Author results

4LQ6
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CRYSTAL STRUCTURE OF RV3717 REVEALS A NOVEL AMIDASE FROM M. TUBERCULOSIS
分子名称:N-acetymuramyl-L-alanine amidase-related protein, ZINC ION, SULFATE ION, ...
著者Kumar, A., Kumar, S., Kumar, D., Mishra, A., Dewangan, R.P., Shrivastava, P., Ramachandran, S., Taneja, B.
登録日2013-07-17
公開日2013-12-04
最終更新日2014-01-15
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
3KJZ
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CRYSTAL STRUCTURE OF NATIVE PEPTIDYL-TRNA HYDROLASE FROM MYCOBACTERIUM SMEGMATIS
分子名称:Peptidyl-tRNA hydrolase
著者Kumar, A., Singh, N., Yadav, R., Prem Kumar, R., Sharma, S., Arora, A., Singh, T.P.
登録日2009-11-04
公開日2010-08-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Fully-Folded Native and Partially-Folded Intermediate States of Peptidyl-tRNA Hydrolase from Mycobacterium smegmatis
To be Published
4L69
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RV2372C OF MYCOBACTERIUM TUBERCULOSIS IS RSME LIKE METHYLTRANSFERSE
分子名称:Ribosomal RNA small subunit methyltransferase E
著者Kumar, A., Taneja, B.
登録日2013-06-12
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 70, 2014
1JYM
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CRYSTALS OF PEPTIDE DEFORMYLASE FROM PLASMODIUM FALCIPARUM WITH TEN SUBUNITS PER ASYMMETRIC UNIT REVEAL CRITICAL CHARACTERISTICS OF THE ACTIVE SITE FOR DRUG DESIGN
分子名称:Peptide Deformylase, COBALT (II) ION
著者Kumar, A., Nguyen, K.T., Srivathsan, S., Ornstein, B., Turley, S., Hirsh, I., Pei, D., Hol, W.G.J.
登録日2001-09-12
公開日2002-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.
Structure, 10, 2002
3P2J
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM MYCOBACTERIUM SMEGMATIS AT 2.2 A RESOLUTION
分子名称:Peptidyl-tRNA hydrolase
著者Kumar, A., Singh, A., Yadav, R., Sinha, M., Arora, A., Sharma, S., Singh, T.P.
登録日2010-10-02
公開日2010-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal Structure of peptidyl-tRNA hydrolase from Mycobacterium smegmatis at 2.2 A resolution
To be Published
4DHW
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CRYSTAL STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA WITH ADIPIC ACID AT 2.4 ANGSTROM RESOLUTION
分子名称:Peptidyl-tRNA hydrolase, hexanedioic acid
著者Kumar, A., Singh, A., Singh, N., Sinha, M., Sharma, S., Arora, A., Singh, T.P.
登録日2012-01-30
公開日2012-02-29
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Crystal structure of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with Adipic acid at 2.4 Angstrom resolution
To be Published
4DJJ
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CRYSTAL STRUCTURE OF THE COMPLEX OF PEPTIDYL-TRNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA WITH PIMELIC ACID AT 2.9 ANGSTROM RESOLUTION
分子名称:Peptidyl-tRNA hydrolase, PIMELIC ACID
著者Kumar, A., Singh, A., Singh, N., Sinha, M., Sharma, S., Arora, A., Singh, T.P.
登録日2012-02-02
公開日2012-03-07
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Crystal structure of the complex of Peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with Pimelic acid at 2.9 Angstrom resolution
To be Published
4ERX
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CRYSTAL STRUCTURE OF THE COMPLEX OF PEPTIDYL-TRNA HYDROLASE FROM PSEUDOMONAS AERUGINOSA WITH DIETHYLENE GLYCOL AT 2.5 ANGSTROM RESOLUTION
分子名称:Peptidyl-tRNA hydrolase, DI(HYDROXYETHYL)ETHER
著者Kumar, A., Singh, A., Singh, N., Sinha, M., Sharma, S., Arora, A., Singh, T.P.
登録日2012-04-21
公開日2012-05-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the complex of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with diethylene glycol at 2.5 Angstrom resolution
To be Published
2M5R
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SOLUTION STRUCTURE OF HOLO-ACYL CARRIER PROTEIN OF LEISHMANIA MAJOR
分子名称:Acyl carrier protein, 4'-PHOSPHOPANTETHEINE
著者Kumar, A., Surolia, A., Sundd, M.
