Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1TUB
DownloadVisualize
BU of 1tub by Molmil
TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, TAXOTERE, ...
Authors:Nogales, E, Downing, K.H.
Deposit date:1997-09-23
Release date:1998-10-07
Last modified:2024-06-05
Method:ELECTRON CRYSTALLOGRAPHY (3.7 Å)
Cite:Structure of the alpha beta tubulin dimer by electron crystallography.
Nature, 391, 1998
6CVJ
DownloadVisualize
BU of 6cvj by Molmil
Model of synthetic tau (four tandem repeats of first repeat sequence) bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nogales, E, Kellogg, E.H.
Deposit date:2018-03-28
Release date:2018-05-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
6CVN
DownloadVisualize
BU of 6cvn by Molmil
Model of synthetic tau (R2x4) bound to the microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nogales, E, Kellogg, E.H.
Deposit date:2018-03-28
Release date:2018-05-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Near-atomic model of microtubule-tau interactions.
Science, 360, 2018
6P5A
DownloadVisualize
BU of 6p5a by Molmil
Drosophila P element transposase strand transfer complex
Descriptor: DNA (44-MER), DNA (5'-D(P*AP*GP*GP*TP*GP*GP*TP*CP*CP*CP*GP*TP*CP*GP*G)-3'), DNA (5'-D(P*CP*GP*AP*AP*CP*TP*AP*TP*A)-3'), ...
Authors:Kellogg, E.H, Nogales, E, Ghanim, G, Rio, D.C.
Deposit date:2019-05-30
Release date:2019-10-30
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.
Nat.Struct.Mol.Biol., 26, 2019
1JFF
DownloadVisualize
BU of 1jff by Molmil
Refined structure of alpha-beta tubulin from zinc-induced sheets stabilized with taxol
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lowe, J, Li, H, Downing, K.H, Nogales, E.
Deposit date:2001-06-20
Release date:2001-09-19
Last modified:2023-08-16
Method:ELECTRON CRYSTALLOGRAPHY (3.5 Å)
Cite:Refined structure of alpha beta-tubulin at 3.5 A resolution.
J.Mol.Biol., 313, 2001
9C57
DownloadVisualize
BU of 9c57 by Molmil
Reconstituted P400 Subcomplex of the human TIP60 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-05
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C62
DownloadVisualize
BU of 9c62 by Molmil
P400 subcomplex of the native human TIP60 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-07
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (5.28 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
7B5O
DownloadVisualize
BU of 7b5o by Molmil
Cryo-EM structure of the human CAK bound to ICEC0942 at 2.5 Angstroms resolution
Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
Authors:Greber, B.J, Remis, J, Ali, S, Nogales, E.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
Biophys.J., 120, 2021
7B5Q
DownloadVisualize
BU of 7b5q by Molmil
Cryo-EM structure of the human CAK bound to ICEC0942 (PHENIX-OPLS3e)
Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
Authors:Greber, B.J, Remis, J, Ali, S, Nogales, E.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
Biophys.J., 120, 2021
9CC8
DownloadVisualize
BU of 9cc8 by Molmil
Hexameric state of the NRC4 resistosome
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, NLR-required for cell death 4
Authors:Liu, F, Yang, Z, Nogales, E, Staskawicz, B.J.
Deposit date:2024-06-21
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Activation of the helper NRC4 immune receptor forms a hexameric resistosome.
Cell, 187, 2024
9CC9
DownloadVisualize
BU of 9cc9 by Molmil
Dodecameric state of the NRC4 resistosome
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, NLR-required for cell death 4
Authors:Liu, F, Yang, Z, Nogales, E, Staskawicz, B.J.
Deposit date:2024-06-21
Release date:2024-09-11
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Activation of the helper NRC4 immune receptor forms a hexameric resistosome.
