Author results

4WRA
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COMPLEX OF 70S RIBOSOME WITH TRNA-TYR AND MRNA WITH A-A MISMATCH IN THE FIRST POSITION IN THE A-SITE AND WITH ANTIBIOTIC PAROMOMYCIN.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-23
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRO
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH C-A MISMATCH IN THE SECOND POSITION IN THE A-SITE
Descriptor:16S ribosomal RNA, tRNA-Phe, tRNA-fMet, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-24
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WSD
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH C-A MISMATCH IN THE SECOND POSITION IN THE A-SITE AND WITH ANTIBIOTIC PAROMOMYCIN.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-27
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WSM
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COMPLEX OF 70S RIBOSOME WITH TRNA-LEU AND MRNA WITH G-U MISMATCH IN THE FIRST POSITION IN THE A- AND P-SITES
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-28
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WT1
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COMPLEX OF 70S RIBOSOME WITH TRNA-PHE AND MRNA WITH A-A MISMATCH IN THE SECOND POSITION IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-29
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WU1
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COMPLEX OF 70S RIBOSOME WITH TRNA-TYR AND MRNA WITH G-U MISMATCH IN THE SECOND POSITION IN THE P-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-10-30
Release date:2015-06-10
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WZD
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COMPLEX OF 70S RIBOSOME WITH COGNATE TRNA-TYR IN THE P-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-11-19
Release date:2015-06-10
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WZO
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COMPLEX OF 70S RIBOSOME WITH TRNA-FMET AND MRNA
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2014-11-20
Release date:2015-06-10
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
5DC3
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COMPLEX OF YEAST 80S RIBOSOME WITH NON-MODIFIED EIF5A
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-23
Release date:2016-06-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
5DGE
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COPING WITH PROLINE STALLING: STRUCTURAL BASIS OF HYPUSINE-INDUCED PROTEIN SYNTHESIS BY THE EUKARYOTIC RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-27
Release date:2017-01-25
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DGF
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-27
Release date:2016-12-14
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DGV
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
Descriptor:Saccharomyces cerevisiae S288c RDN37-1 miscRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-28
Release date:2016-12-14
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5E7K
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND COGNATE TRNALYS IN THE A-SITE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-10-12
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5E81
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH WOBBLE PAIR
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-10-13
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5EL4
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH A U-U MISMATCH IN THE FIRST POSITION
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5EL5
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH A U-U MISMATCH IN THE SECOND POSITION
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5EL6
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH A U-U MISMATCH IN THE FIRST POSITION AND ANTIBIOTIC PAROMOMYCIN
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5EL7
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA AND TRNALYS IN THE A-SITE WITH A U-U MISMATCH IN THE SECOND POSITION AND ANTIBIOTIC PAROMOMYCIN
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Khusainov, I., Yusupov, M., Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5FCI
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STRUCTURE OF THE VACANT UL3 W255C MUTANT 80S YEAST RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Mailliot, J., Garreau de Loubresse, N., Yusupova, G., Dinman, J.D., Yusupov, M.
Deposit date:2015-12-15
Release date:2016-05-11
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
5FCJ
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STRUCTURE OF THE ANISOMYCIN-CONTAINING UL3 W255C MUTANT 80S YEAST RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Mailliot, J., Garreau de Loubresse, N., Yusupova, G., Dinman, J.D., Yusupov, M.
Deposit date:2015-12-15
Release date:2016-05-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
5IB7
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET, NEAR-COGNATE TRNALYS WITH U-G MISMATCH IN THE A-SITE AND ANTIBIOTIC PAROMOMYCIN
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5IB8
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET AND NEAR-COGNATE TRNALYS WITH U-G MISMATCH IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5IBB
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STRUCTURE OF T. THERMOPHILUS 70S RIBOSOME COMPLEX WITH MRNA, TRNAFMET AND COGNATE TRNAVAL IN THE A-SITE
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Rozov, A., Demeshkina, N., Yusupov, M., Yusupova, G.
Deposit date:2016-02-22
Release date:2016-05-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix.
Nucleic Acids Res., 44, 2016
5LI0
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70S RIBOSOME FROM STAPHYLOCOCCUS AUREUS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Khusainov, I., Vicens, Q., Bochler, A., Grosse, F., Myasnikov, A., Menetret, J.F., Chicher, J., Marzi, S., Romby, P., Yusupova, G., Yusupov, M., Hashem, Y.
Deposit date:2016-07-13
Release date:2016-12-28
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the 70S ribosome from human pathogen Staphylococcus aureus.
Nucleic Acids Res., 44, 2016
5ND8
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HIBERNATING RIBOSOME FROM STAPHYLOCOCCUS AUREUS (UNROTATED STATE)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Khusainov, I., Vicens, Q., Ayupov, R., Usachev, K., Myasnikov, A., Simonetti, A., Validov, S., Kieffer, B., Yusupova, G., Yusupov, M., Hashem, Y.
Deposit date:2017-03-07
Release date:2017-06-28
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017