登録日2013-03-07
公開日2014-09-17
実験手法SOLUTION NMR
主引用文献NMR structures of the apo- and holo- forms of the acyl carrier protein of Leishmania major
To be Published
2N6C
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SOLUTION STRUCTURE FOR QUERCETIN COMPLEXED WITH C-MYC G-QUADRUPLEX DNA
分子名称:DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'), 3,5,7,3',4'-PENTAHYDROXYFLAVONE
著者Kumar, A., Tawani, A.
登録日2015-08-18
公開日2016-09-14
実験手法SOLUTION NMR
主引用文献Solution structure for quercetin complexed with c-myc G-quadruplex DNA
To be Published
3KK0
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CRYSTAL STRUCTURE OF PARTIALLY FOLDED INTERMEDIATE STATE OF PEPTIDYL-TRNA HYDROLASE FROM MYCOBACTERIUM SMEGMATIS
分子名称:Peptidyl-tRNA hydrolase, ISOPROPYL ALCOHOL, 1,2-ETHANEDIOL, ...
著者Kumar, A., Singh, N., Yadav, R., Sharma, S., Arora, A., Singh, T.P.
登録日2009-11-04
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of Fully-Folded Native and Partially-Folded Intermediate States of Peptidyl-tRNA Hydrolase from Mycobacterium smegmatis
To be Published
5C1Z
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PARKIN (UBLR0RBR)
分子名称:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
著者kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C23
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PARKIN (S65DUBLR0RBR)
分子名称:E3 ubiquitin-protein ligase parkin, ZINC ION, GLYCEROL, ...
著者Kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5N2W
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WT-PARKIN AND PUB COMPLEX
分子名称:E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ...
著者Kumar, A., Chaugule, V.K., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5N38
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S65DPARKIN AND PUB COMPLEX
分子名称:E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, DI(HYDROXYETHYL)ETHER, ...
著者Kumar, A., Chaugule, V.K., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5N74
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MICROTUBULE END BINDING PROTEIN COMPLEX
分子名称:Uncharacterized protein, GLY-SER-THR-ARG-ARG-ARG-THR-ARG-LEU-ARG-PRO-PRO-THR-PRO-LEU-SER-GLN-LEU-LEU-SER-PRO
著者Kumar, A., Steinmetz, M.
登録日2017-02-18
公開日2017-06-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Short Linear Sequence Motif LxxPTPh Targets Diverse Proteins to Growing Microtubule Ends.
Structure, 25, 2017
6JMI
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CRYSTAL STRUCTURE OF M.TUBERCULOSIS RV0081
分子名称:Uncharacterized HTH-type transcriptional regulator Rv0081, SULFATE ION
著者Kumar, A., Phulera, S., Mande, C.S.
登録日2019-03-11
公開日2019-04-10
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.896 Å)
主引用文献Structural basis of hypoxic gene regulation by the Rv0081 transcription factor of Mycobacterium tuberculosis.
Febs Lett., 593, 2019
1CEH
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STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER
分子名称:PHOSPHOLIPASE A2, CALCIUM ION
著者Kumar, A., Sekharudu, C., Ramakrishnan, B., Dupureur, C.M., Zhu, H., Tsai, M.-D., Sundaralingam, M.
登録日1994-11-16
公開日1995-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water.
Protein Sci., 3, 1994
1HXI
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AN UNEXPECTED EXTENDED CONFORMATION FOR THE THIRD TPR MOTIF OF THE PEROXIN PEX5 FROM TRYPANOSOMA BRUCEI
分子名称:PEROXISOME TARGETING SIGNAL 1 RECEPTOR PEX5, MAGNESIUM ION
著者Kumar, A., Roach, C., Hirsh, I.S., Turley, S., deWalque, S., Michels, P.A.M., Hol, W.G.J.
登録日2001-01-15
公開日2001-03-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.
J.Mol.Biol., 307, 2001
1YWV
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CRYSTAL STRUCTURES OF PROTO-ONCOGENE KINASE PIM1: A TARGET OF ABERRANT SOMATIC HYPERMUTATIONS IN DIFFUSE LARGE CELL LYMPHOMA
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-18
公開日2005-04-26
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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CRYSTAL STRUCTURE OF KINASE PIM1 WITH P123M MUTATION
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXT
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMPPNP
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXU
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, ADENOSINE MONOPHOSPHATE
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXX
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
分子名称:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
著者Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005