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4UWA
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BU of 4uwa by Molmil
Structure of the ryanodine receptor at resolution of 6.1 A in closed state
Descriptor: RYANODINE RECEPTOR 1
Authors:Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S.
Deposit date:2014-08-11
Release date:2014-12-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Architecture and Conformational Switch Mechanism of the Ryanodine Receptor.
Nature, 517, 2015
4UWE
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BU of 4uwe by Molmil
Structure of the ryanodine receptor at resolution of 8.5 A in partially open state
Descriptor: RYANODINE RECEPTOR 1
Authors:Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S.
Deposit date:2014-08-11
Release date:2014-12-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Architecture and Conformational Switch Mechanism of the Ryanodine Receptor.
Nature, 517, 2015
9FJM
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BU of 9fjm by Molmil
Cryo-EM structure of the phalloidin-bound pointed end of the actin filament.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S.
Deposit date:2024-05-31
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
Nat Commun, 2024
9FJO
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BU of 9fjo by Molmil
Structure of the undecorated pointed end of F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S.
Deposit date:2024-05-31
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
Nat Commun, 2024
9FJY
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BU of 9fjy by Molmil
Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S.
Deposit date:2024-05-31
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
Nat Commun, 2024
9FJU
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BU of 9fju by Molmil
Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S.
Deposit date:2024-05-31
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly
Nat Commun, 2024
5JLH
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BU of 5jlh by Molmil
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ...
Authors:von der Ecken, J, Heissler, S.M, Pathan-Chhatbar, S, Manstein, D.J, Raunser, S.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature, 534, 2016
8CQ2
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BU of 8cq2 by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, C16S, C20S, C870S, T1279C mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
8CPZ
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BU of 8cpz by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K1179W mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
8CQ0
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BU of 8cq0 by Molmil
Photorhabdus luminescens TcdA1 prepore-to-pore intermediate, K567W K2008W mutant
Descriptor: TcdA1
Authors:Nganga, P.N, Roderer, D, Belyy, A, Prumbaum, D, Raunser, S.
Deposit date:2023-03-03
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Kinetics of the syringe-like injection mechanism of Tc toxins
to be published
2OF5
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BU of 2of5 by Molmil
Oligomeric Death Domain complex
Descriptor: Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein
Authors:Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H.
Deposit date:2007-01-02
Release date:2007-04-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell(Cambridge,Mass.), 128, 2007
5JLF
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BU of 5jlf by Molmil
Structure of the F-actin-tropomyosin complex (Reprocessed)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:von der Ecken, J, Raunser, S.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2020-02-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.
Nature, 534, 2016
3J8A
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BU of 3j8a by Molmil
Structure of the F-actin-tropomyosin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:von der Ecken, J, Mueller, M, Lehman, W, Manstein, J.M, Penczek, A.P, Raunser, S.
Deposit date:2014-10-08
Release date:2014-12-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the F-actin--tropomyosin complex.
Nature, 519, 2015
7AHN
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BU of 7ahn by Molmil
Cryo-EM structure of F-actin stabilized by cis-optoJASP-8
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pospich, S, Raunser, S.
Deposit date:2020-09-24
Release date:2021-01-27
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
7AHQ
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BU of 7ahq by Molmil
Cryo-EM structure of F-actin stabilized by trans-optoJASP-8
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Pospich, S, Raunser, S.
Deposit date:2020-09-25
Release date:2021-01-27
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
8RTT
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BU of 8rtt by Molmil
Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P.
Deposit date:2024-01-29
Release date:2024-04-10
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
7Z7H
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BU of 7z7h by Molmil
Structure of P. luminescens TccC3-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, Actin, ...
Authors:Belyy, A, Raunser, S.
Deposit date:2022-03-15
Release date:2022-06-29
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Nat Commun, 13, 2022
7Z7I
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BU of 7z7i by Molmil
Structure of ADP-ribosylated F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, Actin, ...
Authors:Belyy, A, Raunser, S.
Deposit date:2022-03-15
Release date:2022-06-29
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.
Nat Commun, 13, 2022
7B16
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BU of 7b16 by Molmil
TRPC4 in complex with inhibitor GFB-9289
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, 5-chloranyl-4-(4-cyclohexyl-3-oxidanylidene-piperazin-1-yl)-1~{H}-pyridazin-6-one, CALCIUM ION, ...
Authors:Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
Deposit date:2020-11-23
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
7B0S
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BU of 7b0s by Molmil
TRPC4 in complex with inhibitor GFB-8438
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 5-chloranyl-4-[3-oxidanylidene-4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]-1~{H}-pyridazin-6-one, CALCIUM ION, ...
Authors:Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
Deposit date:2020-11-21
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
7B0J
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BU of 7b0j by Molmil
TRPC4 in LMNG detergent
Descriptor: 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CALCIUM ION, Transient receptor potential cation channel subfamily c member 4a
Authors:Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
Deposit date:2020-11-20
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
7B1G
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BU of 7b1g by Molmil
TRPC4 in complex with Calmodulin
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, CALCIUM ION, Calmodulin-1, ...
Authors:Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
Deposit date:2020-11-24
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
7B05
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BU of 7b05 by Molmil
TRPC4 in complex with inhibitor GFB-8749
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4-[4-[[4,4-bis(fluoranyl)cyclohexyl]methyl]-3-oxidanylidene-piperazin-1-yl]-5-chloranyl-1~{H}-pyridazin-6-one, CALCIUM ION, ...
Authors:Vinayagam, D, Quentin, D, Sistel, O, Merino, F, Stabrin, M, Hofnagel, O, Ledeboer, M.W, Malojcic, G, Raunser, S.
Deposit date:2020-11-18
Release date:2020-12-09
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of TRPC4 regulation by calmodulin and pharmacological agents.
Elife, 9, 2020
8RTY
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BU of 8rty by Molmil
Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P.
Deposit date:2024-01-29
Release date:2024-04-10
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (6.25 Å)
Cite:Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
7NJ0
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BU of 7nj0 by Molmil
CryoEM structure of the human Separase-Cdk1-cyclin B1-Cks1 complex
Descriptor: Cyclin-dependent kinase 1, Cyclin-dependent kinases regulatory subunit 1, G2/mitotic-specific cyclin-B1,G2/mitotic-specific cyclin-B1, ...
Authors:Yu, J, Raia, P, Ghent, C.M, Raisch, T, Sadian, Y, Barford, D, Raunser, S, Morgan, D.O, Boland, A.
Deposit date:2021-02-14
Release date:2021-08-04
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Nature, 596, 2021

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PDB entries from 2024-09-18

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