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2ANR
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CRYSTAL STRUCTURE (II) OF NOVA-1 KH1/KH2 DOMAIN TANDEM WITH 25NT RNA HAIRPIN
分子名称:5'-R(*CP*(5BU)P*CP*GP*CP*GP*GP*AP*UP*CP*AP*GP*UP*CP*AP*CP*CP*CP*AP*AP*GP*CP*GP*AP*G)-3', neuro-oncological ventral antigen 1, POTASSIUM ION, ...
著者Malinina, L., Teplova, M., Musunuru, K., Teplov, A., Darnell, J.C., Burley, S.K., Darnell, R.B., Patel, D.J.
登録日2005-08-11
公開日2006-10-24
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.
Structure, 19, 2011
2I9Y
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SOLUTION STRUCTURE OF ARABIDOPSIS THALIANA PROTEIN AT1G70830, A MEMBER OF THE MAJOR LATEX PROTEIN FAMILY
分子名称:major latex protein-like protein 28 or MLP-like protein 28
著者Volkman, B.F., de la Cruz, N.B., Lytle, B.L., Peterson, F.C., Center for Eukaryotic Structural Genomics (CESG)
登録日2006-09-06
公開日2006-09-19
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structures of two Arabidopsis thaliana major latex proteins represent novel helix-grip folds.
Proteins, 76, 2009
3F3M
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SIX CRYSTAL STRUCTURES OF TWO PHOSPHOPANTETHEINE ADENYLYLTRANSFERASES REVEAL AN ALTERNATIVE LIGAND BINDING MODE AND AN ASSOCIATED STRUCTURAL CHANGE
分子名称:Phosphopantetheine adenylyltransferase, 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE
著者Lee, H.H., Yoon, H.J., Suh, S.W.
登録日2008-10-31
公開日2009-10-20
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode
Acta Crystallogr.,Sect.F, 65, 2009
3LPY
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CRYSTAL STRUCTURE OF THE RRM DOMAIN OF CYP33
分子名称:Peptidyl-prolyl cis-trans isomerase E, SULFATE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Wang, Z., Patel, D.J.
登録日2010-02-07
公開日2010-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3LQH
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CRYSTAL STRUCTURE OF MLL1 PHD3-BROMO IN THE FREE FORM
分子名称:Histone-lysine N-methyltransferase MLL, ZINC ION
著者Wang, Z., Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3LQI
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CRYSTAL STRUCTURE OF MLL1 PHD3-BROMO COMPLEXED WITH H3(1-9)K4ME2 PEPTIDE
分子名称:MLL1 PHD3-Bromo, Histone H3, ZINC ION
著者Wang, Z., Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3LQJ
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CRYSTAL STRUCTURE OF MLL1 PHD3-BROMO COMPLEXED WITH H3(1-9)K4ME3 PEPTIDE
分子名称:MLL1 PHD3-Bromo, Histone H3, ZINC ION
著者Wang, Z., Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
4A4D
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN DEAD-BOX RNA HELICASE DDX5 (P68)
分子名称:PROBABLE ATP-DEPENDENT RNA HELICASE DDX5
著者Dutta, S., Choi, Y.W., Kotaka, M., Fielding, B.C., Tan, Y.J.
登録日2011-10-11
公開日2012-08-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Variable N-Terminal Region of Ddx5 Contains Structural Elements and Auto-Inhibits its Interaction with Ns5B of Hepatitis C Virus.
Biochem.J., 446, 2012
4ICQ
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STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION AND REACTION MECHANISM OF BACTERIAL AMINOPEPTIDASE PEPS
分子名称:Aminopeptidase PepS, ZINC ION
著者Ta, M.H., Kim, K.K., Lee, S.
登録日2012-12-11
公開日2013-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
Acta Crystallogr.,Sect.D, 69, 2013
4ICR
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STRUCTURAL BASIS FOR SUBSTRATE RECOGNITION AND REACTION MECHANISM OF BACTERIAL AMINOPEPTIDASE PEPS
分子名称:Aminopeptidase PepS, ZINC ION, CACODYLATE ION
著者Lee, S., Kim, K.K., Ta, M.H.
登録日2012-12-11
公開日2013-10-23
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
Acta Crystallogr.,Sect.D, 69, 2013
4ICS
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CRYSTAL STRUCTURE OF PEPS FROM STREPTOCOCCUS PNEUMONIAE IN COMPLEX WITH A SUBSTRATE
分子名称:Aminopeptidase PepS, ZINC ION, TRYPTOPHAN, ...
著者Lee, S., Kim, K.K., Ta, M.H.
登録日2012-12-11
公開日2013-10-23
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
Acta Crystallogr.,Sect.D, 69, 2013
4K6J
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HUMAN COHESIN INHIBITOR WAPL
分子名称:Wings apart-like protein homolog, SULFATE ION, ACETATE ION
著者Tomchick, D.R., Yu, H., Ouyang, Z.
