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1EXT
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EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
分子名称: MAGNESIUM ION, SULFATE ION, TUMOR NECROSIS FACTOR RECEPTOR
著者Naismith, J.H, Sprang, S.R.
登録日1996-07-03
公開日1997-01-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Structure, 4, 1996
3U3Q
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BU of 3u3q by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3S
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BU of 3u3s by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3TJE
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Crystal structure of Fas receptor extracellular domain in complex with Fab E09
分子名称: 1,2-ETHANEDIOL, CADMIUM ION, CHLORIDE ION, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-24
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3U3P
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BU of 3u3p by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3V
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BU of 3u3v by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3THM
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BU of 3thm by Molmil
Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ...
著者Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G.
登録日2011-08-19
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
3U3T
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BU of 3u3t by Molmil
The S-SAD phased crystal structure of the ecto-domain of Death Receptor 6 (DR6)
分子名称: Tumor necrosis factor receptor superfamily member 21
著者Ru, H, Zhao, L.X, Ding, W, Jiao, L.Y, Shaw, N, Zhang, L.G, Hung, L.W, Matsugaki, N, Wakatsuki, S, Liu, Z.J.
登録日2011-10-06
公開日2012-05-02
最終更新日2012-07-11
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
5L36
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Crystal Structure of a human FasL mutant in complex with human DcR3
分子名称: SODIUM ION, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor receptor superfamily member 6B
著者Liu, W, Bonanno, J.B, Almo, S.C.
登録日2016-08-03
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
4RSU
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Crystal structure of the light and hvem complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Liu, W, Ramagoal, U.A, Himmel, D, Bonanno, J.B, Nathenson, S.G, Almo, S.C, Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-11-11
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.
J.Exp.Med., 218, 2021
1JMA
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BU of 1jma by Molmil
CRYSTAL STRUCTURE OF THE HERPES SIMPLEX VIRUS GLYCOPROTEIN D BOUND TO THE CELLULAR RECEPTOR HVEA/HVEM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN D, HERPESVIRUS ENTRY MEDIATOR, ...
著者Carfi, A, Willis, S.H, Whitbeck, J.C, Krummenacker, C, Cohen, G.H, Eisenberg, R.J, Wiley, D.C.
登録日2001-07-17
公開日2001-09-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Herpes simplex virus glycoprotein D bound to the human receptor HveA.
Mol.Cell, 8, 2001
7KP7
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BU of 7kp7 by Molmil
asymmetric mTNF-alpha hTNFR1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Tumor necrosis factor, ...
著者Arakaki, T.L, Fox III, D, Edwards, T.E, Foley, A, Ceska, T.
登録日2020-11-10
公開日2021-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.
Nat Commun, 12, 2021
4YN0
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BU of 4yn0 by Molmil
Crystal structure of APP E2 domain in complex with DR6 CRD domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Amyloid beta A4 protein, MAGNESIUM ION, ...
著者Xu, K, Nikolov, D.
登録日2015-03-08
公開日2015-04-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
Genes Dev., 29, 2015
8HLB
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BU of 8hlb by Molmil
Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
分子名称: TR109 heavy chain, TR109 light chain, TR92 heavy chain, ...
著者Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K.
登録日2022-11-29
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Commun Biol, 6, 2023
3IJ2
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BU of 3ij2 by Molmil
Ligand-receptor structure
分子名称: Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16)
著者Feng, D, Garcia, K.C.
登録日2009-08-03
公開日2010-01-12
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
J.Mol.Biol., 396, 2010
6A3V
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BU of 6a3v by Molmil
Complex structure of human 4-1BB and 4-1BBL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Li, Y, Zhang, C, Chai, Y, Qi, J, Tien, P, Gao, S, Gao, G.F.
登録日2018-06-17
公開日2018-10-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.391 Å)
主引用文献Limited Cross-Linking of 4-1BB by 4-1BB Ligand and the Agonist Monoclonal Antibody Utomilumab.
Cell Rep, 25, 2018
3ALQ
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BU of 3alq by Molmil
Crystal structure of TNF-TNFR2 complex
分子名称: COBALT (II) ION, Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B
著者Mukai, Y, Nakamura, T, Yamagata, Y, Tsutsumi, Y.
登録日2010-08-06
公開日2010-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Solution of the Structure of the TNF-TNFR2 Complex
Sci.Signal., 3, 2010
1TNR
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BU of 1tnr by Molmil
CRYSTAL STRUCTURE OF THE SOLUBLE HUMAN 55 KD TNF RECEPTOR-HUMAN TNF-BETA COMPLEX: IMPLICATIONS FOR TNF RECEPTOR ACTIVATION
分子名称: TUMOR NECROSIS FACTOR BETA, TUMOR NECROSIS FACTOR RECEPTOR P55
著者Banner, D.W.
登録日1994-05-09
公開日1994-07-31
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Cell(Cambridge,Mass.), 73, 1993
1SG1
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BU of 1sg1 by Molmil
Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75
分子名称: Beta-nerve growth factor, CHLORIDE ION, Tumor necrosis factor receptor superfamily member 16
著者He, X.L, Garcia, K.C.
登録日2004-02-22
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
Science, 304, 2004
5BNQ
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BU of 5bnq by Molmil
Crystal structure of hRANKL-mRANK complex
分子名称: CHLORIDE ION, PHOSPHATE ION, SODIUM ION, ...
著者Ren, J.
登録日2015-05-26
公開日2015-10-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis.
Sci Rep, 5, 2015
3K51
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BU of 3k51 by Molmil
Crystal Structure of DcR3-TL1A complex
分子名称: Decoy receptor 3, Tumor necrosis factor ligand superfamily member 15, secreted form
著者Zhan, C, Patskovsky, Y, Yan, Q, Li, Z, Ramagopal, U.A, Nathenson, S.G, Almo, S.C.
登録日2009-10-06
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Decoy Strategies: The Structure of TL1A:DcR3 Complex.
Structure, 19, 2011
3BUK
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BU of 3buk by Molmil
Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16
著者Jiang, T, Gong, Y, Cao, P, Yu, H.J.
登録日2008-01-02
公開日2008-07-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.
Nature, 454, 2008
5CIR
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BU of 5cir by Molmil
Crystal structure of death receptor 4 (DR4; TNFFRSF10A) bound to TRAIL (TNFSF10)
分子名称: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 10, Tumor necrosis factor receptor superfamily member 10A, ...
著者Sheriff, S.
登録日2015-07-13
公開日2017-01-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex.
Acta Crystallogr F Struct Biol Commun, 71, 2015
6CPR
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Crystal structure of 4-1BBL/4-1BB complex in C2 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Aruna, B, Zajonc, D.M.
登録日2018-03-14
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6CU0
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Crystal structure of 4-1BBL/4-1BB (C121S) complex in P21 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9
著者Aruna, B, Zajonc, D.M, Doukov, T.
登録日2018-03-23
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018

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