7DDZ

The Crystal Structure of Human Neuropeptide Y Y2 Receptor with JNJ-31020028

Summary for 7DDZ

Entry DOI	10.2210/pdb7ddz/pdb
Descriptor	Human Neuropeptide Y Y2 Receptor fusion protein, ~{N}-[4-[4-[(1~{S})-2-(diethylamino)-2-oxidanylidene-1-phenyl-ethyl]piperazin-1-yl]-3-fluoranyl-phenyl]-2-pyridin-3-yl-benzamide, FLAVIN MONONUCLEOTIDE (3 entities in total)
Functional Keywords	neuropeptide y y2 receptor, membrane protein
Biological source	Enterobacteria phage RB59 More
Total number of polymer chains	1
Total formula weight	75307.32
Authors	Tang, T.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2020-10-30, release date: 2021-01-27, Last modification date: 2023-11-29)
Primary citation	Tang, T.,Hartig, C.,Chen, Q.,Zhao, W.,Kaiser, A.,Zhang, X.,Zhang, H.,Qu, H.,Yi, C.,Ma, L.,Han, S.,Zhao, Q.,Beck-Sickinger, A.G.,Wu, B. Structural basis for ligand recognition of the neuropeptide Y Y 2 receptor. Nat Commun, 12:737-737, 2021 Cited by PubMed: 33531491 DOI: 10.1038/s41467-021-21030-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation