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2IQ6
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CRYSTAL STRUCTURE OF THE AMINOPEPTIDASE FROM VIBRIO PROTEOLYTICUS IN COMPLEXATION WITH LEUCYL-LEUCYL-LEUCINE.
Descriptor:Bacterial leucyl aminopeptidase, Peptide, (Leucyl-leucyl-leucine), ...
Authors:Kumar, A., Narayanan, B., Kim, J.-J.P., Bennett, B.
Deposit date:2006-10-13
Release date:2007-08-28
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Experimental evidence for a metallohydrolase mechanism in which the nucleophile is not delivered by a metal ion: EPR spectrokinetic and structural studies of aminopeptidase from Vibrio proteolyticus
Biochem.J., 403, 2007
2RKW
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INTERMEDIATE POSITION OF ATP ON ITS TRAIL TO THE BINDING POCKET INSIDE THE SUBUNIT B MUTANT R416W OF THE ENERGY CONVERTER A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase beta chain
Authors:Kumar, A., Manimekalai, M.S.S., Balakrishna, A.M., Hunke, C., Gruber, G.
Deposit date:2007-10-18
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase
Proteins, 75, 2009
3B2Q
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INTERMEDIATE POSITION OF ATP ON ITS TRAIL TO THE BINDING POCKET INSIDE THE SUBUNIT B MUTANT R416W OF THE ENERGY CONVERTER A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase beta chain, ADENOSINE-5'-TRIPHOSPHATE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ...
Authors:Kumar, A., Manimekalai, M.S.S., Balakrishna, A.M., Hunke, C., Gruber, G.
Deposit date:2007-10-19
Release date:2008-09-09
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase
Proteins, 75, 2009
3DSR
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ADP IN TRANSITION BINDING SITE IN THE SUBUNIT B OF THE ENERGY CONVERTER A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase beta chain, ADENOSINE-5'-DIPHOSPHATE
Authors:Kumar, A., Manimekalai, S.M.S., Balakrishna, A.M., Gruber, G.
Deposit date:2008-07-14
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the nucleotide-binding subunit B of the energy producer A1A0 ATP synthase in complex with adenosine diphosphate
Acta Crystallogr.,Sect.D, 64, 2008
3IKJ
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STRUCTURAL CHARACTERIZATION FOR THE NUCLEOTIDE BINDING ABILITY OF SUBUNIT A MUTANT S238A OF THE A1AO ATP SYNTHASE
Descriptor:V-type ATP synthase alpha chain, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Kumar, A., Manimekali, M.S.S., Balakrishna, A.M., Jeyakanthan, J., Gruber, G.
Deposit date:2009-08-06
Release date:2010-01-12
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution.
J.Mol.Biol., 396, 2010
3P9N
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RV2966C OF M. TUBERCULOSIS IS A RSMD-LIKE METHYLTRANSFERASE
Descriptor:POSSIBLE METHYLTRANSFERASE (METHYLASE), ACETATE ION
Authors:Kumar, A., Malhotra, K., Saigal, K., Sinha, K.M., Taneja, B.
Deposit date:2010-10-18
Release date:2011-04-06
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of Rv2966c protein reveals an RsmD-like methyltransferase from Mycobacterium tuberculosis and the role of its N-terminal domain in target recognition
J.Biol.Chem., 286, 2011
3SJ2
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A CRYSTAL STRUCTURE OF A MODEL OF THE REPEATING R(CGG) TRANSCRIPT FOUND IN FRAGILE X SYNDROME
Descriptor:RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'), ACETATE ION
Authors:Kumar, A., Pengfei, F., Park, H., Nettles, K., Guo, M., Disney, M.D.
Deposit date:2011-06-20
Release date:2011-08-03
Last modified:2011-09-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome.
Chembiochem, 12, 2011
3SYW
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CRYSTAL STRUCTURE OF THE TRIPLET REPEAT IN MYOTONIC DYSTROPHY REVEALS HETEROGENEOUS 1X1 NUCLEOTIDE UU INTERNAL LOOP CONFORMATIONS
Descriptor:RNA (5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3'), PHOSPHATE ION
Authors:Kumar, A., Park, H., Pengfei, F., Parkesh, R., Guo, M., Nettles, K.W., Disney, M.D.
