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4XUK
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BU of 4xuk by Molmil
Crystal structure of hydrolase AbOPH in beta lactamase superfamily
Descriptor: Putative hydrolase, ZINC ION
Authors:Chen, J, Xu, J.H, Zhou, J.H.
Deposit date:2015-01-26
Release date:2015-10-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Marked enhancement of Acinetobacter sp. organophosphorus hydrolase activity by a single residue substitution Ile211Ala
Bioresour Bioprocess, 2015
6P1K
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BU of 6p1k by Molmil
Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-05-20
Release date:2020-02-26
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
1QU1
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BU of 1qu1 by Molmil
CRYSTAL STRUCTURE OF EHA2 (23-185)
Descriptor: PROTEIN (INFLUENZA RECOMBINANT HA2 CHAIN)
Authors:Chen, J, Skehel, J.J, Wiley, D.C.
Deposit date:1999-07-05
Release date:2000-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
Proc.Natl.Acad.Sci.USA, 96, 1999
2KMI
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BU of 2kmi by Molmil
MESD(12-155), The Core Structural Domain of MESD that Is Essential for Proper Folding of LRP5/6
Descriptor: Mesoderm development candidate 2
Authors:Chen, J, Wang, J.
Deposit date:2009-07-28
Release date:2010-06-23
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6.
J.Biomol.Nmr, 47, 2010
6IET
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BU of 6iet by Molmil
The crystal structure of TRIM66 PHD-Bromo domain
Descriptor: Tripartite motif-containing protein 66, ZINC ION
Authors:Chen, J.
Deposit date:2018-09-17
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells.
Nat Commun, 10, 2019
6IEU
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BU of 6ieu by Molmil
The structure of TRIM66 PHD-Bromo domain with unmodified H3 N terminal peptide
Descriptor: ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-LYS-SER-THR-GLY, GLYCEROL, Tripartite motif-containing protein 66, ...
Authors:Chen, J.
Deposit date:2018-09-17
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.787 Å)
Cite:TRIM66 reads unmodified H3R2K4 and H3K56ac to respond to DNA damage in embryonic stem cells.
Nat Commun, 10, 2019
6IF8
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BU of 6if8 by Molmil
Aeromonas hydrophila MtaN-2 complexed with adenine
Descriptor: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE
Authors:Chen, J, Liu, W, Wang, L, Shang, F, Lan, J, Chen, Y, Xu, Y.
Deposit date:2018-09-18
Release date:2018-10-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aeromonas hydrophila MtaN-2 complexed with adenine
To Be Published
4GY5
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BU of 4gy5 by Molmil
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
Descriptor: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
Authors:Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y.
Deposit date:2012-09-05
Release date:2012-11-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
6XEZ
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BU of 6xez by Molmil
Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Llewellyn, E.C, Campbell, E.A, Darst, S.A.
Deposit date:2020-06-14
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
Cell, 182, 2020
6PSU
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BU of 6psu by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSR
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BU of 6psr by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSW
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BU of 6psw by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSS
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BU of 6pss by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter
Descriptor: DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSQ
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BU of 6psq by Molmil
Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSV
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BU of 6psv by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
7RDX
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BU of 7rdx by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - open class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RDZ
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BU of 7rdz by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - apo class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE3
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BU of 7re3 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-11-24
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE1
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BU of 7re1 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC (composite)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE2
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BU of 7re2 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(1)-RTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RDY
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BU of 7rdy by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - engaged class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
7RE0
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BU of 7re0 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC - swiveled class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Helicase, ...
Authors:Chen, J, Malone, B, Campbell, E.A, Darst, S.A.
Deposit date:2021-07-12
Release date:2021-12-01
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex.
Nat.Struct.Mol.Biol., 29, 2022
6PST
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BU of 6pst by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter
Descriptor: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
Deposit date:2019-07-13
Release date:2020-03-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
1IHZ
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BU of 1ihz by Molmil
Structure of S. nuclease mutant quintuple mutant V23L/V66L/I72L/I92L/V99L
Descriptor: STAPHYLOCOCCAL NUCLEASE
Authors:Chen, J, Lu, Z, Sakon, J, Stites, W.E.
Deposit date:2001-04-20
Release date:2003-06-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Proteins with simplified hydrophobic cores compared to other packing mutants.
Biophys.Chem., 110, 2004
1II3
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BU of 1ii3 by Molmil
Structure of S. nuclease quintuple mutant V23I/V66L/I72L/I92L/V99L
Descriptor: STAPHYLOCOCCAL NUCLEASE
Authors:Chen, J, Lu, Z, Sakon, J, Stites, W.E.
Deposit date:2001-04-20
Release date:2003-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Proteins with simplified hydrophobic cores compared to other packing mutants.
Biophys.Chem., 110, 2004

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