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1ERE

HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL

Summary for 1ERE

DescriptorESTROGEN RECEPTOR, ESTRADIOL
Functional KeywordsNUCLEAR RECEPTOR, TRANSCRIPTION FACTOR, STEROID, AGONIST,NUCLEAR RECEPTOR
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Nucleus. Isoform 3: Nucleus 
Organ source
Total number of polymer chains6
Total molecular weight174969.43
Authors
Brzozowski, A.M.,Pike, A.C.W. (deposition date: 1997-09-08, release date: 1998-09-16, modification date: 2009-02-24)
Primary citation
Brzozowski, A.M.,Pike, A.C.,Dauter, Z.,Hubbard, R.E.,Bonn, T.,Engstrom, O.,Ohman, L.,Greene, G.L.,Gustafsson, J.A.,Carlquist, M.
Molecular basis of agonism and antagonism in the oestrogen receptor.
Nature, 389:753-758, 1997
PubMed: 9338790
DOI: 10.1038/39645
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24218011.9%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolutionDownload full validation report

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entries available on 2014-10-29
00:00 UTC / 09:00 JST