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4IF8
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BU of 4if8 by Molmil
Structure Of Vaspin
Descriptor: SULFATE ION, Serpin A12
Authors:Kuettner, E.B, Strater, N, Heiker, J.T, Kloting, N, Kovacs, P, Schultz, S, Kern, M, Stumvoll, M, Bluher, M, Beck-Sickinger, A.G.
Deposit date:2012-12-14
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Vaspin inhibits kallikrein 7 by serpin mechanism
Cell.Mol.Life Sci., 70, 2013
1TZ4
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BU of 1tz4 by Molmil
[hPP19-23]-pNPY bound to DPC Micelles
Descriptor: neuropeptide Y,Pancreatic prohormone,neuropeptide Y
Authors:Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2004-07-09
Release date:2005-07-05
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes in Structure and Membrane Binding
Biochemistry, 44, 2005
1TZ5
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BU of 1tz5 by Molmil
[pNPY19-23]-hPP bound to DPC Micelles
Descriptor: Pancreatic prohormone,neuropeptide Y,Pancreatic prohormone
Authors:Lerch, M, Kamimori, H, Folkers, G, Aguilar, M.I, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2004-07-09
Release date:2005-07-05
Last modified:2020-01-01
Method:SOLUTION NMR
Cite:Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes in Structure and Membrane Binding
Biochemistry, 44, 2005
1ICY
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BU of 1icy by Molmil
[ALA31,PRO32]-PNPY BOUND TO DPC MICELLES
Descriptor: NEUROPEPTIDE Y
Authors:Bader, R, Rytz, G, Lerch, M, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2001-04-02
Release date:2002-05-08
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY.
Biochemistry, 41, 2002
1F8P
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BU of 1f8p by Molmil
PORCINE NEUROPEPTIDE Y BOUND TO DPC MICELLES
Descriptor: NEUROPEPTIDE Y (PNPY)
Authors:Bader, R, Beck-Sickinger, A.G, Zerbe, O.
Deposit date:2000-07-03
Release date:2001-01-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection.
J.Mol.Biol., 305, 2001
1FVN
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BU of 1fvn by Molmil
[ALA31, AIB32]-NEUROPEPTIDE Y
Descriptor: NEUROPEPTIDE Y
Authors:Bader, R, Zerbe, O, Beck-Sickinger, A.G.
Deposit date:2000-09-20
Release date:2000-10-04
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats.
J.Biol.Chem., 275, 2000
7DDZ
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BU of 7ddz by Molmil
The Crystal Structure of Human Neuropeptide Y Y2 Receptor with JNJ-31020028
Descriptor: FLAVIN MONONUCLEOTIDE, Human Neuropeptide Y Y2 Receptor fusion protein, ~{N}-[4-[4-[(1~{S})-2-(diethylamino)-2-oxidanylidene-1-phenyl-ethyl]piperazin-1-yl]-3-fluoranyl-phenyl]-2-pyridin-3-yl-benzamide
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2020-10-30
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for ligand recognition of the neuropeptide Y Y 2 receptor.
Nat Commun, 12, 2021
5ZBQ
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BU of 5zbq by Molmil
The Crystal Structure of human neuropeptide Y Y1 receptor with UR-MK299
Descriptor: Neuropeptide Y receptor type 1,T4 Lysozyme, N~2~-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-N~5~-(N'-{[2-(propanoylamino)ethyl]carbamoyl}carbamimidoyl)-D-ornithinamide
Authors:Yang, Z, Han, S, Zhao, Q, Wu, B.
Deposit date:2018-02-12
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
Nature, 556, 2018
5ZBH
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BU of 5zbh by Molmil
The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885
Descriptor: Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1, dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Authors:Yang, Z, Han, S, Zhao, Q, Wu, B.
Deposit date:2018-02-11
Release date:2018-04-25
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of ligand binding modes at the neuropeptide Y Y1receptor
Nature, 556, 2018
8SG1
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BU of 8sg1 by Molmil
Cryo-EM structure of CMKLR1 signaling complex
Descriptor: CHOLESTEROL, Chemerin 9, Chemerin-like receptor 1, ...
Authors:Zhang, X, Zhang, C.
Deposit date:2023-04-11
Release date:2023-11-01
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis of G protein-Coupled receptor CMKLR1 activation and signaling induced by a chemerin-derived agonist.
Plos Biol., 21, 2023
7X9B
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BU of 7x9b by Molmil
Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7X9C
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BU of 7x9c by Molmil
Cryo-EM structure of neuropeptide Y Y4 receptor in complex with PP and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7X9A
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BU of 7x9a by Molmil
Cryo-EM structure of neuropeptide Y Y1 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Tang, T, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-03-15
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors.
Sci Adv, 8, 2022
7PIU
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BU of 7piu by Molmil
Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
Descriptor: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
7PIV
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BU of 7piv by Molmil
Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.
Descriptor: CALCIUM ION, Camelid antibody VHH fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
5EI0
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BU of 5ei0 by Molmil
Structure of RCL-cleaved vaspin (serpinA12)
Descriptor: Serpin A12
Authors:Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N.
Deposit date:2015-10-29
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of cleaved vaspin (serpinA12).
Biol.Chem., 397, 2016
6SAA
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BU of 6saa by Molmil
M-TRTX-Preg1a (Poecilotheria regalis)
Descriptor: U1-theraphotoxin-Pf3
Authors:Meudal, H, Landon, C, Delmas, A.F.
Deposit date:2019-07-16
Release date:2020-07-22
Last modified:2020-08-26
Method:SOLUTION NMR
Cite:A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
J.Med.Chem., 63, 2020
6SAB
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BU of 6sab by Molmil
M-BUTX-Ptr1a (Parabuthus transvaalicus)
Descriptor: M-BUTX-Ptr1a
Authors:Meudal, H, Landon, C, Delmas, A.F.
Deposit date:2019-07-16
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
J.Med.Chem., 63, 2020
2RMY
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BU of 2rmy by Molmil
Structure of the N-terminal BARpeptide in SDS micelles
Descriptor: Myc box-dependent-interacting protein 1
Authors:Loew, C, Weininger, U, Balbach, J.
Deposit date:2007-12-03
Release date:2008-10-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Biophys.J., 95, 2008
2RND
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BU of 2rnd by Molmil
Structure of the N-terminal BARpeptide in DPC micelles
Descriptor: Myc box-dependent-interacting protein 1
Authors:Loew, C, Weininger, U, Balbach, J.
Deposit date:2007-12-16
Release date:2008-10-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Biophys.J., 95, 2008

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