7QGD

H. SAPIENS CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6-DIBROMOBENZOTRIAZOLE AT PH 8.5

Summary for 7QGD

Entry DOI	10.2210/pdb7qgd/pdb
Related	6TLL 6TLP
Descriptor	Casein kinase II subunit alpha, 5,6-DIBROMOBENZOTRIAZOLE, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	ck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-inhibitor complex, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	47319.50
Authors	Winiewska-Szajewska, M.,Czapinska, H.,Kaus-Drobek, M.,Piasecka, A.,Mieczkowska, K.,Dadlez, M.,Bochtler, M.,Poznanski, J. (deposition date: 2021-12-08, release date: 2022-10-19, Last modification date: 2024-01-31)
Primary citation	Winiewska-Szajewska, M.,Czapinska, H.,Kaus-Drobek, M.,Fricke, A.,Mieczkowska, K.,Dadlez, M.,Bochtler, M.,Poznanski, J. Competition between electrostatic interactions and halogen bonding in the protein-ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2 alpha complexes. Sci Rep, 12:18964-18964, 2022 Cited by PubMed: 36347916 DOI: 10.1038/s41598-022-23611-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation