Author results

1DO0
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ORTHORHOMBIC CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI
Descriptor:PROTEIN (HEAT SHOCK LOCUS U), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bochtler, M., Hartmann, C., Song, H.K., Bourenkov, G.P., Bartunik, H.D.
Deposit date:1999-12-18
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of HsIU and the ATP-dependent protease HsIU-HsIV.
Nature, 403, 2000
1DO2
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TRIGONAL CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI
Descriptor:PROTEIN (HEAT SHOCK LOCUS U), PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Bochtler, M., Hartmann, C., Song, H.K., Bourenkov, G.P., Bartunik, H.D.
Deposit date:1999-12-18
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:The structures of HsIU and the ATP-dependent protease HsIU-HsIV.
Nature, 403, 2000
1NED
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CRYSTAL STRUCTURE OF HSLV (CLPQ) AT 3.8 ANGSTROMS RESOLUTION
Descriptor:HSLV
Authors:Bochtler, M., Ditzel, L., Groll, M., Huber, R.
Deposit date:1997-04-04
Release date:1998-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of heat shock locus V (HslV) from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 94, 1997
2FQZ
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METAL-DEPLETED ECL18KI IN COMPLEX WITH UNCLEAVED DNA
Descriptor:DNA STRAND 1, DNA STRAND 2, R.Ecl18kI
Authors:Bochtler, M., Szczepanowski, R.H., Tamulaitis, G., Grazulis, S., Czapinska, H., Manakova, E., Siksnys, V.
Deposit date:2006-01-18
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease
Embo J., 25, 2006
2GB7
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METAL-DEPLETED ECL18KI IN COMPLEX WITH UNCLEAVED, MODIFIED DNA
Descriptor:DNA STRAND 1, DNA STRAND 2, R.Ecl18kI
Authors:Bochtler, M., Szczepanowski, R.H., Tamulaitis, G., Grazulis, S., Czapinska, H., Manakova, E., Siksnys, V.
Deposit date:2006-03-10
Release date:2006-06-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease
Embo J., 25, 2006
3FUC
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RECOMBINANT CALF PURINE NUCLEOSIDE PHOSPHORYLASE IN A BINARY COMPLEX WITH MULTISUBSTRATE ANALOGUE INHIBITOR 9-(5',5'-DIFLUORO-5'-PHOSPHONOPENTYL)-9-DEAZAGUANINE STRUCTURE IN A NEW SPACE GROUP WITH ONE FULL TRIMER IN THE ASYMMETRIC UNIT
Descriptor:Purine nucleoside phosphorylase, [5-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)-1,1-difluoropentyl]phosphonic acid, MAGNESIUM ION, ...
Authors:Bochtler, M., Breer, K., Bzowska, A., Chojnowski, G., Hashimoto, M., Hikishima, S., Narczyk, M., Wielgus-Kutrowska, B., Yokomatsu, T.
Deposit date:2009-01-14
Release date:2009-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
Biochem.Biophys.Res.Commun., 391, 2010
1Y4H
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WILD TYPE STAPHOPAIN-STAPHOSTATIN COMPLEX
Descriptor:cysteine protease, cysteine protease inhibitor, CHLORIDE ION, ...
Authors:Filipek, R., Potempa, J., Bochtler, M.
Deposit date:2004-11-30
Release date:2005-01-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A comparison of staphostatin B with standard mechanism serine protease inhibitors.
J.Biol.Chem., 280, 2005
3IMB
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ALTERNATIVE BINDING MODE OF RESTRICTION ENDONUCLEASE BCNI TO COGNATE DNA
Descriptor:R.BcnI, 5'-D(*GP*TP*CP*CP*GP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*CP*GP*GP*AP*C)-3'
Authors:Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Szczepanowski, R.H., Siksnys, V., Bochtler, M.
Deposit date:2009-08-10
Release date:2010-08-11
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:How BcnI and MvaI distinguish W from S
To be Published
1E94
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HSLV-HSLU FROM E.COLI
Descriptor:HEAT SHOCK PROTEIN HSLV, HEAT SHOCK PROTEIN HSLU, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Song, H.K., Hartmann, C., Ravishankar, R., Bochtler, M.
