Author results

4IB4
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CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT2B-BRIL IN COMPLEX WITH ERGOTAMINE
Descriptor:Chimera protein of human 5-hydroxytryptamine receptor 2B and E. Coli soluble cytochrome b562, Ergotamine, PALMITIC ACID, ...
Authors:Wacker, D., Wang, C., Katritch, V., Han, G.W., Huang, X., Vardy, E., McCorvy, J.D., Jiang, Y., Chu, M., Siu, F.Y., Liu, W., Xu, H.E., Cherezov, V., Roth, B.L., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2012-12-07
Release date:2013-03-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural features for functional selectivity at serotonin receptors.
Science, 340, 2013
4JN9
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CRYSTAL STRUCTURE OF THE DEPH
Descriptor:DepH, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
Authors:Li, J., Wang, C., Zhang, Z.M., Zhou, J.H., Cheng, E.
Deposit date:2013-03-14
Release date:2014-04-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
4JNA
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CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228
Descriptor:DepH, Dimethyl FK228, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Li, J., Wang, C., Zhang, Z.M., Zhou, J.H., Cheng, E.
Deposit date:2013-03-14
Release date:2014-03-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
4KEG
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CRYSTAL STRUCTURE OF MBP FUSED HUMAN SPLUNC1
Descriptor:Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, B-OCTYLGLUCOSIDE, MAGNESIUM ION
Authors:Ning, F., Wang, C., Niu, L., Chu, H.W., Zhang, G.
Deposit date:2013-04-25
Release date:2014-04-30
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Lipid Ligands of the SPLUNC1 Protein
To be Published
4L15
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CRYSTAL STRUCTURE OF FIGL-1 AAA DOMAIN
Descriptor:Fidgetin-like protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE
Authors:Peng, W., Lin, Z., Li, W., Lu, J., Shen, Y., Wang, C.
Deposit date:2013-06-02
Release date:2013-09-04
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
4L16
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CRYSTAL STRUCTURE OF FIGL-1 AAA DOMAIN IN COMPLEX WITH ADP
Descriptor:Fidgetin-like protein 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Peng, W., Lin, Z., Li, W., Lu, J., Shen, Y., Wang, C.
Deposit date:2013-06-02
Release date:2013-09-04
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
4N40
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CRYSTAL STRUCTURE OF HUMAN EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 PROTEIN
Descriptor:Protein ECT2
Authors:Zou, Y., Shao, Z.H., Li, F.D., Gong, D., Wang, C., Gong, Q., Shi, Y.
Deposit date:2013-10-08
Release date:2014-08-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4
Febs Lett., 588, 2014
4N4X
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CRYSTAL STRUCTURE OF THE MBP FUSED HUMAN SPLUNC1 (NATIVE FORM)
Descriptor:Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION
Authors:Ning, F., Wang, C., Niu, L., Chu, H.W., Zhang, G.
Deposit date:2013-10-08
Release date:2014-09-17
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Lipid ligands of human SPLUNC1
To be Published
4O8H
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0.85A RESOLUTION STRUCTURE OF PEG 400 BOUND CYCLOPHILIN D
Descriptor:Peptidyl-prolyl cis-trans isomerase F, mitochondrial, DI(HYDROXYETHYL)ETHER, ...
Authors:Lovell, S., Valasani, K.R., Battaile, K.P., Wang, C., Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4O8I
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1.45A RESOLUTION STRUCTURE OF PEG 400 BOUND CYCLOPHILIN D
Descriptor:Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PENTAETHYLENE GLYCOL
Authors:Lovell, S., Valasani, K.R., Battaile, K.P., Wang, C., Yan, S.S.
Deposit date:2013-12-27
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4OR2
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HUMAN CLASS C G PROTEIN-COUPLED METABOTROPIC GLUTAMATE RECEPTOR 1 IN COMPLEX WITH A NEGATIVE ALLOSTERIC MODULATOR
Descriptor:Soluble cytochrome b562, Metabotropic glutamate receptor 1, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, ...