登録日2013-04-16
公開日2013-06-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.6205 Å)
主引用文献Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WNK
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CRYSTAL STRUCTURE OF BOVINE G PROTEIN COUPLED-RECEPTOR KINASE 5 IN COMPLEX WITH CCG215022
分子名称:G protein-coupled receptor kinase 5, (4S)-4-{4-fluoro-3-[(pyridin-2-ylmethyl)carbamoyl]phenyl}-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide, SULFATE ION
著者Homan, K.T., Tesmer, J.J.G.
登録日2014-10-13
公開日2015-06-10
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor.
J.Biol.Chem., 290, 2015
5GLG
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THE NOVEL FUNCTION OF OSM1 UNDER ANAEROBIC CONDITION IN THE ER WAS REVEALED BY CRYSTAL STRUCTURE OF OSM1, A SOLUBLE FUMARATE REDUCTASE IN YEAST
分子名称:Fumarate reductase 2, SUCCINIC ACID, FLAVIN-ADENINE DINUCLEOTIDE
著者Park, H.H., Choi, J.Y.
登録日2016-07-11
公開日2017-07-12
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
Nat Commun, 9, 2018
5WG3
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HUMAN GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND CCG258748
分子名称:Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Bouley, R., Tesmer, J.J.G.
登録日2017-07-13
公開日2017-12-27
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.896 Å)
主引用文献Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol. Pharmacol., 92, 2017
5WG4
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HUMAN GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND CCG257284
分子名称:Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Bouley, R., Tesmer, J.J.G.
登録日2017-07-13
公開日2017-12-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol. Pharmacol., 92, 2017
5WG5
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HUMAN GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND CCG224061
分子名称:Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Bouley, R., Tesmer, J.J.G.
登録日2017-07-13
公開日2017-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol. Pharmacol., 92, 2017
5ZOO
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CRYSTAL STRUCTURE OF HISTONE DEACETYLASE 4 (HDAC4) IN COMPLEX WITH A SMRT COREPRESSOR SP1 FRAGMENT
分子名称:Histone deacetylase 4, SMRT corepressor SP1 fragment, POTASSIUM ION, ...
著者Park, S.Y., Hwang, H.J., Kim, J.S.
登録日2018-04-13
公開日2018-11-14
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4.
Nucleic Acids Res., 46, 2018
5ZOP
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CRYSTAL STRUCTURE OF HISTONE DEACETYLASE 4 (HDAC4) IN COMPLEX WITH A SMRT COREPRESSOR SP2 FRAGMENT
分子名称:Histone deacetylase 4, SMRT corepressor SP2 fragment, POTASSIUM ION, ...
著者Park, S.Y., Hwang, H.J., Kim, J.S.
登録日2018-04-13
公開日2018-10-10
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Structural basis of the specific interaction of SMRT corepressor with histone deacetylase 4.
Nucleic Acids Res., 46, 2018
5ZYN
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FUMARATE REDUCTASE
分子名称:Fumarate reductase 2, SUCCINIC ACID, FLAVIN MONONUCLEOTIDE, ...
著者Park, H.H., Kim, C.M.
登録日2018-05-25
公開日2018-10-03
最終更新日2018-12-12
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
Nat Commun, 9, 2018
6JYN
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GII.13/21 NOROVIRUSES RECOGNIZE GLYCANS WITH A TERMINAL BETA-GALACTOSE VIA AN UNCONVENTIONAL GLYCAN BINDING SITE
分子名称:human norovirus P domain protein, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE
著者Duan, Z., Xin, C.
登録日2019-04-26
公開日2019-05-22
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6JYO
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GII.13/21 NOROVIRUSES RECOGNIZE GLYCANS WITH A TERMINAL BETA-GALACTOSE VIA AN UNCONVENTIONAL GLYCAN BINDING SITE
分子名称:norovirus P domain protein
著者Duan, Z., Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6JYR
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GII.13/21 NOROVIRUSES RECOGNIZE GLYCANS WITH A TERMINAL BETA-GALACTOSE VIA AN UNCONVENTIONAL GLYCAN BINDING SITE
分子名称:norovirus P domain protein, GLYCEROL
著者Duan, Z., Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
6JYS
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GII.13/21 NOROVIRUSES RECOGNIZE GLYCANS WITH A TERMINAL BETA-GALACTOSE VIA AN UNCONVENTIONAL GLYCAN BINDING SITE
分子名称:human norovirus P protein, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ...
著者Duan, Z., Xin, C.
登録日2019-04-27
公開日2019-05-22
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.697 Å)
主引用文献GII.13/21 Noroviruses Recognize Glycans with a Terminal beta-Galactose via an Unconventional Glycan Binding Site.
J.Virol., 93, 2019
2BF2
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CRYSTAL STRUCTURE OF NATIVE TOLUENE-4-MONOOXYGENASE CATALYTIC EFFECTOR PROTEIN, T4MOD
分子名称:TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D
著者Lountos, G.T., Mitchell, K.H., Studts, J.M., Fox, B.G., Orville, A.M.
登録日2004-12-03
公開日2005-05-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein
Biochemistry, 44, 2005