4IB4 | | CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF 5-HT2B-BRIL IN COMPLEX WITH ERGOTAMINE | | Descriptor: | Chimera protein of human 5-hydroxytryptamine receptor 2B and E. Coli soluble cytochrome b562, Ergotamine, PALMITIC ACID, ... | | Authors: | Wacker, D., Wang, C., Katritch, V., Han, G.W., Huang, X., Vardy, E., McCorvy, J.D., Jiang, Y., Chu, M., Siu, F.Y., Liu, W., Xu, H.E., Cherezov, V., Roth, B.L., Stevens, R.C., GPCR Network (GPCR) | | Deposit date: | 2012-12-07 | | Release date: | 2013-03-13 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural features for functional selectivity at serotonin receptors.
Science, 340, 2013
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4JN9 | | CRYSTAL STRUCTURE OF THE DEPH | | Descriptor: | DepH, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ... | | Authors: | Li, J., Wang, C., Zhang, Z.M., Zhou, J.H., Cheng, E. | | Deposit date: | 2013-03-14 | | Release date: | 2014-04-09 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
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4JNA | | CRYSTAL STRUCTURE OF THE DEPH COMPLEX WITH DIMETHYL-FK228 | | Descriptor: | DepH, Dimethyl FK228, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Li, J., Wang, C., Zhang, Z.M., Zhou, J.H., Cheng, E. | | Deposit date: | 2013-03-14 | | Release date: | 2014-03-05 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
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4KEG | | CRYSTAL STRUCTURE OF MBP FUSED HUMAN SPLUNC1 | | Descriptor: | Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, B-OCTYLGLUCOSIDE, MAGNESIUM ION | | Authors: | Ning, F., Wang, C., Niu, L., Chu, H.W., Zhang, G. | | Deposit date: | 2013-04-25 | | Release date: | 2014-04-30 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The Lipid Ligands of the SPLUNC1 Protein
To be Published
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4L15 | | CRYSTAL STRUCTURE OF FIGL-1 AAA DOMAIN | | Descriptor: | Fidgetin-like protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE | | Authors: | Peng, W., Lin, Z., Li, W., Lu, J., Shen, Y., Wang, C. | | Deposit date: | 2013-06-02 | | Release date: | 2013-09-04 | | Last modified: | 2015-02-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
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4L16 | | CRYSTAL STRUCTURE OF FIGL-1 AAA DOMAIN IN COMPLEX WITH ADP | | Descriptor: | Fidgetin-like protein 1, ADENOSINE-5'-DIPHOSPHATE | | Authors: | Peng, W., Lin, Z., Li, W., Lu, J., Shen, Y., Wang, C. | | Deposit date: | 2013-06-02 | | Release date: | 2013-09-04 | | Last modified: | 2014-02-12 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the unusually strong ATPase activity of the AAA domain of the Caenorhabditis elegans fidgetin-like 1 (FIGL-1) protein.
J.Biol.Chem., 288, 2013
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4N40 | | CRYSTAL STRUCTURE OF HUMAN EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 PROTEIN | | Descriptor: | Protein ECT2 | | Authors: | Zou, Y., Shao, Z.H., Li, F.D., Gong, D., Wang, C., Gong, Q., Shi, Y. | | Deposit date: | 2013-10-08 | | Release date: | 2014-08-27 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (3.106 Å) | | Cite: | Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4
Febs Lett., 588, 2014
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4N4X | | CRYSTAL STRUCTURE OF THE MBP FUSED HUMAN SPLUNC1 (NATIVE FORM) | | Descriptor: | Maltose-binding periplasmic/Palate lung and nasal epithelium clone fusion protein, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION | | Authors: | Ning, F., Wang, C., Niu, L., Chu, H.W., Zhang, G. | | Deposit date: | 2013-10-08 | | Release date: | 2014-09-17 | | Last modified: | 2017-08-02 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Lipid ligands of human SPLUNC1
To be Published
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4O8H | | 0.85A RESOLUTION STRUCTURE OF PEG 400 BOUND CYCLOPHILIN D | | Descriptor: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Lovell, S., Valasani, K.R., Battaile, K.P., Wang, C., Yan, S.S. | | Deposit date: | 2013-12-27 | | Release date: | 2014-06-11 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (0.85 Å) | | Cite: | High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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4O8I | | 1.45A RESOLUTION STRUCTURE OF PEG 400 BOUND CYCLOPHILIN D | | Descriptor: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PENTAETHYLENE GLYCOL | | Authors: | Lovell, S., Valasani, K.R., Battaile, K.P., Wang, C., Yan, S.S. | | Deposit date: | 2013-12-27 | | Release date: | 2014-06-11 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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4OR2 | | HUMAN CLASS C G PROTEIN-COUPLED METABOTROPIC GLUTAMATE RECEPTOR 1 IN COMPLEX WITH A NEGATIVE ALLOSTERIC MODULATOR | | Descriptor: | Soluble cytochrome b562, Metabotropic glutamate receptor 1, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, ... | | Authors: | Wu, H., Wang, C., Gregory, K.J., Han, G.W., Cho, H.P., Xia, Y., Niswender, C.M., Katritch, V., Cherezov, V., Conn, P.J., Stevens, R.C., GPCR Network (GPCR) | | Deposit date: | 2014-02-10 | | Release date: | 2014-03-19 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
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4RDX | | STRUCTURE OF HISTIDINYL-TRNA SYNTHETASE IN COMPLEX WITH TRNA(HIS) | | Descriptor: | Histidine--tRNA ligase, tRNA(his), ADENOSINE MONOPHOSPHATE, ... | | Authors: | Xie, W., Tian, Q., Wang, C. | | Deposit date: | 2014-09-20 | | Release date: | 2015-03-25 | | Last modified: | 2017-05-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
Nucleic Acids Res., 43, 2015
