3JAI | | STRUCTURE OF A MAMMALIAN RIBOSOMAL TERMINATION COMPLEX WITH ABCE1, ERF1(AAQ), AND THE UGA STOP CODON | | Descriptor: | uL2, uL3, uL4, ... | | Authors: | Brown, A., Shao, S., Murray, J., Hegde, R.S., Ramakrishnan, V. | | Deposit date: | 2015-06-10 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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3JAM | | CRYOEM STRUCTURE OF 40S-EIF1A-EIF1 COMPLEX FROM YEAST | | Descriptor: | 18S rRNA, uS2, eS1, ... | | Authors: | Llacer, J.L., Hussain, T., Ramakrishnan, V. | | Deposit date: | 2015-06-17 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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3JAP | | STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION | | Descriptor: | Met-tRNAi (U31:A39 variant), 18S rRNA, mRNA, ... | | Authors: | Llacer, J.L., Hussain, T., Ramakrishnan, V. | | Deposit date: | 2015-06-18 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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3JAQ | | STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN CONFORMATION | | Descriptor: | Met-tRNAi, 18S rRNA, mRNA, ... | | Authors: | Llacer, J.L., Hussain, T., Ramakrishnan, V. | | Deposit date: | 2015-06-18 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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3OTO | | CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM A KSGA MUTANT OF THERMUS THERMOPHILUS (HB8) | | Descriptor: | 16S rRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Demirci, H., Murphy IV, F., Belardinelli, R., Kelley, A.C., Ramakrishnan, V., Gregory, S.T., Dahlberg, A.E., Jogl, G. | | Deposit date: | 2010-09-13 | | Release date: | 2010-09-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.69 Å) | | Cite: | Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
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487D | |
4AQY | | STRUCTURE OF RIBOSOME-APRAMYCIN COMPLEXES | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Matt, T., Ng, C.L., Lang, K., Sha, S.H., Akbergenov, R., Shcherbakov, D., Meyer, M., Duscha, S., Xie, J., Dubbaka, S.R., Perez-Fernandez, D., Vasella, A., Ramakrishnan, V., Schacht, J., Bottger, E.C. | | Deposit date: | 2012-04-20 | | Release date: | 2012-07-18 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4B3M | | CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 1 | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C. | | Deposit date: | 2012-07-25 | | Release date: | 2013-08-07 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
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4B3R | | CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 30 | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C. | | Deposit date: | 2012-07-26 | | Release date: | 2013-08-07 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
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4B3S | | CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 37 | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C. | | Deposit date: | 2012-07-26 | | Release date: | 2013-08-07 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
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4B3T | | CRYSTAL STRUCTURE OF THE 30S RIBOSOME IN COMPLEX WITH COMPOUND 39 | | Descriptor: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Ng, C.L., Lang, K., Shcherbakov, D., Matt, T., Perez-Fernandez, D., Patak, R., Meyer, M., Duscha, S., Akbergenov, R., Boukari, H., Freihofer, P., Kudyba, I., Reddy, M.S.K., Nandurikar, R.S., Ramakrishnan, V., Vasella, A., Bottger, E.C. | | Deposit date: | 2012-07-26 | | Release date: | 2013-08-07 | | Last modified: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics
Nat.Commun., 5, 2014
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4FXI | |
4JV5 | | CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V. | | Deposit date: | 2013-03-25 | | Release date: | 2013-06-26 | | Last modified: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (3.162 Å) | | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
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4JYA | | CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V. | | Deposit date: | 2013-03-29 | | Release date: | 2013-06-26 | | Last modified: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (3.098 Å) | | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
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4K0K | | CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A SERINE-ASL AND MRNA CONTAINING A STOP CODON | | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ... | | Authors: | Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V. | | Deposit date: | 2013-04-04 | | Release date: | 2013-06-26 | | Last modified: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
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4KHP | | STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH DE-6-MSA-PACTAMYCIN | | Descriptor: | 16S Ribosomal RNA, 30S Ribosomal protein S2, 30S Ribosomal protein S3, ... | | Authors: | Tourigny, D.S., Fernandez, I.S., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2013-05-01 | | Release date: | 2013-06-05 | | Last modified: | 2013-10-30 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit.
