1ERE

HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL

Summary for 1ERE

DescriptorESTROGEN RECEPTOR, ESTRADIOL
Functional Keywordsnuclear receptor, transcription factor, steroid, agonist
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Nucleus. Isoform 3: Nucleus P03372
Total number of polymer chains6
Total molecular weight174969.43
Authors
Brzozowski, A.M.,Pike, A.C.W. (deposition date: 1997-09-08, release date: 1998-09-16, modification date: 2009-02-24)
Primary citation
Brzozowski, A.M.,Pike, A.C.,Dauter, Z.,Hubbard, R.E.,Bonn, T.,Engstrom, O.,Ohman, L.,Greene, G.L.,Gustafsson, J.A.,Carlquist, M.
Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature, 389:753-758, 1997
PubMed: 9338790
DOI: 10.1038/39645
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21818011.9%0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1ere
no rotation
Molmil generated image of 1ere
rotated about x axis by 90°
Molmil generated image of 1ere
rotated about y axis by 90°
Copyright © 2013-2016 Protein Data Bank Japan