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5DDZ | | CRYSTAL STRUCTURE OF THE RTA-C10-P2 COMPLEX | | Descriptor: | Ricin, 60S acidic ribosomal protein P2 | | Authors: | Zhu, Y., Fan, X., Wang, C., Niu, L., Li, X., Teng, M. | | Deposit date: | 2015-08-25 | | Release date: | 2016-09-07 | | Last modified: | 2016-12-28 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin
Sci Rep, 6, 2016
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5GMV | | LC3B-FUNDC1 COMPLEX | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FUN14 domain-containing protein 1 | | Authors: | Lv, M., Wang, C., Li, F. | | Deposit date: | 2016-07-17 | | Release date: | 2017-03-08 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
Protein Cell, 8, 2017
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5WTA | | CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS SDRE APO FORM | | Descriptor: | Serine-aspartate repeat-containing protein E | | Authors: | Wu, M., Zhang, Y., Hang, T., Wang, C., Yang, Y., Zang, J., Zhang, M., Zhang, X. | | Deposit date: | 2016-12-10 | | Release date: | 2017-07-19 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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5WTB | | COMPLEX STRUCTURE OF STAPHYLOCOCCUS AUREUS SDRE WITH HUMAN COMPLEMENT FACTOR H | | Descriptor: | Serine-aspartate repeat-containing protein E, Peptide from Complement factor H | | Authors: | Wu, M., Zhang, Y., Hang, T., Wang, C., Yang, Y., Zang, J., Zhang, M., Zhang, X. | | Deposit date: | 2016-12-10 | | Release date: | 2017-07-19 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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5WWW | | CRYSTAL STRUCTURE OF THE KH1 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA | | Descriptor: | RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(*GP*UP*UP*UP*AP*G)-3') | | Authors: | Yang, L., Wang, C., Li, F., Gong, Q. | | Deposit date: | 2017-01-05 | | Release date: | 2017-08-23 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.798 Å) | | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
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5WWX | | CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C COMPLEX WITH RNA | | Descriptor: | RNA-binding E3 ubiquitin-protein ligase MEX3C, RNA (5'-R(P*AP*GP*AP*GP*U)-3'), NICKEL (II) ION | | Authors: | Yang, L., Wang, C., Li, F., Gong, Q. | | Deposit date: | 2017-01-05 | | Release date: | 2017-08-23 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
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5WWZ | | CRYSTAL STRUCTURE OF THE KH2 DOMAIN OF HUMAN RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX-3C | | Descriptor: | RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION | | Authors: | Yang, L., Wang, C., Li, F., Gong, Q. | | Deposit date: | 2017-01-05 | | Release date: | 2017-08-23 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem., 292, 2017
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5Y4D | | CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS IN COMPLEX WITH ANKR/ANKB CHIMERIC AUTOINHIBITION SEGMENT | | Descriptor: | Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION | | Authors: | Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M. | | Deposit date: | 2017-08-03 | | Release date: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
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5Y4E | | CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R8-14 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-B | | Descriptor: | Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION | | Authors: | Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M. | | Deposit date: | 2017-08-03 | | Release date: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.341 Å) | | Cite: | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
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5Y4F | | CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R13-24 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-C | | Descriptor: | Ankyrin-2, CALCIUM ION, ACETATE ION | | Authors: | Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M. | | Deposit date: | 2017-08-03 | | Release date: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (1.953 Å) | | Cite: | Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
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5YCO | | COMPLEX STRUCTURE OF PCNA WITH UHRF2 | | Descriptor: | Proliferating cell nuclear antigen, E3 ubiquitin-protein ligase UHRF2, GLYCEROL, ... | | Authors: | Wu, M., Chen, W., Hang, T., Wang, C., Zhang, X., Zang, J. | | Deposit date: | 2017-09-07 | | Release date: | 2017-11-15 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | Structure insights into the molecular mechanism of the interaction between UHRF2 and PCNA.
Biochem. Biophys. Res. Commun., 494, 2017
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5Z1R | | CRYSTAL STRUCTURE ANALYSIS OF THE BRD4 | | Descriptor: | Bromodomain-containing protein 4, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, 1,2-ETHANEDIOL, ... | | Authors: | Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C. | | Deposit date: | 2017-12-28 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal Structure Analysis of the BRD4
To Be Published
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5Z1S | | CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1) | | Descriptor: | Bromodomain-containing protein 4, 5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide, NITRATE ION, ... | | Authors: | Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C. | | Deposit date: | 2017-12-28 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Crystal Structure Analysis of the BRD4(1)
To Be Published
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