Deposit date:2011-07-18
Release date:2012-04-25
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
3SZX
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CRYSTAL STRUCTURE OF THE TRIPLET REPEAT IN MYOTONIC DYSTROPHY REVEALS HETEROGENEOUS 1X1 NUCLEOTIDE UU INTERNAL LOOP CONFORMATIONS
Descriptor:RNA (5'-R(P*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3')
Authors:Kumar, A., Park, H., Pengfei, F., Parkesh, R., Guo, M., Nettles, K.W., Disney, M.D.
Deposit date:2011-07-19
Release date:2012-04-25
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations
Biochemistry, 50, 2011
4R60
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CRYSTAL STRUCTURE OF XAA-PRO DIPEPTIDASE FROM XANTHOMONAS CAMPESTRIS
Descriptor:Proline dipeptidase, PHOSPHATE ION, MANGANESE (II) ION, ...
Authors:Kumar, A., Ghosh, B., Are, V.N., Jamdar, S.N., Makde, R.D., Sharma, S.M.
Deposit date:2014-08-22
Release date:2014-09-17
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris
to be published
5C9L
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CRYSTAL STRUCTURE OF NATIVE PLL LECTIN FROM PHOTORHABDUS LUMINESCENS AT 1.65 A RESOLUTION
Descriptor:PLL lectin, MERCURY (II) ION, CALCIUM ION, ...
Authors:Kumar, A., Sykorova, P., Demo, G., Dobes, P., Hyrsl, P., Wimmerova, M.
Deposit date:2015-06-27
Release date:2016-10-19
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure.
J.Biol.Chem., 291, 2016
5C9O
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CRYSTAL STRUCTURE OF RECOMBINANT PLL LECTIN FROM PHOTORHABDUS LUMINESCENS AT 1.5 A RESOLUTION
Descriptor:PLL lectin, GLYCEROL
Authors:Kumar, A., Sykorova, P., Demo, G., Dobes, P., Hyrsl, P., Wimmerova, M.
Deposit date:2015-06-28
Release date:2016-10-19
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure.
J.Biol.Chem., 291, 2016
5C9P
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CRYSTAL STRUCTURE OF RECOMBINANT PLL LECTIN COMPLEXED WITH L-FUCOSE FROM PHOTORHABDUS LUMINESCENS AT 1.75 A RESOLUTION
Descriptor:PLL lectin, ALPHA-L-FUCOSE, GLYCEROL
Authors:Kumar, A., Sykorova, P., Demo, G., Dobes, P., Hyrsl, P., Wimmerova, M.
Deposit date:2015-06-28
Release date:2016-10-19
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A Novel Fucose-binding Lectin from Photorhabdus luminescens (PLL) with an Unusual Heptabladed beta-Propeller Tetrameric Structure.
J.Biol.Chem., 291, 2016
5CDE
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R372A MUTANT OF XAA-PRO DIPEPTIDASE FROM XANTHOMONAS CAMPESTRIS
Descriptor:Proline dipeptidase, SULFATE ION, ZINC ION
Authors:Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.
Deposit date:2015-07-03
Release date:2016-09-14
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:R372A mutant of Xaa-Pro dipeptidase from Xanthomonas campestris at 1.85 Angstrom resolution
To Be Published
5CDL
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PROLINE DIPEPTIDASE FROM DEINOCOCCUS RADIODURANS (SELENOMETHIONINE DERIVATIVE)
Descriptor:Proline dipeptidase, MANGANESE (II) ION, PHOSPHATE ION
Authors:Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.
Deposit date:2015-07-04
Release date:2016-08-10
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Proline dipeptidase from Deinococcus radiodurans (selenomethionine derivative)
To Be Published
5CDV
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PROLINE DIPEPTIDASE FROM DEINOCOCCUS RADIODURANS R1
Descriptor:Proline dipeptidase, MANGANESE (II) ION, SODIUM ION, ...
Authors:Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.
Deposit date:2015-07-05
Release date:2016-08-10
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Proline dipeptidase from Deinococcus radiodurans R1 at 1.45 Angstrom resolution
To Be Published
5CIK
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CRYSTAL STRUCTURE OF XAA-PRO DIPEPTIDASE FROM XANTHOMONAS CAMPESTRIS IN CITRATE CONDITION
Descriptor:Proline dipeptidase, CITRIC ACID, GLYCEROL
Authors:Kumar, A., Are, V., Ghosh, B., Agrawal, U., Jamdar, S., Makde, R.D.
