7RE1
SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC (composite)
Summary for 7RE1
Entry DOI | 10.2210/pdb7re1/pdb |
EMDB information | 24430 |
Descriptor | RNA-directed RNA polymerase, CHAPSO, ALUMINUM FLUORIDE, ... (12 entities in total) |
Functional Keywords | rna-dependent rna polymerase, viral replication-transcription complex, transcription, viral proteins, replication-transcription complex, replication/transcription |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 8 |
Total formula weight | 327962.35 |
Authors | Chen, J.,Malone, B.,Campbell, E.A.,Darst, S.A. (deposition date: 2021-07-12, release date: 2021-12-01, Last modification date: 2024-06-05) |
Primary citation | Chen, J.,Wang, Q.,Malone, B.,Llewellyn, E.,Pechersky, Y.,Maruthi, K.,Eng, E.T.,Perry, J.K.,Campbell, E.A.,Shaw, D.E.,Darst, S.A. Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat.Struct.Mol.Biol., 29:250-260, 2022 Cited by PubMed: 35260847DOI: 10.1038/s41594-022-00734-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.91 Å) |
Structure validation
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