Authors:Wu, H., Wang, C., Gregory, K.J., Han, G.W., Cho, H.P., Xia, Y., Niswender, C.M., Katritch, V., Cherezov, V., Conn, P.J., Stevens, R.C., GPCR Network (GPCR)
Deposit date:2014-02-10
Release date:2014-03-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
4RDX
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STRUCTURE OF HISTIDINYL-TRNA SYNTHETASE IN COMPLEX WITH TRNA(HIS)
Descriptor:Histidine--tRNA ligase, tRNA(his), ADENOSINE MONOPHOSPHATE, ...
Authors:Xie, W., Tian, Q., Wang, C.
Deposit date:2014-09-20
Release date:2015-03-25
Last modified:2017-05-17
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
Nucleic Acids Res., 43, 2015
5DDZ
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CRYSTAL STRUCTURE OF THE RTA-C10-P2 COMPLEX
Descriptor:Ricin, 60S acidic ribosomal protein P2
Authors:Zhu, Y., Fan, X., Wang, C., Niu, L., Li, X., Teng, M.
Deposit date:2015-08-25
Release date:2016-09-07
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin
Sci Rep, 6, 2016
5GMV
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LC3B-FUNDC1 COMPLEX
Descriptor:Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1
Authors:Lv, M., Wang, C., Li, F.
Deposit date:2016-07-17
Release date:2017-03-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
Protein Cell, 8, 2017
5WTA
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CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS SDRE APO FORM
Descriptor:Serine-aspartate repeat-containing protein E
Authors:Wu, M., Zhang, Y., Hang, T., Wang, C., Yang, Y., Zang, J., Zhang, M., Zhang, X.
Deposit date:2016-12-10
Release date:2017-07-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
5WTB
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COMPLEX STRUCTURE OF STAPHYLOCOCCUS AUREUS SDRE WITH HUMAN COMPLEMENT FACTOR H
Descriptor:Serine-aspartate repeat-containing protein E, Peptide from Complement factor H
Authors:Wu, M., Zhang, Y., Hang, T., Wang, C., Yang, Y., Zang, J., Zhang, M., Zhang, X.
Deposit date:2016-12-10
Release date:2017-07-19
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
5WWW
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CRYSTAL STRUCTURE OF THE KH1 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(*GP*UP*UP*UP*AP*G)-3')
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWX
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CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), NICKEL (II) ION
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5WWZ
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CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C
Descriptor:RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION
Authors:Yang, L., Wang, C., Li, F., Gong, Q.
Deposit date:2017-01-05
Release date:2017-08-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
5Y4D
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CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS IN COMPLEX WITH ANKR/ANKB CHIMERIC AUTOINHIBITION SEGMENT
Descriptor:Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION
Authors:Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4E
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CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R8-14 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-B
Descriptor:Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION
Authors:Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Method:X-RAY DIFFRACTION (2.341 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4F
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CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R13-24 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-C
Descriptor:Ankyrin-2, CALCIUM ION, ACETATE ION
Authors:Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
Deposit date:2017-08-03
Release date:2017-09-13
Method:X-RAY DIFFRACTION (1.953 Å)
Cite:Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5YCO
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COMPLEX STRUCTURE OF PCNA WITH UHRF2
Descriptor:Proliferating cell nuclear antigen, E3 ubiquitin-protein ligase UHRF2, GLYCEROL, ...
Authors:Wu, M., Chen, W., Hang, T., Wang, C., Zhang, X., Zang, J.
Deposit date:2017-09-07
Release date:2017-11-15
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
5Z1R
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CRYSTAL STRUCTURE ANALYSIS OF THE BRD4
Descriptor:Bromodomain-containing protein 4, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, 1,2-ETHANEDIOL, ...
Authors:Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
Deposit date:2017-12-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structure Analysis of the BRD4
To Be Published
5Z1S
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CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1)
Descriptor:Bromodomain-containing protein 4, 5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide, NITRATE ION, ...
Authors:Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
Deposit date:2017-12-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal Structure Analysis of the BRD4(1)
To Be Published