1A16
| AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU | Descriptor: | AMINOPEPTIDASE P, LEUCINE, MANGANESE (II) ION, ... | Authors: | Wilce, M.C, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | Deposit date: | 1997-12-22 | Release date: | 1999-04-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
1AV4
| |
1AVL
| |
1AVK
| CRYSTAL STRUCTURES OF THE COPPER-CONTAINING AMINE OXIDASE FROM ARTHROBACTER GLOBIFORMIS IN THE HOLO-AND APO-FORMS: IMPLICATIONS FOR THE BIOGENESIS OF TOPA QUINONE | Descriptor: | AMINE OXIDASE | Authors: | Wilce, M.C.J, Guss, J.M, Freeman, H.C, Tanizawa, K, Yamaguchi, H. | Deposit date: | 1997-09-16 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone. Biochemistry, 36, 1997
|
|
1JAW
| AMINOPEPTIDASE P FROM E. COLI LOW PH FORM | Descriptor: | ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION | Authors: | Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. | Deposit date: | 1997-12-22 | Release date: | 1999-04-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 95, 1998
|
|
1FS0
| |
1KSI
| CRYSTAL STRUCTURE OF A EUKARYOTIC (PEA SEEDLING) COPPER-CONTAINING AMINE OXIDASE AT 2.2A RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | Authors: | Wilce, M.C.J, Kumar, V, Freeman, H.C, Guss, J.M. | Deposit date: | 1996-07-20 | Release date: | 1997-12-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a eukaryotic (pea seedling) copper-containing amine oxidase at 2.2 A resolution. Structure, 4, 1996
|
|
1WVN
| |
8ENI
| Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor | Descriptor: | 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA | Authors: | Wilce, M.C.J, Cini, D.A. | Deposit date: | 2022-09-30 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus. ACS Infect Dis, 4, 2018
|
|
3RKY
| |
3RKX
| |
3RKW
| |
3RIR
| |
3KPQ
| Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope | Descriptor: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | Authors: | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | Deposit date: | 2009-11-16 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
|
|
4WWQ
| Apo structure of the Grb7 SH2 domain | Descriptor: | Growth factor receptor-bound protein 7, MALONIC ACID | Authors: | Watson, G.M, Ambaye, N.D, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-11-12 | Release date: | 2015-09-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
|
|
4X6S
| Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide | Descriptor: | Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1 | Authors: | Watson, G.M, Panjikar, S, Wilce, M.C, Wilce, J.A. | Deposit date: | 2014-12-09 | Release date: | 2015-09-23 | Last modified: | 2015-10-28 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target. J.Med.Chem., 58, 2015
|
|
5ITH
| |
4WOP
| Nucleotide Triphosphate Promiscuity in Mycobacterium tuberculosis Dethiobiotin Synthetase | Descriptor: | ATP-dependent dethiobiotin synthetase BioD, CYTIDINE-5'-TRIPHOSPHATE, SULFATE ION | Authors: | Salaemae, W, Yap, M.Y, Wegener, K.L, Booker, G.W, Wilce, M.C.J, Polyak, S.W. | Deposit date: | 2014-10-16 | Release date: | 2015-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.393 Å) | Cite: | Nucleotide triphosphate promiscuity in Mycobacterium tuberculosis dethiobiotin synthetase. Tuberculosis (Edinb), 95, 2015
|
|
1QHQ
| AURACYANIN, A BLUE COPPER PROTEIN FROM THE GREEN THERMOPHILIC PHOTOSYNTHETIC BACTERIUM CHLOROFLEXUS AURANTIACUS | Descriptor: | CHLORIDE ION, COPPER (II) ION, PROTEIN (AURACYANIN), ... | Authors: | Bond, C.S, Blankenship, R.E, Freeman, H.C, Guss, J.M, Maher, M, Selvaraj, F, Wilce, M.C.J, Willingham, K. | Deposit date: | 1999-05-25 | Release date: | 2001-03-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of auracyanin, a "blue" copper protein from the green thermophilic photosynthetic bacterium Chloroflexus aurantiacus. J.Mol.Biol., 306, 2001
|
|
1R0G
| mercury-substituted rubredoxin | Descriptor: | MERCURY (II) ION, Rubredoxin | Authors: | Maher, M, Cross, M, Wilce, M.C.J, Guss, J.M, Wedd, A.G. | Deposit date: | 2003-09-22 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Metal-substituted derivatives of the rubredoxin from Clostridium pasteurianum. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R0I
| cadmium-substituted rubredoxin | Descriptor: | CADMIUM ION, Rubredoxin | Authors: | Maher, M, Cross, M, Wilce, M.C.J, Guss, J.M, Wedd, A.G. | Deposit date: | 2003-09-22 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Metal-substituted derivatives of the rubredoxin from Clostridium pasteurianum. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R0J
| nickel-substituted rubredoxin | Descriptor: | NICKEL (II) ION, Rubredoxin | Authors: | Maher, M, Cross, M, Wilce, M.C.J, Guss, J.M, Wedd, A.G. | Deposit date: | 2003-09-22 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metal-substituted derivatives of the rubredoxin from Clostridium pasteurianum. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R0F
| Gallium-substituted rubredoxin | Descriptor: | GALLIUM (III) ION, Rubredoxin | Authors: | Maher, M, Cross, M, Wilce, M.C.J, Guss, J.M, Wedd, A.G. | Deposit date: | 2003-09-22 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Metal-substituted derivatives of the rubredoxin from Clostridium pasteurianum. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R0H
| cobalt-substituted rubredoxin | Descriptor: | COBALT (II) ION, Rubredoxin | Authors: | Maher, M, Cross, M, Wilce, M.C.J, Guss, J.M, Wedd, A.G. | Deposit date: | 2003-09-22 | Release date: | 2004-02-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Metal-substituted derivatives of the rubredoxin from Clostridium pasteurianum. Acta Crystallogr.,Sect.D, 60, 2004
|
|
5EEQ
| Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor | Descriptor: | Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION | Authors: | Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M. | Deposit date: | 2015-10-23 | Release date: | 2016-06-15 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7. Sci Rep, 6, 2016
|
|