6SAB

M-BUTX-Ptr1a (Parabuthus transvaalicus)

Summary for 6SAB

• Entry DOI: 10.2210/pdb6sab/pdb
• NMR Information: BMRB: 34418
• Descriptor: M-BUTX-Ptr1a (1 entity in total)
• Functional Keywords: screening, melanocortin receptor, gpcr, animal toxin, toxin
• Biological source: Parabuthus transvaalicus (South African fattail scorpion)
• Total number of polymer chains: 1
• Total formula weight: 3809.74

Authors

Meudal, H.,Landon, C.,Delmas, A.F. (deposition date: 2019-07-16, release date: 2020-07-22, Last modification date: 2023-06-14)

• Primary citation: Reynaud, S.,Ciolek, J.,Degueldre, M.,Saez, N.J.,Sequeira, A.F.,Duhoo, Y.,Bras, J.L.A.,Meudal, H.,Cabo Diez, M.,Fernandez Pedrosa, V.,Verdenaud, M.,Boeri, J.,Pereira Ramos, O.,Ducancel, F.,Vanden Driessche, M.,Fourmy, R.,Violette, A.,Upert, G.,Mourier, G.,Beck-Sickinger, A.G.,Morl, K.,Landon, C.,Fontes, C.M.G.A.,Minambres Herraiz, R.,Rodriguez de la Vega, R.C.,Peigneur, S.,Tytgat, J.,Quinton, L.,De Pauw, E.,Vincentelli, R.,Servent, D.,Gilles, N.; A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.; J.Med.Chem., 63:8250-8264, 2020; PubMed: 32602722; DOI: 10.1021/acs.jmedchem.0c00485

Experimental method

SOLUTION NMR