Deposit date:2015-07-13
Release date:2016-07-20
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris in citrate condition
To Be Published
5DSS
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MP-4 CONTRIBUTES TO SNAKE VENOM NEUTRALIZATION BY MUCUNA PRURIENS SEEDS THROUGH STIMULATION OF CROSS-REACTIVE ANTIBODIES
Descriptor:MP-4
Authors:Kumar, A., Nair, D.T., Salunke, D.M.
Deposit date:2015-09-17
Release date:2016-03-30
Last modified:2016-04-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:MP-4 Contributes to Snake Venom Neutralization by Mucuna pruriens Seeds through an Indirect Antibody-mediated Mechanism.
J.Biol.Chem., 291, 2016
5ID2
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ASYMMETRY IN THE ACTIVE SITE OF MYCOBACTERIUM TUBERCULOSIS AHPE UPON EXPOSURE TO MYCOTHIOL
Descriptor:Putative peroxiredoxin Rv2238c, GLYCEROL, ACETATE ION
Authors:Kumar, A., Balakrishna, A.M., Gruber, G.
Deposit date:2016-02-23
Release date:2016-08-03
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol
Free Radic. Biol. Med., 97, 2016
5OAT
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PINK1 STRUCTURE
Descriptor:Serine/threonine-protein kinase PINK1, mitochondrial-like Protein, MAGNESIUM ION
Authors:Kumar, A., Tamjar, J., Woodroof, H.I., Raimi, O.G., Waddell, A.Y., Peggie, M., Muqit, M.M.K., van Aalten, D.M.F.
Deposit date:2017-06-23
Release date:2017-10-11
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Structure of PINK1 and mechanisms of Parkinson's disease associated mutations.
Elife, 6, 2017
5Y05
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STRUCTURAL CHARACTERIZATION OF MSMEG_4306 FROM MYCOBACTERIUM SMEGMATIS
Descriptor:msmeg_4306, ZINC ION
Authors:Kumar, A., Karthikeyan, S.
Deposit date:2017-07-14
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Crystal structure of the MSMEG_4306 gene product from Mycobacterium smegmatis
Acta Crystallogr F Struct Biol Commun, 74, 2018
5Y06
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STRUCTURAL CHARACTERIZATION OF MSMEG_4306 FROM MYCOBACTERIUM SMEGMATIS
Descriptor:msmeg_4306, GLYCEROL, ZINC ION
Authors:Kumar, A., Karthikeyan, S.
Deposit date:2017-07-14
Release date:2018-05-02
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Crystal structure of the MSMEG_4306 gene product from Mycobacterium smegmatis
Acta Crystallogr F Struct Biol Commun, 74, 2018
3IX0
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CRYSTAL STRUCTURE OF HUMAN SEMINAL PLASMA PROTEIN PSP94
Descriptor:Beta-microseminoprotein
Authors:Kumar, M., Kumar, A., Jagtap, D.D., Mahale, S.D.
Deposit date:2009-09-03
Release date:2010-03-16
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of prostate secretory protein PSP94 shows an edge-to-edge association of two monomers to form a homodimer
J.Mol.Biol., 397, 2010
5FCF
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CRYSTAL STRUCTURE OF XAA-PRO DIPEPTIDASE FROM XANTHOMONAS CAMPESTRIS, PHOSPHATE AND MN BOUND
Descriptor:Proline dipeptidase, GLY-GLY-GLY, MANGANESE (II) ION, ...
Authors:Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.D.
Deposit date:2015-12-15
Release date:2016-12-07
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
Biochim. Biophys. Acta, 1865, 2017
5FCH
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CRYSTAL STRUCTURE OF XAA-PRO DIPEPTIDASE FROM XANTHOMONAS CAMPESTRIS, PHOSPHATE AND ZN BOUND
Descriptor:Proline dipeptidase, GLY-GLY-GLY, ZINC ION, ...
Authors:Kumar, A., Are, V., Ghosh, B., Jamdar, S., Makde, R.D.
Deposit date:2015-12-15
Release date:2016-12-07
Last modified:2017-01-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
Biochim. Biophys. Acta, 1865, 2017