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7QGE

H. SAPIENS CK2 KINASE ALPHA SUBUNIT IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 5,6,7,8-TETRABROMOBENZOTRIAZOLE (TBBt) AT PH 8.5

Summary for 7QGE
Entry DOI10.2210/pdb7qge/pdb
Related6TLL 6TLP
DescriptorCasein kinase II subunit alpha, 4,5,6,7-TETRABROMOBENZOTRIAZOLE, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsck2, casein kinase 2, inhibitor, bromo-benzotriazole, halogen bond, transferase-inhibitor complex, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight46855.98
Authors
Winiewska-Szajewska, M.,Czapinska, H.,Kaus-Drobek, M.,Piasecka, A.,Mieczkowska, K.,Dadlez, M.,Bochtler, M.,Poznanski, J. (deposition date: 2021-12-08, release date: 2022-10-19, Last modification date: 2024-01-31)
Primary citationWiniewska-Szajewska, M.,Czapinska, H.,Kaus-Drobek, M.,Fricke, A.,Mieczkowska, K.,Dadlez, M.,Bochtler, M.,Poznanski, J.
Competition between electrostatic interactions and halogen bonding in the protein-ligand system: structural and thermodynamic studies of 5,6-dibromobenzotriazole-hCK2 alpha complexes.
Sci Rep, 12:18964-18964, 2022
Cited by
PubMed: 36347916
DOI: 10.1038/s41598-022-23611-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

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