors:Milani, M., Mastrangelo, E., Bolognesi, M.
Deposit date:2007-06-26
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
J.Mol.Biol., 372, 2007
2V6I
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KOKOBERA VIRUS HELICASE
Descriptor:RNA HELICASE, PYROPHOSPHATE 2-
Authors:Speroni, S., De Colibus, L., Coutard, B., Canard, B., Mattevi, A.
Deposit date:2007-07-18
Release date:2008-03-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008