J.Mol.Biol., 425, 2013
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4V4R | | CRYSTAL STRUCTURE OF THE WHOLE RIBOSOMAL COMPLEX. | | Descriptor: | 16S ribosomal RNA, P-site tRNA (Phe), E-site tRNA (Phe), ... | | Authors: | Petry, S., Brodersen, D.E., Murphy IV, F.V., Dunham, C.M., Selmer, M., Tarry, M.J., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2005-09-30 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (5.9 Å) | | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
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4V4S | | CRYSTAL STRUCTURE OF THE WHOLE RIBOSOMAL COMPLEX. | | Descriptor: | 16S ribosomal RNA, P-site tRNA (Phe), E-site tRNA (Phe), ... | | Authors: | Petry, S., Brodersen, D.E., Murphy IV, F.V., Dunham, C.M., Selmer, M., Tarry, M.J., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2005-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (6.76 Å) | | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
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4V4T | | CRYSTAL STRUCTURE OF THE WHOLE RIBOSOMAL COMPLEX WITH A STOP CODON IN THE A-SITE. | | Descriptor: | 16S ribosomal RNA, P-site tRNA (Phe), E-site tRNA (Phe), ... | | Authors: | Petry, S., Brodersen, D.E., Murphy IV, F.V., Dunham, C.M., Selmer, M., Tarry, M.J., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2005-10-12 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (6.46 Å) | | Cite: | Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
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4V51 | | STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Selmer, M., Dunham, C.M., Murphy, F.V., Weixlbaumer, A., Petry, S., Weir, J.R., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2006-07-31 | | Release date: | 2014-07-09 | | Last modified: | 2019-01-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the 70S ribosome complexed with mRNA and tRNA.
Science, 313, 2006
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4V5A | | STRUCTURE OF THE RIBOSOME RECYCLING FACTOR BOUND TO THE THERMUS THERMOPHILUS 70S RIBOSOME WITH MRNA, ASL-PHE AND TRNA-FMET | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Weixlbaumer, A., Petry, S., Dunham, C.M., Selmer, M., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2007-06-28 | | Release date: | 2014-07-09 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal structure of the ribosome recycling factor bound to the ribosome.
Nat. Struct. Mol. Biol., 14, 2007
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4V5C | | STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, PAROMOMYCIN, ACYLATED A-SITE TRNA, DEACYLATED P-SITE TRNA, AND E-SITE TRNA. | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2009-03-24 | | Release date: | 2014-07-09 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Insights Into Substrate Stabilization from Snapshots of the Peptidyl Transferase Center of the Intact 70S Ribosome
Nat.Struct.Mol.Biol., 16, 2009
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4V5D | | STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, PAROMOMYCIN, ACYLATED A- AND P-SITE TRNAS, AND E-SITE TRNA. | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2009-03-24 | | Release date: | 2014-07-09 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat. Struct. Mol. Biol., 16, 2009
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4V5E | | INSIGHTS INTO TRANSLATIONAL TERMINATION FROM THE STRUCTURE OF RF2 BOUND TO THE RIBOSOME | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Weixlbaumer, A., Jin, H., Neubauer, C., Voorhees, R.M., Petry, S., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2009-04-30 | | Release date: | 2014-07-09 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome.
Science, 322, 2008
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4V5F | | THE STRUCTURE OF THE RIBOSOME WITH ELONGATION FACTOR G TRAPPED IN THE POST-TRANSLOCATIONAL STATE | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ... | | Authors: | Gao, Y.-G., Selmer, M., Dunham, C.M., Weixlbaumer, A., Kelley, A.C., Ramakrishnan, V. | | Deposit date: | 2009-09-01 | | Release date: | 2014-07-09 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science, 326, 2009
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