Deposit date:2000-10-07
Release date:2000-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutational Studies on Hslu and its Docking Mode with Hslv
Proc.Natl.Acad.Sci.USA, 97, 2000
1TZP
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MEPA, INACTIVE FORM WITHOUT ZN IN P21
Descriptor:Penicillin-insensitive murein endopeptidase, SULFATE ION, 1,4-BUTANEDIOL
Authors:Marcyjaniak, M., Odintsov, S.G., Sabala, I., Bochtler, M.
Deposit date:2004-07-11
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Peptidoglycan amidase MepA is a LAS metallopeptidase
J.Biol.Chem., 279, 2004
1PXV
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THE STAPHOSTATIN-STAPHOPAIN COMPLEX: A FORWARD BINDING INHIBITOR IN COMPLEX WITH ITS TARGET CYSTEINE PROTEASE
Descriptor:cysteine protease, cysteine protease Inhibitor, SULFATE ION, ...
Authors:Filipek, R., Rzychon, M., Oleksy, A., Gruca, M., Dubin, A., Potempa, J., Bochtler, M.
Deposit date:2003-07-07
Release date:2003-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Staphostatin-Staphopain Complex: A FORWARD BINDING INHIBITOR IN COMPLEX WITH ITS TARGET CYSTEINE PROTEASE.
J.Biol.Chem., 278, 2003
1U10
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MEPA, ACTIVE FORM WITH ZN IN P1
Descriptor:Penicillin-insensitive murein endopeptidase, ZINC ION, SULFATE ION
Authors:Marcyjaniak, M., Odintsov, S.G., Sabala, I., Bochtler, M.
Deposit date:2004-07-14
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Peptidoglycan amidase MepA is a LAS metallopeptidase
J.Biol.Chem., 279, 2004
2B0P
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TRUNCATED S. AUREUS LYTM, P212121 CRYSTAL FORM
Descriptor:Glycyl-glycine endopeptidase lytM, ZINC ION, CACODYLATE ION, ...
Authors:Firczuk, M., Mucha, A., Bochtler, M.
Deposit date:2005-09-14
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of active LytM.
J.Mol.Biol., 354, 2005
2B13
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TRUNCATED S. AUREUS LYTM, P41 CRYSTAL FORM
Descriptor:Glycyl-glycine endopeptidase lytM, ZINC ION, L(+)-TARTARIC ACID
Authors:Firczuk, M., Mucha, A., Bochtler, M.
Deposit date:2005-09-15
Release date:2006-01-10
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of active LytM.
J.Mol.Biol., 354, 2005
2OA9
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RESTRICTION ENDONUCLEASE MVAI IN THE ABSENCE OF DNA
Descriptor:R.MvaI, CHLORIDE ION, CADMIUM ION, ...
Authors:Kaus-Drobek, M., Czapinska, H., Sokolowska, M., Tamulaitis, G., Szczepanowski, R.H., Urbanke, K., Siksnys, V., Bochtler, M.
Deposit date:2006-12-15
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically.
Nucleic Acids Res., 35, 2007
2OAA
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RESTRICTION ENDONUCLEASE MVAI-COGNATE DNA SUBSTRATE COMPLEX
Descriptor:5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3', 5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3', R.MvaI, ...
Authors:Kaus-Drobek, M., Czapinska, H., Sokolowska, M., Tamulaitis, G., Szczepanowski, R.H., Urbanke, K., Siksnys, V., Bochtler, M.
Deposit date:2006-12-15
Release date:2007-02-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically.
Nucleic Acids Res., 35, 2007
2ODH
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RESTRICTION ENDONUCLEASE BCNI IN THE ABSENCE OF DNA
Descriptor:R.BcnI, ACETATE ION, DI(HYDROXYETHYL)ETHER
Authors:Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Szczepanowski, R.H., Urbanke, K., Siksnys, V., Bochtler, M.
Deposit date:2006-12-22
Release date:2007-03-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
J.Mol.Biol., 369, 2007
2ODI
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RESTRICTION ENDONUCLEASE BCNI-COGNATE DNA SUBSTRATE COMPLEX
Descriptor:5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3', 5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3', R.BcnI, ...
