7CXA
Structure of human Galectin-3 CRD in complex with TD-139 belonging to P31 space group.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-3 | polymer | 165 | 18565.2 | 2 | UniProt (P17931) Pfam (PF00337) | Homo sapiens (Human) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,Galactoside-binding protein,GALBP,IgE-binding protein,L-31,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | C, E (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) PubChem (312) | |||
| 3 | D, F (A, B) | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside | non-polymer | 648.6 | 2 | Chemie (TD2) PubChem (73774610) PubChem (90109156) PubChem (118436792) PubChem (118679947) PubChem (118657353) PubChem (122418481) PubChem (126624445) PubChem (126624423) PubChem (130471368) PubChem (118404248) PubChem (118408645) PubChem (118507865) PubChem (134692124) PubChem (118680035) PubChem (126624426) PubChem (129261745) PubChem (140639477) PubChem (140820580) PubChem (145121529) PubChem (153447831) PubChem (173976503) PubChem (173733738) PubChem (173742413) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 108 - 250 (UniProt: P17931)
| PDB | External Database | Details |
|---|---|---|
| Met 86 | - | expression tag |
| Gly 87 | - | expression tag |
| Ser 88 | - | expression tag |
| Ser 89 | - | expression tag |
| His 90 | - | expression tag |
| His 91 | - | expression tag |
| His 92 | - | expression tag |
| His 93 | - | expression tag |
| His 94 | - | expression tag |
| His 95 | - | expression tag |
| Ser 96 | - | expression tag |
| Ser 97 | - | expression tag |
| Gly 98 | - | expression tag |
| Glu 99 | - | expression tag |
| Thr 100 | - | expression tag |
| Val 101 | - | expression tag |
| Arg 102 | - | expression tag |
| Phe 103 | - | expression tag |
| Gln 104 | - | expression tag |
| Gly 105 | - | expression tag |
| His 106 | - | expression tag |
| Met 107 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37130.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1368.2 | |
| All* | Total formula weight | 38498.5 |
