7CXA
Structure of human Galectin-3 CRD in complex with TD-139 belonging to P31 space group.
Summary for 7CXA
Entry DOI | 10.2210/pdb7cxa/pdb |
Related | 7CXB 7CXC 7CXD |
Descriptor | Galectin-3, CHLORIDE ION, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, ... (4 entities in total) |
Functional Keywords | beta-galactose binding protein, carbohydrate, sugar binding protein, td-139 |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 38498.50 |
Authors | Kumar, A. (deposition date: 2020-09-01, release date: 2021-09-01, Last modification date: 2023-11-29) |
Primary citation | Kumar, A.,Paul, M.,Panda, M.,Jayaram, S.,Kalidindi, N.,Sale, H.,Vetrichelvan, M.,Gupta, A.,Mathur, A.,Beno, B.,Regueiro-Ren, A.,Cheng, D.,Ramarao, M.,Ghosh, K. Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3. Glycobiology, 31:1390-1400, 2021 Cited by PubMed: 34228782DOI: 10.1093/glycob/cwab072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
Download full validation report