Cell, 187, 2024
6B5B
DownloadVisualize
BU of 6b5b by Molmil
Cryo-EM structure of the NAIP5-NLRC4-flagellin inflammasome
Descriptor: Baculoviral IAP repeat-containing protein 1e, Flagellin, NLR family CARD domain-containing protein 4
Authors:Tenthorey, J.L, Haloupek, N, Lopez-Blanco, J.R, Grob, P, Adamson, E, Hartenian, E, Lind, N.A, Bourgeois, N.M, Chacon, P, Nogales, E, Vance, R.E.
Deposit date:2017-09-29
Release date:2017-11-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Science, 358, 2017
4CMQ
DownloadVisualize
BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
Authors:Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
Deposit date:2014-01-17
Release date:2014-02-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
4CMP
DownloadVisualize
BU of 4cmp by Molmil
Crystal structure of S. pyogenes Cas9
Descriptor: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION
Authors:Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
Deposit date:2014-01-16
Release date:2014-02-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
6PE2
DownloadVisualize
BU of 6pe2 by Molmil
Drosophila P element transposase strand transfer complex
Descriptor: DNA (27-MER), DNA (5'-D(P*CP*GP*AP*AP*CP*TP*AP*TP*A)-3'), DNA (56-MER), ...
Authors:Kellogg, E.H, Nogales, E, Ghanim, G, Rio, D.C.
Deposit date:2019-06-19
Release date:2019-10-30
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts.
Nat.Struct.Mol.Biol., 26, 2019
9C47
DownloadVisualize
BU of 9c47 by Molmil
TRRAP module of the human TIP60 complex
Descriptor: E1A-binding protein p400, Transformation/transcription domain-associated protein
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-03
Release date:2024-08-14
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C4B
DownloadVisualize
BU of 9c4b by Molmil
Second BAF53a of the human TIP60 complex
Descriptor: Actin-like protein 6A
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-03
Release date:2024-08-14
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
9C6N
DownloadVisualize
BU of 9c6n by Molmil
ARP module of the human TIP60 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E.
Deposit date:2024-06-07
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
4BK0
DownloadVisualize
BU of 4bk0 by Molmil
Crystal structure of the KIX domain of human RECQL5 (domain-swapped dimer)
Descriptor: ATP-DEPENDENT DNA HELICASE Q5, DI(HYDROXYETHYL)ETHER
Authors:Kassube, S.A, Jinek, M, Fang, J, Tsutakawa, S, Nogales, E.
Deposit date:2013-04-21
Release date:2013-06-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Mimicry in Transcription Regulation of Human RNA Polymerase II by the DNA Helicase Recql5
Nat.Struct.Mol.Biol., 20, 2013
8FIY
DownloadVisualize
BU of 8fiy by Molmil
Cryo-EM structure of E. coli RNA polymerase Elongation complex in the Transcription-Translation Complex (RNAP in an anti-swiveled conformation)
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C.
Deposit date:2022-12-17
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
Cell, 186, 2023
8FIX
DownloadVisualize
BU of 8fix by Molmil
Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex harboring a terminal mismatch
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C.
Deposit date:2022-12-17
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
Cell, 186, 2023
8FIZ
DownloadVisualize
BU of 8fiz by Molmil
Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex)
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C.
Deposit date:2022-12-18
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery.
Cell, 186, 2023
6BJC
DownloadVisualize
BU of 6bjc by Molmil
TPX2_mini decorated GMPCPP-microtubule
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2017-11-05
Release date:2017-11-22
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insight into TPX2-stimulated microtubule assembly.
Elife, 6, 2017
7SJ8
DownloadVisualize
BU of 7sj8 by Molmil
13pf wildtype microtubule from recombinant human tubulin decorated with kinesin
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:LaFrance, B.J, Greber, B.J, Zhang, R, McCollum, C, Nogales, E.
Deposit date:2021-10-16
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SJ9
DownloadVisualize
BU of 7sj9 by Molmil
13pf E254A microtubule from recombinant human tubulin decorated with EB3
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ...
Authors:LaFrance, B.J, Greber, B.J, Zhang, R, McCollum, C, Nogales, E.
Deposit date:2021-10-16
Release date:2022-01-19
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon