3IJ2

Ligand-receptor structure

Summary for 3IJ2

Entry DOI	10.2210/pdb3ij2/pdb
Descriptor	Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16) (2 entities in total)
Functional Keywords	receptor and ligand, cleavage on pair of basic residues, disulfide bond, glycoprotein, growth factor, phosphoprotein, secreted, hormone-protein binding complex, hormone/protein binding
Biological source	Mus musculus (mouse) More
Total number of polymer chains	4
Total formula weight	87865.41
Authors	Feng, D.,Garcia, K.C. (deposition date: 2009-08-03, release date: 2010-01-12, Last modification date: 2021-10-13)
Primary citation	Feng, D.,Kim, T.,Ozkan, E.,Light, M.,Torkin, R.,Teng, K.K.,Hempstead, B.L.,Garcia, K.C. Molecular and structural insight into proNGF engagement of p75NTR and sortilin. J.Mol.Biol., 396:967-984, 2010 Cited by PubMed: 20036257 DOI: 10.1016/j.jmb.2009.12.030 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.75 Å)

Structure validation