1SG1
Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75
Summary for 1SG1
Entry DOI | 10.2210/pdb1sg1/pdb |
Descriptor | Beta-nerve growth factor, Tumor necrosis factor receptor superfamily member 16, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | nerve growth factor, ngf, p75, neurotrophin, common neurotrophin receptor, growth factor receptor, receptor-ligand complex, hormone-growth factor-membrane protein complex, hormone/growth factor/membrane protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01138 Membrane; Single-pass type I membrane protein: P07174 |
Total number of polymer chains | 3 |
Total formula weight | 44324.29 |
Authors | He, X.L.,Garcia, K.C. (deposition date: 2004-02-22, release date: 2004-06-01, Last modification date: 2023-08-23) |
Primary citation | He, X.L.,Garcia, K.C. Structure of nerve growth factor complexed with the shared neurotrophin receptor p75 Science, 304:870-875, 2004 Cited by PubMed: 15131306DOI: 10.1126/science.1095190 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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