Authors:Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Szczepanowski, R.H., Urbanke, C., Siksnys, V., Bochtler, M.
Deposit date:2006-12-22
Release date:2007-03-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA.
J.Mol.Biol., 369, 2007
2Q10
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RESTRICTION ENDONUCLEASE BCNI (WILD TYPE)-COGNATE DNA SUBSTRATE COMPLEX
Descriptor:DNA (5'-D(*AP*AP*CP*CP*CP*GP*GP*AP*GP*AP*C)-3'), DNA (5'-D(*CP*TP*CP*CP*GP*GP*GP*TP*TP*GP*T)-3'), R.BcnI, ...
Authors:Sokolowska, M., Kaus-Drobek, M., Czapinska, H., Tamulaitis, G., Szczepanowski, R.H., Urbanke, C., Siksnys, V., Bochtler, M.
Deposit date:2007-05-23
Release date:2007-06-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Monomeric Restriction Endonuclease BcnI in the Apo Form and in an Asymmetric Complex with Target DNA.
J.Mol.Biol., 369, 2007
3BM3
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RESTRICTION ENDONUCLEASE PSPGI-SUBSTRATE DNA COMPLEX
Descriptor:DNA (5'-D(*CP*AP*TP*CP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*GP*GP*TP*AP*CP*CP*TP*GP*GP*AP*T)-3'), PspGI restriction endonuclease, ...
Authors:Szczepanowski, R.H., Carpenter, M., Czapinska, H., Tamulaitis, G., Siksnys, V., Bhagwat, A., Bochtler, M.
Deposit date:2007-12-12
Release date:2008-09-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A direct crystallographic demonstration that Type II restriction endonuclease PspGI flips nucleotides
To be Published
1X9Y
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THE PROSTAPHOPAIN B STRUCTURE
Descriptor:cysteine proteinase
Authors:Filipek, R., Szczepanowski, R., Sabat, A., Potempa, J., Bochtler, M.
Deposit date:2004-08-24
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition.
Biochemistry, 43, 2004
1NYC
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STAPHOSTATINS RESEMBLE LIPOCALINS, NOT CYSTATINS IN FOLD.
Descriptor:cysteine protease inhibitor, CHLORIDE ION, SULFATE ION
Authors:Rzychon, M., Filipek, R., Sabat, A., Kosowska, K., Dubin, A., Potempa, J., Bochtler, M.
Deposit date:2003-02-12
Release date:2003-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Staphostatins resemble lipocalins, not cystatins in fold.
Protein Sci., 12, 2003
1OH1
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SOLUTION STRUCTURE OF STAPHOSTATIN A FORM STAPHYLOCOCCUS AUREUS CONFIRMS THE DISCOVERY OF A NOVEL CLASS OF CYSTEINE PROTEINASE INHIBITORS.
Descriptor:STAPHOSTATIN A
Authors:Dubin, G., Popowicz, G., Krajewski, M., Stec, J., Bochtler, M., Potempa, J., Dubin, A., Holak, T.A.
Deposit date:2003-05-21
Release date:2003-11-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Novel Class of Cysteine Protease Inhibitors: Solution Structure of Staphostatin a from Staphylococcus Aureus
Biochemistry, 42, 2003
1QWY
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LATENT LYTM AT 1.3 A RESOLUTION
Descriptor:peptidoglycan hydrolase, ZINC ION
Authors:Odintsov, S.G., Sabala, I., Marcyjaniak, M., Bochtler, M.
Deposit date:2003-09-03
Release date:2004-01-20
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Latent LytM at 1.3A resolution.
J.Mol.Biol., 335, 2004
1RYP
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CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST AT 2.4 ANGSTROMS RESOLUTION
Descriptor:20S PROTEASOME, MAGNESIUM ION
Authors:Groll, M., Ditzel, L., Loewe, J., Stock, D., Bochtler, M., Bartunik, H.D., Huber, R.
Deposit date:1997-02-26
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of 20S proteasome from yeast at 2.4 A resolution.
Nature, 386, 1997
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