2JF9

ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH A TAMOXIFEN-SPECIFIC PEPTIDE ANTAGONIST

Summary for 2JF9

• Entry DOI: 10.2210/pdb2jf9/pdb
• Related: 1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2BJ4 2FAI 2JFA 3ERD 3ERT
• Descriptor: ESTROGEN RECEPTOR, AB5 PEPTIDE, 4-HYDROXYTAMOXIFEN, ... (7 entities in total)
• Functional Keywords: transcription factor, lipid-binding, transcription, transcription regulation, ligand-binding domain (lbd), receptor, zinc-finger, dna-binding, steroid-binding, nuclear receptor, peptide antagonist, metal-binding, nuclear protein, phosphorylation
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Isoform 1: Nucleus . Isoform 3: Nucleus. Nucleus: P03372
• Total number of polymer chains: 6
• Total formula weight: 92318.93

Authors

Heldring, N.,Pawson, T.,McDonnell, D.,Treuter, E.,Gustafsson, J.A.,Pike, A.C.W. (deposition date: 2007-01-29, release date: 2007-02-20, Last modification date: 2023-12-13)

• Primary citation: Heldring, N.,Pawson, T.,Mcdonnell, D.,Treuter, E.,Gustafsson, J.A.,Pike, A.C.W.; Structural Insights Into Corepressor Recognition by Antagonist-Bound Estrogen Receptors.; J.Biol.Chem., 282:10449-, 2007; PubMed: 17283072; DOI: 10.1074/JBC.M611424200

Experimental method

X-RAY DIFFRACTION (2.1 Å)